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논문 상세정보

사염화탄소에 의해 유발된 간독성에 대한 상백피 추출물의 간보호효과

Protective Effects of Extracts of Mori Cortex Radicis on Carbon Tetrachloride-induced Hepatotoxicity

약학회지 = Yakhak hoeji v.43 no.3 , 1999년, pp.391 - 396  
Abstract

In order to evaluate the protective effects of extracts of Mori cortex radicis on carbon tetrachloride-induced hepatotoxicity, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, lactic dehydrogenase, malondiadehyde values and glutathione S-transferase activity were measured in ICR mice. The activities of serum aminotransferase and the hepatic content of lipid peroxide after carbon tetrachloride-treatment were markedly increased than normal control but those levels were significantly decreased by the treatment of butanol fraction of Mori cortex radicis mathanol extract. Glutathione S-transferase activity was decreased by carbon tetrachloride than control, but that also inhibited by the treatment of butanol fraction of Mori cortex radicis methanol extract. These results demonstrate a possible hepatoprotective role of extract role of extract of Mori cortex radicis against ${CCl_4}-induced$ hepatoxicity in vivo.

참고문헌 (17)

  1. 한국 생약학 교수협의회 , 본초학 / v.,pp.614, 1994
  2. a new flavone derivatives from the root barks of the cultivated mulberry tree (Morus alba L.) , Nomura,T.;Fukai,T. , Chem. Pharm. Bull. / v.28,pp.2548, 1980
  3. Carbon tetrachloride hepatotoxicity , Recknigel,R.O. , Pharmacol. Rev. / v.19,pp.145, 1967
  4. Glutathione S-transferases , Habig,W.H.;Pabst,M.J.;Jakoby,W.B. , J. Biol. Chem. / v.249,pp.7130, 1974
  5. Assay method for antihepatotoxic activity using carbon tetrachloride induced cytotoxicity in primary cultured hepatocytes , Kiso,Y.;Tohkin,M.;Hikino,H. , Planta med. / v.49,pp.222, 1983
  6. Structure-activity relationships of polymethoxy-flavones and other flavonoids as inhibitors of non-enzymic lipid peroxidation , Mora,A.;Paya,M.;Rios,J.L.;Alcaraz,M.J. , Biochem. Pharm. / v.40,pp.793, 1990
  7. Lipid peroxidation , Logani,M.K.;Davis,R.E. , Lipids / v.15,pp.485, 1979
  8. Protein measurement with the folin phenol reagent , Lowry,O.H.;Rosebrough,N.J.;Farr,A.L.:Randall,R.J. , J. Biol. Chem. / v.193,pp.265, 1951
  9. 生藥의 機能과 美白效果 , 池田孝夫;提龍彦 , フレグランスジヤ-ナル / v.6,pp.59, 1990
  10. Isolation and hypoglycemic activity of moran A, a glycoprotein of Morus alba root barks , Hikino,H.;Mizuno,T.;Oshima,Y.;Konno,C. , Plant med. / v.51,pp.159, 1985
  11. A colorimetric method for the determination of serum glutamc oxaloacetic and glutamic pyrivic transaminase , Reitman,S.;Frankel,S. , Am. J. Clinic. Pathol. / v.28,pp.56, 1957
  12. Constituents of the cultivated mulberry tree. XXV. Structures of two natural hypotensive Diels-Alder type adducts, mulberrofurans F and G from the cultivated mulberry tree (Morus Lhou Koidz) , Fukai,T.;Hanno,Y.;Hirakura,K.;Nomura,T.;Uzawa,J. , Chem. Phar. Bull. / v.33,pp.3195, 1985
  13. Berry,M.N.;Edward,A.M.;Barritt,G.J.;Burdon(ed.) , Laboratory technique in biochemistry and molecular biology / v.,pp.15, 1991
  14. 한대석(외) , 생약학 / v.,pp.118, 1991
  15. The regulation as hepatic glutathione , Naei,K.;Tak,Y.A.;Murad,O. , Ann. Rev. Pharmacol. Toxicol. / v.25,pp.715, 1985
  16. The crucial role of oxygen partial pressures in haloalkane free radical mediated lipid peroxidation , Groot,H.;Noll.T. , Bichem. Pharmacol. / v.35,pp.15, 1986
  17. Effect of 3-methylchloroanthrene induction on the CCl₄-induced changes in rat hepatic microsomal enzyme system , Maynard,E.H.;Bitterns,S.;James,R.G. , Bichem. Pharmacol. / v.21,pp.745, 1971

이 논문을 인용한 문헌 (3)

  1. 2003. "Effects of Mori Folium and Crataegus pinnatifida Leave Extracts on $CC1_4$-induced Hepatotoxicity in Rats" 약학회지 = Yakhak hoeji, 47(4): 206~211 
  2. 2007. "" Journal of toxicology and public health : an official journal of the Korean Society of Toxicology, 23(1): 11~17 
  3. 2007. "" 大韓獸醫學會誌 = Korean journal of veterinary research, 47(3): 325~331 

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