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흡연자 및 비흡연자의 뇨중 니코틴 및 코티닌 함량

Measurement of Urinary Nicotine and Cotinine Values in Smokers and Non-smokers


This study was conducted to evaluate the personal effects of tobacco smoke and environmental tobacco smoke(ETS) by measuring the concentration of nicotine and cotinine in the urine. While 129 urine samples were being collected, Personal characteristics such as sex, age, number of years since a Person has been a smoker, average consumption number of cigarettes per day, and number of smoker in family were also surveyed. Collected urine samples were used for analysis of nicotine and cotinine by GC/NPD after Passing the extrelut column. In the urine of the smoker, the average contents of nicotine and cotinine were 5.38$\mu\textrm{g}$/ml and 3.14 $\mu\textrm{g}$/ml, respectively. The average contents of nicotine and cotinine were 0.18$\mu\textrm{g}$/ml and 0.07$\mu\textrm{g}$/ml in the urine of male non-smoker, respectively. The contents of nicotine and cotinine in the non-smoker's urine were dependent on sex and age. On the other hand, the contents of nicotine and cotinine in smoker's urine were dependent on average consumption amount of cigarettes per day. Also, there was a direct relation between nicotine levels in the smoker's urine and the average consumption number of cigarettes Per day of smoker. The Possible sources of nicotine and cotinine in the non-smoker's urine seemed to be caused by food, beverage and En, Our results indicate that the number of smoker in family had no effect on increasing nicotine and cotinine contents in the urine of non-smoker.

참고문헌 (20)

  1. Cotinine disposition and effects , Benowitz, N. L.;F. Kuyt;P. Jacob;A. Osman , Clinical Pharmacology and Therapeutics / v.34,pp.604-611, 1983
  2. The human pharmacology of nicotine , Benowitz, N. L. , research advances on alcohol and drug problems / v.9,pp.1-52, 1986
  3. Measurement of current exposure to environmental tobacco smoke , Cummings, K. M.;S. J. Markello;M. Mahoney;A. K. Bhargava;P. D. McElroy;J. R. Marchall , Archives of Envir. Health / v.45,pp.74-79, 1990
  4. The pharmaco kinetics of cotinine in plasma and saliva from non-smoking healthy volunteers , Curvall, M.;C. Elwin;E. Kazemi-Vala;C. Qarholm;C. R. Enzell , European J. of Clinical Pharmacology / v.38,pp.281-287, 1990
  5. Dietary nicotine: A source of urinary cotinine , Davis, R. A.;M. F. Stiles;J. D. Eebethizy;J. H. Reynolds , Fd. Chem. Toxic / v.29,pp.821-827, 1991
  6. Human urine mutagenicity study comparing cigarettes which burn or only heat tobacco , Doolittle, D. J.;C. A. Rahn;G. T. Burger;R. Davis;C. K. Lee;A. W. Hayes , Mutation Research / v.223,pp.221-232, 1989
  7. Nicotine concentrations in urine and saliva of smokers and non-smokers , Feyerabend, C.;T. Higenbottam;M. A. H. Russell , British Medical J. / v.284,pp.1002-1004, 1982
  8. Measuring the exposure of infants to tobacco smoke , Greenberg, R. A.;N. J. Haley;R. A. Etzel;F. A. Loda , The New England J. of Med. / v.310,pp.1075-1078, 1984
  9. Guerin, M. R.;R. A. Jenkins;B. A. Tomkins , The chemistry of environmental tobacco smoke: composition and measurement / v.,pp.137-158, 1992
  10. Home air nicotine levels and urinary cotinine excretion in preschool children , Henderson, F. W.;H. F. Reid;R. Morris;O. L. Wang;S. K. Hammond , Am. Rev. Respir. Dis. / v.140,pp.197-201, 1989
  11. Biochemical markers of smoke absorption and self reported exposure to passive smoking , Jarvos, M. J.;H. Tunstall-Pedoe;C. Feyerabend;C. Vesey;Y. Salloojoo , J. of Epidemiology and Community Health / v.38,pp.335-339, 1984
  12. Comparison of tests used to distinguish smokers from nonsmokers , Javis, M.;H. Tunstall-Pedoe;C. Feyerabend;C. Vesey;Y. Saloojee , American J. of Public Health / v.77,pp.1435-1438, 1987
  13. Application of biochemical intake markers to passive smoking measurement and risk estimation , Jarvis, M. J. , Mutation Research / v.222,pp.101-110, 1989
  14. Assessment of personal exposures to environmental tabacco smoke in british nonsmokers , Phillips, K.;D. A. Howard;D. Browne;J. M. Lewsley , Envir. International / v.20,pp.693-712, 1994
  15. Assessment of air quality in stockholm by personal monitoring of nonsmokers for respirable suspended particles and environmental tobacco smoke , Phillip, K.;M. C. Bentley;D. A. Howard;G. Alvan , J. Work Envir. Health / v.22,pp.1-24, 1996
  16. An interpretation of urinary cotinine values in smokers and non-smokers , Roussel, G.;L. E. Quang;M. L. Migueres;D. Roche;O. G. Ekindjian , Rev. Mal. Resp. / v.8,pp.225-232, 1991
  17. Use of urinary nicotine concentrations to estimate exposure and mortality from passive smoking in non-smokers , Russel, M. A. H.;M. J. Jarvis;R. J. West , British J. of addiction / v.81,pp.275-281, 1986
  18. Simultaneous estimation of nicotine and cotinine levels in biological fluids using high-resolution capillary column gas chromatography combined with solid phase extraction work-up , Teeuwen, H. W. A.;R. J. W. Aalders;J. M. Van Rossum , Molucular Biology Reports / v.13,pp.165-175, 1989
  19. Cotinine in the serum, saliva, and urine of nonsmokers, passive smokers, and active smokers , Wall, M. A.;J. Johnson;P. Jacob;N. L. Benowitz , American J. of Public Health / v.78,pp.699-701, 1988
  20. Verification of smoking history in patients after infarction using urinary nicotine and cotinine measurements , Wilcox, R. G.;J. Hughes;J. Roland , British Med. J. / v.2,pp.1026-1028, 1979

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