$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
안녕하세요!
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보

사염화탄소 유발 간독성에 대한 금은화의 작용

Effect of Lonicera Japonica Flower on CCl4-induced Hepatotoxicity

Abstract

Methanol extract of Lonicera Japonica (Caprifoiaceae) flower significantly inhibited serum GPT, GOT, LDH and AIP activities at the doses of 500 and 1,000mg/kg in $CCl_4$-intoxicated rats. As confirmed with the fiactions of hexane, chlorofom, ethyl acetate, butanol and water, the butanol fraction showed significant inhibition of increased activity of serum GPT, LDH and AIP in $CCl_4$-intoxicated rats, indicating that the most active components might be contained in the butanol fraction.

참고문헌 (25)

  1. Bensky, D. and Gamble, A. (1986). Chinese Herbal Medicine, Materia Medica, pp. 85-86 Eastland Press, Incorporated 
  2. Chang, C. W., Lin, M. T., Lee, S. S., Liu, K. C., Hsu, F. L. and Lin J. Y. (1995). DifFerential inhibition of reverse trans-criptase and cellular DNA polymerase-activities by lignans isolated from chinese herbs, AntiviraI Res., 27, 367-374 
  3. Chang, H. W., Baek, S. H., Chung, K. W., Son, K. H., Kim, H. P. and Kang S. S. (1994). Inactivation of phospholipase A2 by naturally occurring biflavoniod, ochnaflavone, Biochem. Biophys. Res. Commun., 205, 843-849 
  4. Chung, K. C., Kwon, D. Y, Baek, S. H., Kim, S. H. and Chang, H. W. (1988). Effect of Lonicerae Flos' ethyl acetate Fraction on Mutagenicity, Yakhak Hoeji, 32, 328-333 
  5. Han, W. Y. (1990). Study on anti-inflammatory effect of Lonicera japonica., Department of Phannacy Graduate School, Sookmyung Women's University, MS Thesis 
  6. Hofmann, A. F. and Popper, H. (1987). Ursodeoxycholic acid for primaiy biliary cirrhosis, Lancet, 2, 398-399 
  7. Kawai, H., Kuroyanagi, M., Umehara, K., Ueno, A. and Satake, M. (1998). Studies on the saponins of Lonicera japonica Thumb. Chem. Pharm. BuIL, 36, 4769-4775 
  8. Kawano, S., Nakagawa, H., Toga, H. (1982). Investigations on physiological values of blood in industrial workers, Report 3. Serum colloid reaction and enzyme activity values, Sangyo. Igaku, 24, 275-283 
  9. King, J. (1972). Effect of hydrogen ion concentration on lactate dehydrogenase (LDH) assays, Clin, Chem., 18, 1443 
  10. Mehrotra, R., Singh, C., Popli, S. P. (1998). Isolation of secoxyloganin from Lonicera japonica and conversion into secologanin,J. Nat. Prod., 51, 319-321 
  11. Park, J. 0, (1997). Studies on the flavonoid components of Lonicera japonica and their biological activities. Depart- ment of Pharmacy Graduate School, Yeungnam University, Ph. D. Thesis 
  12. Park J. 0. (1989). Study on the inhibition of lipid peroxidation by Lonicerae Flos' EtOAc fraction., Department of Pharmacy Graduate School, Ycungnam University, MS Thesis 
  13. Plaa, G. L. and Hewitt, W. R. (1982). Principles and Methods of Toxicology, pp. 407-445, Raben Press 
  14. Rao, V. C and Nehendale, H. M. (1991). Colchicine antimiosis abolishes $CCl_4$ autoprotection, Toxicol Pathol., 19, 597--606 
  15. Reitman, S. and Frankel, S (1957). A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases, Am. J. Clin, Pathol., 28, 56-63 
  16. Samuel, Y. L. and Yonsop, C. (1986). Laboratory Methods in Clinical Pathology, pp. 229-230, Yonsei University Press, Seoul 
  17. Sherlock, D. S. (1992). Disease of Liver and Biliary System. 8th ed. Oxford, Blackwell Scientific publications 
  18. Sim, K. S., Moon, C. K., Ryu, C. K., Cheon, I. S., Chung, J. H. and Park, D. S. (1979. Giinnol, sterols and glycosides from Lonicerae Flos, Yakhak NonmunjiP, 4, 79, Seoul Univ. Press, Seoul 
  19. Son K. H., Jung K. Y., Chang H. W., Kim H. P. and Kang. S. S. (1994). Triterpenoid saponins from the aerial parts of Lonicera japonica. Phytochemistry, 35, 1005-1008 
  20. Taguchi, H., Iketani, Y., Niitsu, K. and Mori, K (1985). Pharmaceuticals for tre.atment of influenza virus infection, pp. 60, 243, 016, Jpn. Kokai Tokkyo Koho J., Tokyo 
  21. Tang, W., Eisenbrand, G. (1992). Chinese Drugs of Plant Origin, pp. 621-625 Springer-Verlag, Berlin 
  22. Wang, G., Zbu, X., Wang, J., Jia, W., Yuan, Y., Nan, P. and Yuan, P. (1992). Analysis of Chemical constituent of essential oil in Lonicera japonica Thumb. cultivated on the northern plain of Henan Province, Chung Kuo Chung Yao Tsa Chih, 17, 268-270 
  23. Wang, L., Yee, L. (1981). Studies on the components of the flowers of Lonicera japonica Thumb, and their antibacterial activities, Hsiang-kang Ch'in Huk Hsue Than Hsueh Pao, 8, 1115 
  24. 上海科技出版社編(1985). 中藥大辭典, pp. 523-526, 小學館, 東京 
  25. 陳再民(1982). 原設韓方醫藥大辭典(中國藥學大典), pp.I601, 講談社, 中國 

이 논문을 인용한 문헌 (5)

  1. 2004. "Anti-lipid Peroxidation Activity of Acanthopanax var, albeofructus" 약학회지 = Yakhak hoeji, 48(1): 99~103 
  2. Yoo, Hyo-Jeong ; Park, Mee-Yeon ; Choi, Hae-Yun ; Kim, Jong-Dae 2010. "Mouse Single Oral Dose Toxicity Test of Lonicerae Flos Aqueous Extracts" 대한한방내과학회지 = The journal of internal Korean medicine, 31(3): 539~553 
  3. Kim, Yong ; Yang, Su-Young ; Oh, Young-Seon ; Lee, Jin-Woo ; Lee, Yong-Koo ; Park, Yang-Chun 2010. "Research trends of Lonicera japonica over the last 10 years" 論文集 : 大田大學校 韓醫學硏究所. 韓醫學編, 19(1): 17~23 
  4. Ku, Sae-Kwang ; Lee, Young-Joon 2010. "Effects of Lonicerae Flos on the 6-n-propyl-2-thiouracil (PTU)-induced Rat Hypothyroidism" 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine, 24(4): 630~637 
  5. Kim, Byoung-Woo 2011. "Effects of Hwangryeun Extract on the Recovery of Liver Function in $CCl_4$-exposed Rats" 동의생리병리학회지 = Journal of physiology & pathology in Korean Medicine, 25(6): 1020~1025 

원문보기

원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일