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Korean journal of biological sciences, v.2 no.3, 1998년, pp.371 - 375
Park, Jeong-Soo (Laboratory of Immunology,Research Institute for Medical Sciences) , Kim, Young-Tai (Department of Microbiology, Ajou University Medical School) , Lee, Chan-Hee (Department of Intermal Medicine, Yonsei University Medical School) , Youn, Jung-Koo (Department of Microbiology, Ajou University Medical School) , Jang, Young-Ju (Laboratory of Immunology,Research Institute for Medical Sciences)
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Twenty-one monoclonal anti-DNA autoantilndies were produced by fusing spleen cells from an autoimmune MRL/lpr mouse with SP2/0 myeloma cells. Hybridomas generated by the fusions were chosen for cloning on the basis of DNA binding by supernatant antibody. Each monoclonal antibody was purified to homo...
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