$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
안녕하세요!
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보

사철쑥 (Artemisia Capillaris Thunberg)이 흰쥐 혈액 및 간지질 대사에 미치는 영향

Effects of Artemisia Capillaris Thunberg on the Plasma and Liver Lipid Metabolism in Rats

초록

사철쑥 (Artemisia capitlaris Thunberg)으로 성인병의 예방목적으로 흰쥐 (Sprague-Dawley rats)의 혈액 및 간지질 대사에 미치는 영향에 대한 효과를 알아보았다. 1) 사료이용효율은 L, LM, LP군에서 높았다 (p < 0.01). 혈청의 콜레스테롤 농도, 동 맥 경화지수 (p <0.01), 중성지질 (p < 0.01)은 L, LM, LP군에서 높았지만, 사철쑥 분말 첨가에 의해 HDL-콜레스테롤과 HTR를 증가시켰다 (p < 0.01). 2) 혈청 및 간 조직의 과산화지질은 C군에 비하여 L군이 유의적으로 많았으며, 사철쑥 첨가시 감소하였다 (p < 0.05). 3) 간 조직의 지방침착은 L군에서 지방양성구의 크기와 분포가 두드러지게 높았고. LM군, LP길군에서는 감소하였다. 이상의 결과는 사철쑥은 혈액 및 간의 지질조성 및 지질 대사에 바람직한 효과를 갖는 것으로 보인다. 이는 사철쑥이 성인병예방에 유용한 기능성 식품으로서 가치가 있을 것으로 사료된다.

Abstract

This study was performed to investigate the influence of dietary and extract foods from A. capilliaris Thunberg on plasma and liver lipid metabolism in male Sprague-Dawley rats. For the experiment of liver and plasma lipid metabolism, Rats were find diets containing normal concentrations of fat or high concentrations of lard and two different preparations of A. capillaris Thunberg ; control diet (group C),50 mg/kg body weight A. capillary Thunberg methanol extract (group M), 6 g/kg diet A. capillary Thunberg dried powder (group P), high lard control diet (group L), 50 mg/kg body weight A. capillaris Thunberg with high lard (group LM) and 6 g/kg diet A. capillary Thunberg with hi\ulcorner lard (group LP). Effects of A. capillary Thunberg on plasma total cholesterol. High-density lipoprotein (HDL) cholesterol, Atherogenic index, triglyceride, plasma and liver peroxide contents, fatty acid composition of liver lipid and the distribution of fat droplets of liver. Supplementation of A. capillaris Thunberg resulted in lower plasma cholesterol, atherogenic index and triglyceride, and higher HDL-cholesterol in rats find high lard diets. However, these effects were not observed with low level of fat (groups C, M and P). A shift caused by feeding high lard diets in increased plasma and liver peroxides, saturated fatty arid composition of liver lipid and the more frequent distribution of fat droplets in liver could be reversed by feeding A. capillary Thunberg. This study suggests that A. capillary Thunberg co alter lipid metabolism in plasma and liver.

저자의 다른 논문

참고문헌 (49)

  1. Evaluation of artemisia inculta for anti-inflammatory activity in rats , Tariq MM;Mossa JS;Al-Yahya MA;Parmar NS;Ageel AM , Am. J. Chin Med / v.15,pp.127-132, 1987
  2. Effects of scoparone on liver function , Cho MK;Choe SY;Hong SM;Kim BS , J. Korean Soc. Food Sci. Nutr. / v.27,pp.344-349, 1988
  3. AIN-76 diet should we change the formulation , Reeves PG , J. Nutr. / v.119,pp.1081, 1983
  4. A study on the nutritional effects in rats by feeding basal diet supplemented with mugwort powder , Haw IW;Lee SD;Hwang WI , J. Korean Soc. Food Nutr. / v.14,pp.123-130, 1985
  5. Yoo HG , Allelopathic effects of essential oils of some plant species in artemisia on selected plants and microbes / v.,pp.1-141, 2000
  6. Effects of artemisia iwayomogi extracts on antioxidant enzymes in rats administered benzo(α)pyrene , Nam SM;Kim JG;Ham SS;Kim SJ;Chung ME;Chung CK , J. Korean Soc. Food Sci. Nutr / v.28,pp.199-204, 1999
  7. Characterization of polysaccharides from artemisia capillaris and artemisia sylvatica , Hwang EJ;Kwon HC;Jung CM;Moon HI;Kim SY;Zee OP;Lee KR , Yakhak Hoeji / v.43,pp.423-428, 1999
  8. Effect of acanthopanacis cortex boiling extract solutions on fat accumulation in the obese rats induced by high fat dietary , Sung TS;Son GM;Bae MJ;Choi C , J. Korean Soc. Food Sci. Nutr. / v.21,pp.9, 1992
  9. Studies on the activities of tannins and related compounds from medicinal plants and drugs. Ⅶ Effects of extracts of leaves of artemisia species and caffeic acid and chlorogenic acid on lipid metabolic injury in rats fed peroxidized oil , Kimura Y;Okuda H;Okuda T;Hatano T;Agata I;Arichi S , Chem Pharm Butl / v.33,pp.2028-2034, 1985
  10. The chemical composition of persimmon (Diospyros Kaki, Thumb) leaf tea , Joung SY;Lee SJ;Sung NJ;Jo JS;Kang SK , J. Korean Soc. Food Nut. / v.24,pp.720-726, 1995
  11. Effects of mugwort dried orange peel and duchung on lipid metabolism in hyperlipidemia rats , Kim JH;Wang SG , Korean J. Nutrition / v.30,pp.895-903, 1997
  12. Effects of feeding basal diet supplemented with mugwort powder on the serum components in rat , Lee SD;Park HH , Korean J. Food & Nutr / v.13,pp.446-452, 2000
  13. Antimicrobial activity of extracts and coumaric acid isolated from artemisia princeps var. orientalis , Park SK;Park JC , Korean J. Biotechnol Bioeng / v.9,pp.506-511, 1994
  14. Kim TJ , Korean resources plants Ⅳ / v.,pp.260-267, 1996
  15. Effects of artemisia capillaris kitamura ethanol extract on lowering serum and liver lipids in rats , Nam S.M.;Ham S.S.;Oh D.H.;Kang I.J.;Lee S.Y.;Chung C.K. , J. Korean Soc. Food Sci. Nutr. / v.27,pp.338-343, 1998
  16. Effect of artemisia iwayomogi water extract on hepatic injury by carbon tetrachloride in rats I. Effect on serum AST, ALT, LDH activities, lipid conte nt and liver peroxide content , Kim KS;Park JH , Korean J. Vet. Res. / v.32,pp.347-356, 1992
  17. Stamler J. , Introduction to risk factors in coronart artery disease in medical communication / v.,pp.1-3, 1981
  18. A study on the nutritional effects in rats by feeding basal diet supplemented with mugwort powder , Haw IW;Lee SD;Hwang WI , J. Korean Soc. Food Nutr / v.14,pp.123-130, 1985
  19. Microbal digestion of complex carbohydrates in man , Cummings J.H. , Proc. Nutr Soc. / v.43,pp.35, 1984
  20. Effects of green tea infusion on the preneoplastic lesions and peroxidation in rat hepatocarcinogenesis , Kim HS;Kim HS;Choi H. , Korean J. Community Nutr / v.2,pp.633, 1997
  21. A simple method for isolation and purification of total lipids from animal tissues , Folch J;Lees M;Sloand-stanley GH , J. Biol Chem / v.226,pp.497-500, 1957
  22. Studies on the nutritional components of mugwort artemisia mongolica fisher , Sim YJ;Han YS;Chun HJ , Korean J. Food Sci. Technol / v.24,pp.49-53, 1992
  23. Lee H.J. , Effects of artemisia capillaris on liver lipid metabolism in rats and apoptosis in HeLa cells / v.,pp., 2001
  24. Denzac Sheehan;Barbara B. Hrapchak , Theory and practice of histotechnology / v.,pp., 1980
  25. The effect of scoparone on the hepatic bromobenzene metabolizing enzyme system in rats , Kim EJ;Lee CK;Choi JW , Kor. J. Pharmacogn / v.23,pp.81-88, 1992
  26. National Research Council(NRC) , / v.,pp.687, 1979
  27. Biochemical evaluation of artemisia capillaris flos , Yamahara J;Matsuda H;Sawada T;Mibu H;Fujimura H , Yakagaku Zasshi / v.102,pp.285, 1982
  28. Effect of dietary polyunsaturated/saturated fatty acid ratio and dietary vitamin E on lipid peroxidation in the rat , Buckingham KW , J. Nutr / v.115,pp.1425-1435, 1985
  29. Effects of alginic acid cellulose and pectin level on bowel function in rats , Lee HJ;Hwang EH , Korean J. Nutrition / v.30,pp.465-477, 1997
  30. Effects of artemisia selengensis methanol extract on ethanol-induced hepatotoxicity in rat liver , Kim KS;Lee MY , J. Korean Soc. Food Sci. Nutr. / v.25,pp.581-587, 1996
  31. Effect of ginseng on fat accumulation in the obese rats induced by high fat diet , Kim SI;Kim YS;Jeon BS;Lim C , Korean J. Ginseng Sci. / v.10,pp., 1986
  32. Induction of apoptosis with an extract of artemisia asiatica attenuates the severity of cerulein-induced pancreatitis in rats , Hahm KB;Kim JH;You BM;Kim YS;Cho SW;Yim H;Ahn BO;KIm WB , Panereas / v.17,pp.153-157, 1998
  33. Kim SM , Amino acid analysis and effect of artemisia sp. in rat blood / v.,pp.1-46, 1986
  34. Bioactive constituents and utilities of artemisia sp. as medicinal herb and foodstuff , Lee SD;Park HH;Kim DW;Bang HB , Korean J. Food & Nutr. / v.13,pp.490-505, 2000
  35. Effect of artemisia princeps var orientalis and circium japonicum var ussuriense on serum lipid of hyperlipidemic rat , Lim S.S.;Lee J.H. , Korean J. Nutr / v.30,pp.12-18, 1997
  36. Rim S.N. , Studies on the Biological activities artemisia / v.,pp.1-46, 1995
  37. Preparation fatty acid ethyl esters and dimethylacetals from lipids with boron fluoride-methanol , Morrison WR;Smith LM , J. Lipid Res / v.5,pp.600-608, 1964
  38. The rold of alternative medicine for the treatment of cancer , Kim N.D.;Lim Y.H. , Journal of Korean Association of Cancer Prevention / v.3,pp.40-45, 1998
  39. Ministry of Health and Welfare Republic of Korea , Yearbook of health and welfare statistics / v.4,pp., 1999
  40. Dietary fats and cancer , Kenneth KC , Am J. Clin Nutr. / v.53,pp.1064-1067, 1991
  41. Hypoglycemic activity of artemisia herba alba , Twaij HA;Al-Badr AA , J. Ethnopharmacol / v.43,pp.167-171, 1994
  42. Yagi K. , Lipid peroxidation in biology and medicine / v.,pp.223, 1982
  43. Park JM , Studies of scoparone on the detoxication mechanism in mice, Ph D Thesis / v.,pp., 1988
  44. Dietary fiber , Kritchevsky D. , Ann Rev Nutr / v.8,pp.301, 1988
  45. Ahn JM , Studies on the herb that make practical application of foods / v.,pp.1-56, 1988
  46. Oil seeds refining & oil consumption pattern , Kim SH , The Korean Nutrition Society / v.,pp.546-552, 1997
  47. Biological activity of the soluble extracts from artemisia princeps var orientalis acted on cardiovascula system , Rim SS;Lee JH , Korean J. Nutr / v.30,pp.634-638, 1997
  48. Hypotensive activity of some dihydroxycoumarins and their congeners , Thakur RS;Bagadia SC;Sharma ML , Experientia / v.34,pp.158, 1978
  49. Iwata I. , Jouranl of Medical Technology / v.20,pp.941-943, 1976

이 논문을 인용한 문헌 (1)

  1. Lee, Hyoung-Ja ; Kim, Kee-Hwan ; Park, Jong-Kun ; Hwang, Eun-Hee 2008. "Effects of Artemisia Capillaris Thunberg on Apoptosis in HeLa Cells" 韓國營養學會誌 = The Korean journal of nutrition., 41(1): 22~30 

DOI 인용 스타일