Abstract

Residue and recoveries of clindamycin were investigated by reversed-phase high performance liquid chromatography (RP-HPLC) which was infected for the control of streptcoccal infection in Anguilla japonica and Paralichthys olivaceusis. Detection limit was 0.1 ppm. Recoveries of clindamycin in muscles of flounder and eel were 80.4 and 78.8%, respectively. The clindamycin in eel and flounder was detected up to 13 and 15 days after dosing, respectively.

주제어

#Clindamycin   #RP-HPLC   #Residue   #Anguilla Japonica   #Paralichthys Olivaceusis  

저자의 다른 논문

참고문헌 (13)

1. Tissue concentrations of clindamycin after multiple oral doses in normal cats , Brown, S. A.(et al.) , J. Vet. Pharmacol. Ther. / v.13,pp.270-277, 1990
   
2. Diseasea of aquaculture animals and prevenion of drug residues , Heo, G. J.;Shin, K. S.;Lee, M. H. , Kor. J. Food Hyg. / v.7,pp.S7, 1992
   
3. Chemotherapeutic effect of josamycin against natural streptococcal infection in cultured yellowtail , Takemaru, I.;R. Kusuda , Nippon Suisian gakkaish / v.54,pp.1894-1898, 1988
   
4. Development of diseases resistant strains of fish , Wolf, L E , Transactions of the American Fisheries Society / v.83,pp.342-350, 1954
   
5. A comparative study of fish pathogenic streptococcus sp. isolated from saltwater and freshwater and fishes , Kusuda, R.;I. Komasu , Bull. Japan. Soc. Sci. Fish. / v.44,pp.1073-1078, 1978
   
6. Percutaneous absorption of clindamycin in the pig and the rat. , Gray, J. E. , International J. of Dermatology / v.22,pp.314-317, 1983
   
7. An investigation of antibiotic and drug residues in fish , McCracken, A.;S. Fidgeon;J. J. O'Brien;D. Anderson , J. Applied Bacteriol / v.40,pp.61-66, 1976
   
8. Control of bacterial fish disease , Austin, B.;D. A. Austin , Bacterial Fish Pathogens / v.,pp., 1987
   
9. High-performance liquid chromatographic assay of pirlimycin in human serum and urine using 9-fluorenylmethyl-chloroformate , Shah, J. A.;D. J. Weber , J. Chromatogr. / v.309,pp.95-105, 1984
   
10. The in vitro effect of macrolide antibiotics and lincomycin on Streptococcus sp., the etiological agent of streptococcal infection in yellowtall, , Kusuda, R.;S. Onizaki , Seriolar quinqueradiata. Fish Pathol. / v.20,pp.453-457, 1985
    
11. Evaluation of antimicrobial compounds for the control of bacterial kidney disease in rainbow trout, Salmo gairdneri , Austin, B. , J. Fish Dis. / v.8,pp.209-214, 1985
    
12. Distribution an metabolism of antibiotics in the whole animal. clindamycin in the rat , Brodasky, T. F.;C. Lewis;T. E. Eble , Eur. J. Drug Metab. Pharmacok / v.3,pp.149-153, 1977
    
13. In vitro antibacterial activity of josamycin against Streptococcus sp. and various fish pathogenic bacteria , Takemaru, I.;R. Kusuda , Nippon Suisian gakkaish / v.54,pp.1527-1531, 1988
    

이 논문을 인용한 문헌 (0)

1. 이 논문을 인용한 문헌 없음