Effect of Visceral Adipose Tissue on Atherogenic Lipoprotein-lipids in Circulating Plasma Effect of Visceral Adipose Tissue on Atherogenic Lipoprotein-lipids in Circulating Plasma
Physical Activity and Nutrition
v.8
no.3
2004년, pp.303 - 308
Little is known about how visceral adiposity and apolipoprotein CIII in apo B-containing lipoproteinsinfluence plasmatriglyceride (TG) concentrations. The purpose of this study was to determine the relationships ofvisceral adiposity and apo CIII in apo B-containing lipoproteins with plasma TG concentrations in men and women.Procedure: A subgroup of 46 men (n = 20, aged 29.1-33.4 yr) and women (n = 26, aged 29-1 33.8 yr) were recruitedfrom an ongoing population study at our institution. Anthropometric variables including weight, height, and waistcircumference were measured using standard procedures, and body mass index was calculated (kg/m2). Visceral adiposetissue (VAT) was measured with a magnetic resonance imaging. Plasma apolipoproteins, lipids, glucose, and insulinwere measured after an overnight fasting. Results: The men had significantly higher waist circumference, glucose, andTC/HDLC ratio than the women, while the women had significantly higher HDLC and apo AI than the men. Ofparticular, this is the first study to report that VAT and apo CIII in apo B-containing lipoproteins were independentpredictors in determining plasma TG concentrations in Korean adults. Conclusion: Among the obesity indices measuredin the current study, VAT and waist circumference were more consistently associated with the atherogenic lipoproteinlipids(i.e. triacylglycerol, apo CIIIs), fasting insulin and glucose. Consequently, the current study suggest thatinformation on VAT and apo CIII in apo B-containing lipoproteins may provide additional information on thedevelopment of atherogenic lipid profiles and thereby atherosclerosis.
Little is known about how visceral adiposity and apolipoprotein CIII in apo B-containing lipoproteinsinfluence plasma triglyceride (TG) concentrations. The purpose of this study was to determine the relationships ofvisceral adiposity and apo CIII in apo B-containing lipoproteins with plasma TG concentrations in men and women.Procedure: A subgroup of 46 men (n = 20, aged 29.1-33.4 yr) and women (n = 26, aged 29-1 33.8 yr) were recruitedfrom an ongoing population study at our institution. Anthropometric variables including weight, height, and waistcircumference were measured using standard procedures, and body mass index was calculated (kg/m2). Visceral adiposetissue (VAT) was measured with a magnetic resonance imaging. Plasma apolipoproteins, lipids, glucose, and insulinwere measured after an overnight fasting. Results: The men had significantly higher waist circumference, glucose, andTC/HDLC ratio than the women, while the women had significantly higher HDLC and apo AI than the men. Ofparticular, this is the first study to report that VAT and apo CIII in apo B-containing lipoproteins were independentpredictors in determining plasma TG concentrations in Korean adults. Conclusion: Among the obesity indices measuredin the current study, VAT and waist circumference were more consistently associated with the atherogenic lipoproteinlipids(i.e. triacylglycerol, apo CIIIs), fasting insulin and glucose. Consequently, the current study suggest thatinformation on VAT and apo CIII in apo B-containing lipoproteins may provide additional information on thedevelopment of atherogenic lipid profiles and thereby atherosclerosis.
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