For comparing with flavones/flavonols, isoflavonoids isolated from Pueraria radix and chemically synthesized from biochanin A were evaluated for the antiinflammatory activity using mouse ear edema test, Isoflavonoids such as daildzein and puerarin hsowed the significant antiinflammatory activity at a dose of 2 mg/mouse, although their activity was generally less than that of flavones/flavonols. 7-O-Substitution of biochanin A was not facorable for the antiinflammatory activity.
2001. "Studies on the Screening of Bioactive Compound Acting on Intracellular Enzymes from Natural Products and Its Mode of Action : Inhibitory Component of Puerariae Radix on Alcohol Dehydrogenase Activity" 약학회지 = Yakhak hoeji, 45(5): 500~505
2005. "" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, 28(10): 1152~1155
Park, Jee-Hee ; Baek, Mok-Ryeon ; Lee, Byung-Hoi ; Yon, Gyu-Hwan ; Ryu, Shi-Yong ; Kim, Young-Sup ; Park, Sang-Un ; Hong, Kyung-Sik 2009. "$\alpha$-Glucosidase and $\alpha$-Amylase Inhibitory Activity of Compounds from Roots Extract of Pueraria thunbergiana" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 17(5): 357~362