• 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보

간세포암 환자의 간동맥 화학색전술 후의 예후인자 분석

Analysis of Prognostic Factors in Patients with Hepatocellular Carchinoma after Transcatheter Hepatic Arterial Chemoembolization(TAE)


Purpose : To evaluate long-term survival rates and prognostic factors of patients with hepatocellular carcinoma after TAE. Materials and Methods : 225 patients with hepatocellular carcinoma treated with TAE between January 1988 and December 1994 were studied. Hepatocellular carcinoma was diagnosed either histologically(n=13) orclinically on the basis of findings characteristic for hepatocellular carcinoma obtained using such as diagnostic imaging methods such as ultrasonography, CT, MRI, and angiography as well as on the basis of high serum alpha-fetoprotein level(n=212). TAE was carried out between one and six times(mean, 1.4 time) using a mixture of lipiodol and Adriamycin, together with Gelfoam. Cumulative survival rates from the day of the first TAE were obtained by the Kaplan-Meier method. Parameters likely to influence the prognosis were subjected to univariate analysis using the log-rank test Results : Cumulative survival rates at the end of the first, second, third, fourth, and fifth year were 55.9%, 32.6%, 21.9%, 17.9%, and 15.0%, respectively. The mean survival time was 727 $\pm$ 76 days. Several factors, including Child-Pugh classification, Okuda's stage, tumor size, presence of portalvein invasion by tumor, of arterio-portal shunt, and of extrahepatic metastases, catheter selection level, and number of TAE showed significant correlation with the outcome. Degrees of Lipiodol accumulation in a tumor on follow up CT were also correlated with survival rates. Conclusion : TAE is an effective measure for prolonging thepatient's life expectancy and evaluation of prognostic factor is helpful for prognosis and in deciding on the optimal therapeutic modality.

참고문헌 (25)

  1. Lipiodol CT의 진단적 가치 , 박재형;최병인;조길호(등) , 대한 방사선의학회지 / v.24,pp.179-186, 1988
  2. Hepatocellular carcinoma detected by iodized oil: Use of anticancer agents , Ohishi H;Uchida H;Yoshimura H(et al.) , Radiology / v.154,pp.25-29, 1985
  3. Adriamycin treatment for hepatocellular carcinoma , Elio S;Rosa G;Salvatore L(et al.) , Cancer / v.56,pp.2751-2755, 1985
  4. Transcatheter chemo-embolization effective for treating hepatocellular carcinoma: A histiopathologic study , Sakurai M;Okamura J;Kuroda C , Cancer / v.54,pp.387-392, 1984
  5. 간세포암의 간동맥화학색전요법의 치료효과에 관한 고찰 , 이명숙;안은주;정은철;서정수;이정식 , 대한방사선의학회지 / v.27,pp.447-452, 1991
  6. Transcatheter embolization of hepatocellular carcinoma: Assessment of efficacy in cases of resection following embolization , Nakamura H;Tanka T;Hori S(et al.) , Radiology / v.147,pp.401-405, 1983
  7. Lipiodol retension and massive necrosis after lipiodol-chemoembolization of hepatocellular carcinoma: Correlation between computed tomography and histopathology , Imaeda T;Yamawaki Y;Seki M(et al.) , Cardiovasc Intervent Radiol / v.16,pp.209-213, 1993
  8. Natural history of hepatocellular carcinoma and prognosis in relation to treatment : Study of 850 patients , Okuda K;Ohtsuki T;Obata H(et al.) , Cancer / v.56,pp.918-928, 1985
  9. Transcatheter arterial embolization for hepatocellular carcinoma: Benefits and limitations for unresectable cases with liver cirrhosis evaluated by comparison with other conservative treatments , Sato Y;Fujiwara K;Ogata I(et al.) , Cancer / v.55,pp.2822-2825, 1985
  10. The hepatic artery , Marcovitz J , Surg Gynecol obstet / v.95,pp.644-646, 1952
  11. Effect of repeated transcatheter arterial embolization on the survival time in patients with hepatocellular carcinoma: An analysis by the Cox proportional hazard model , Ideda K;Kumada H;Saitoh S;Arase Y;Chayama K , Cancer / v.68,pp.2150-2154, 1991
  12. Transcatheter aterial embolization of hepatic neoplasms , Nakata K;Khan KN;Nagataki S , Crit Rev Oncol Hematol / v.13,pp.93-105, 1992
  13. Small hepatocellular carcinoma: Treatment with subsegmental transcatheter arterial embolization , Matsui O;Kadoya M;Yashikawa J(et al.) , Radiology / v.188,pp.79-83, 1993
  14. Distribution of iodized oil within the liver after hepatic arterial injection , Miller DL;O'Leary TJ;Girton M , Radiology / v.162,pp.849-852, 1987
  15. Combined peripheral and central chemoembolization of liver tumors: Experience with Lipiodol-Doxorubicin and Gelatin Sponge(L-TAE) , Yoshiyuki S;Peter G;Yoshifumi T(et al.) , Cancer / v.61,pp.238-242, 1988
  16. Use of oily contrast medium for selective drug targeting to tumor: enhanced therapeutic effect and X-ray image , Iwai K;Maeda H;Konno T , Cancer research / v.44,pp.2115-2121, 1984
  17. Hepatocellular carcinom: Treatment with intraarterial iodized oil with and without chemotherapeutic agents , Takayasu K;Shima Y;Muramtsu Y(et al.) , Radiology / v.162,pp.345-351, 1987
  18. 간세포암의 간동맥화학색전요법: 193명의 1년 생존률을 중심으로 , 한준구;박재형;김형석(등) , 대한방사선의학회지 / v.26,pp.624-631, 1990
  19. Treatment of hepatocellular carcinoma with transcatheter arterial embolization , Kenji T;Keisuke N;Yuji K(et al.) , Cancer / v.73,pp.1341-1345, 1994
  20. 근치적 절제술을 시행한 원발성 간세포암에 대한 임상적 연구 , 이홍주;김수태 , 대한외과학회지 / v.38,pp.625-634, 1990
  21. Studies on anticancer treatment with an oily anticancer drug injected into the ligated feeding hepatic artery for liver cancer , Nakakuma K;Tashiro S;Hiraoka T(et al.) , Cancer / v.52,pp.2193-2200, 1983
  22. 간동맥조영술에서의 Lipiodol의 임상적 이용 , 박재형;성규보;신명진;한만청 , 대한방사선의학회지 / v.22,pp.490-494, 1986
  23. Effectiveness of lipiodol in transcatheter arterial embolization of hepatocellular carcinoma , Nakao N;Uchida H;Kamino K , Cancer Chemother Pharmacol / v.31,pp.S72-S76, 1992
  24. Hepatic artery embolization in 120 patients with unresectable hepatoma , Yamada R;Sato M;Kawabata M(et al.) , Radiology / v.148,pp.397-401, 1983
  25. Analysis of prognostotic factors in patients with hepatocellular carcinoma treated by transcatheter arterial embolization , Yamamoto K;Masuzawa M;Kato M(et al.) , Cancer Chemother pharmacol / v.31,pp.S77-S81, 1992

이 논문을 인용한 문헌 (0)

  1. 이 논문을 인용한 문헌 없음


원문 PDF 다운로드

  • 원문 PDF 정보가 존재하지 않습니다.

원문 URL 링크

  • 원문 URL 링크 정보가 존재하지 않습니다.

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일