• 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보


Streptoccus Pneumoniae (pneumococcus), the most common cause of bacterial pneumonia, has an ample polysaccharide (PS) capsule that is highly antigenic and is the source of PS vaccine. This investigation was undertaken to optimize the culture conditions for the production of capsulard PS by type 1 pneumococcus. Among several culture media, brain heart infusion (BHI) and Casitone based media were found to support luxuriant growth of pneumococcus type 1 at the same level. Because BHI medium is rather expensive and more complex than the Casitone based media, the Casitone based media was uwed to study optimization of the culture condition. The phase of growth which accomodated maximum PS production was logarithmic phase. Concentrations of glucose greater than 0.2% did not ehnahce growth or PS production. Substitution of netrogen sources with other resources or supplementation of various concentrations of metal ion (with the exception of calcium ion) had adverse affects on growth and PS production. On the other hand, low level aeration was beneficial for increased PS production. Addition of 3 mg/1 concentration of methionine, phenylalanine, and threonine were found to enhance growth and PS production. The synerigistic effect of all the favorable conditions observed in pneumococcal growth assays provided a two-fold cummulative increase in capsular PS production.

참고문헌 (11)

  1. Oligosaccharides , White, C.A.;J.F. Kennedy;M.F. Chaplin(ed.);J.F. Kennedy(ed.) , Carbohydrate analysis: a practical approach / v.,pp.37-38, 1986
  2. Characterization of some pneumococcal bacteriophage , Porte, R.D.;W.R. Guild , J. Virol. / v.19,pp.659-667, 1976
  3. A new synthetic medium for Diplococcus pneumoniae, and its use for the sutdy of reciprocal transformations at the amiA locus , Sicard, A.M , Genetics / v.50,pp.31-44, 1964
  4. Serotypes of Streptococcus pneumoniae isolated from blood cultures at Boston city hospital between 1979 and 1982 , Barry, M.A.;D.E. Craven;M. Finland , J. Infec. Diseases. / v.149,pp.449-452, 1984
  5. Steptococcus pneumoniae , Willett, H.P.;Joklik, W.K.(ed.);H.P. Willett(ed.);D.B. AmosA(ed.);C.M. Wilfert(ed.) , Zinsser Mcirobiology / v.,pp.368-377, 1988
  6. The pneumococcal polysaccharides: a re-examination , Larm, O.;B. Lindberg , Adv. Carbohydrate Chem. & Biochem. / v.33,pp.295-322, 1976
  7. The pneumococcus and bacterial pneumonia , Storch, G.;M. Schaechter(ed.);G. Medoff(ed.);D. Schlessinger(ed.) , Mechanism of microbial disease / v.,pp.218-227, 1989
  8. Bacterial Polysaccharides , Kenne, L.;B. Lindberg;G.O. Aspinall(ed.) , The Polysaccharides / v.2,pp.287-352, 1983
  9. Quantatitive studies of the spectificity of anti-pneumococcal polysaccharide antibodies, type Ⅲ and Ⅷ , Campbell, J.H.;A.M. Pappenheimer , Immunochem. / v.3,pp.195-212, 1966
  10. Coligan, J.E.;A.M. Krusbeek;D.H. margulies;E.M. Sshevach;W. Strober(eds.) , Current Protocols in Immunology / v.,pp.2.3.1-2.3.4, 1991
  11. A partially defined medium for cultivation of pneumococcus , Adams, M.H.;A.S. Roe , J. Bacteriol. / v.49,pp.401-409, 1945

이 논문을 인용한 문헌 (0)

  1. 이 논문을 인용한 문헌 없음


원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일