Seven flavonoid components were isolated from fr. C of Scutellariae radix which showed antagonistic effects against bradykinin(BK). The results indicated that two oxygen functions (either -OH or $-OCH_3$) at 2'- and 6'-positions and/or an oxygen function at 6-position of flavone seemed to be favored for the BK inhibitory activities. Skullcapflavone-II(IV) which contains $6-OCH_3$, 2'-OH and $6-OCH_3$ in the structure was the most active among the flavones tested.
Woo, In-Taeck ; Park, Kyung-Nam ; Lee, Shin-Ho 2007. "Antimicrobial Activities of Scutellaria baicalensis Georgi Against Various Pathogens and Spoilage Bacteria Isolated from Tofu" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 36(4): 470~475