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임산부의 영양상태와 모유의 면역물질 함량에 관한 연구

Effect of Maternal Nutritional Status on Immunological Substances in Breast Milk of Korean Women

Abstract

The concentrations of the immunological substances in breast milk and nutritional status were studied in healthy Korean women of middle socioeconomic class. The subjects were recruited at random from obstetric clinics in Seoul. The nutrients intake, prepregnancy BMI, maternal weight gain during pregnancy were studied. The concentrations of lactoferrin(LF), lysozyme(LZ), sIgA, IgG and C3 in colostrum, in transitional milk, and in mature milk, were measured. To elucidate the effect of nutritional status on immunological substances, each components was compared on the basis of either BMI, weight gain, or protein intake. The highest concentrations of the substances were found in colostrum and decreased as lactation progressed. The decline was more prominent in IgG, C3 and sIgA, and less significant in LZ and LF. The colostrum of standard weight gain group showed higher concentrations compared to lower weight gain group. This difference became smaller as the lactation progresses. BMI and nutrient intake status had less significant effect. Lower sIgA was found in lower BMI, in lower weight gain, and lower protein intake groups compared to standard groups, which indicates sIgA is the most affected substance among the measured by nutritional status.

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이 논문을 인용한 문헌 (5)

  1. 1996. "Effect of Dietary Protein Level on Immune Substances in Milk and its Transfer to Pups in Rats" 韓國營養學會誌 = The Korean journal of nutrition., 29(6): 569~577 
  2. 1998. "Anthropometric and Body Compositional Measurements and Pregnancy Outcomes" 韓國營養學會誌 = The Korean journal of nutrition., 31(6): 1057~1065 
  3. 1999. "A Cross-Sectional Study of Nutrient Intakes by Gestational Age and Pregnancy Outcome(I)" 韓國營養學會誌 = The Korean journal of nutrition., 32(8): 877~886 
  4. 2001. "The Effects of Regular Exorcise on Nutrients Intake and Pregnancy Outcome of Pregnant Women in Daegu Area" 韓國營養學會誌 = The Korean journal of nutrition., 34(8): 929~935 
  5. 2003. "Effects of Calcium Supplementations on Mineral Metabolism during Pregnancy with Calcium-Deficient Young Adult Rats" 韓國營養學會誌 = The Korean journal of nutrition., 36(5): 459~469 

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