$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Diabetes, Glucose Transport and Hypoglycaemic Agents 원문보기

The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology, v.12 no.4, 2004년, pp.202 - 208  

Khil, Lee-Yong (Faculty of Medicine, University of Calgary)

Abstract AI-Helper 아이콘AI-Helper

Diabetes mellitus is a complex metabolic derangement with hyperglycaemia being the most characteristic symptom of diabetes. Hyperglycaemia can be caused by an increase in the rate of glucose production by the liver or by a decrease in the rate of glucose use by peripheral tissues. Impaired glucose t...

주제어

참고문헌 (70)

  1. Ahmed, Z., Smith, B.J. and Pillay, T.S. (2000). The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor. FEBS Lett. 475, 31-34 

  2. Ahn, M.Y., Katsanakis, K.D., Bheda, F. and Pillay, T.S. (2004). Primary and essential role of the adaptor protein APS for recruitment of both c-Cbl and its associated protein CAP in insulin signaling. J. BioI. Chem. 279,21526-21532 

  3. Alessi, D.R, James, S.R, Downes, C.P., Holmes, A.B., Gaffney, P.R, Reese, C.B. and Cohen, P. (1997). Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Curro BioI. 7,261-269 

  4. Arribas, M., Valverde, A.M., Burks, D., Klein, J., Farese, R.Y., White, M.F and Benito, M. (2003). Essential role of protein kinase C zeta in the impairment of insulin-induced glucose transport in IRS-2-deficient brown adipocytes. FEBS Lett. 536, 161-166 

  5. Attele, A.S., Zhou, Y.P., Xie, J.T., Wu, J.A, Zhang, L., Dey, L., Pugh, W., Rue, P.A, Polonsky, K.S. and Yuan, C.S. (2002). Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. Diabetes. 51, 1851-1858 

  6. Bailey, C.J. and Turner, R.C. (1996). Metformin. N. Engl. J. Med. 334, 574-579 

  7. Baldwin, S.A (1993). Mammalian passive glucose transporters: members of an ubiquitous family of active and passive transport proteins. Biochim. Biophys. Acta. 1154, 17-49 

  8. Baumann, C.A, Ribon, V., Kanzaki, M., Thurmond, D.C., Mora, S., Shigematsu, S., Bickel, P.E., Pessin, J.E. and Saltiel, A.R. (2000). CAP defines a second signalling pathway required for insulinstimulated glucose transport. Nature. 407,202-207 

  9. Carvalho, E, Schellhorn, S.E., Zabolotny, J.M., Martin, S., Tozzo, E., Peroni, O.D., Houseknecht, K.L., Mundt, A., James, D.E. and Kahn, B.B. (2004). GLUT4 overexpression or deficiency in adipocytes of transgenic mice alters the composition of GLUT4 vesicles and the subcellular localization of GLUT4 and insulinresponsive aminopeptidase. J. BioI. Chem. 279, 21598-21605 

  10. Chiang, S.H., Baumann, C.A., Kanzaki, M., Thurmond, D.C., Watson, R.T., Neudauer, C.L., Macara, I.G., Pessin, J.E. and Saltiel, A.R (2001). Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TCIO. Nature. 410, 944-948 

  11. Choi, S.B., Wha, J.D. and Park, S. (2004). The insulin sensitizing effect of homoisoflavone-enriched fraction in Liriope platyphylla Wang et Tang via PI3-kinase pathway. Life Sci. 75, 2653-2664 

  12. Choi, S.B., Wha, J.D. and Park, S. (2004). The insulin sensitizing effect of homoisoflavone-enriched fraction in Liriope platyphylla Wang et Tang via PI3-kinase pathway. Life Sci. 75, 2653-2664 

  13. Ciaraldi, T.P., Huber-Knudsen, K., Hickman, M. and Olefsky, J.M. (1995). Regulation of glucose transport in cultured muscle cells by novel hypoglycemic agents. Metabolism. 44, 976-981 

  14. Ciaraldi, T.P., Kong, A.P., Chu, N.Y., Kim, D.D., Baxi, S., Loviscach, M., Plodkowski, R., Reitz, R., Caulfield, M., Mudaliar, S. and Henry, R.R. (2002). Regulation of glucose transport and insulin signaling by troglitazone or metformin in adipose tissue of type 2 diabetic subjects. Diabetes. 51, 30-36 

  15. Czech, M.P. and Corvera, S. (1999). Signaling mechanisms that regulate glucose transport. J. Bioi. Chem. 274, 1865-1868 

  16. DeFronzo, R.A. (1988). The triumvirate: $\beta$ -cell, muscle, liver: a collusion responsible for NIDDM. Diabetes. 37,667-687 

  17. DeFronzo, R.A., Gunnarsson, R., Bjorkman, O., Olsson, M. and Wahren, J. (1985). Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J. Clin. Invest. 76, 149-155 

  18. Ducluzeau, P.H., Fletcher, L.M., Vidal, H., Laville, M. and Tavare, J.M. (2002). Molecular mechanisms of insulin-stimulated glucose uptake in adipocytes. Diabetes Metab. 28, 85-92 

  19. Fajans, S.S and Conn, J.W. (1965). Prediabetes, subclinical diabetes, and latent clinical diabetes: interpretation, diagnosis and treatment. In: On the Nature and Treatment of Diabetes (D.S. Leibel and G.S. Wrenshall, Eds.), pp. 641-656. Excerpta Medica, Amsterdam 

  20. Farese, R.V., Ishizuka, T., Standaert, M.L. and Cooper, D.R. (1991). Sulfonylureas activate glucose transport and protein kinase C in rat adipocytes. Metabolism. 40, 196-200 

  21. Ginsberg, H., Kimmerling, G., Olefsky, J.M. and Reaven, G.M. (1975). Demonstration of insulin resistance in untreated adult onset diabetic subjects with fasting hyperglycemia. J. Clin. Invest. 55, 454-461 

  22. Guyton, A.C. and Hall, J.E. (1996). Textbook of medical physiology. Elsevier Science 

  23. Hill, M.M., Clark, S.F., Tucker, D.F., Birnbaum, M.J., James, D.E. and Macaulay, S.L. (1999). A role for protein kinase Bbeta/Akt2 in insulin-stinmlated GLUT4 translocation in adipocytes. Mol. Cell Biol. 19,7771-7781 

  24. Hundal, R.S., Krssak, M., Dufour, S., Laurent, D., Lebon, Y., Chandramouli, V., Inzucchi, S.E., Schumann, W.C., Petersen, KF., Landau, B.R and Shulman, G.I. (2000). Mechanism by which metformin reduces glucose production in type 2 diabetes. Diabetes. 49, 2063-2069 

  25. Inzucchi, S.E. (2002). Oral antihyperglycemic therapy for type 2 diabetes: scientific review. JAMA 287, 360-372 

  26. James, D.E. and Piper, R.C. (1994). Insulin resistance, diabetes, and the insulin-regulated trafficking of GLUT-4. J. Cell Biol. 126, 1123-1126 

  27. Jiang, T., Sweeney, G., Rudolf, M.T., Klip, A., Traynor-Kaplan, A and Tsien, R.Y. (1998). Membrane-permeant esters of phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273, 11017-11024 

  28. Jun, H., Bae, H.Y., Lee, B.R., Koh, K.S., Kim, Y.S., Lee, K.W., Kim, H. and Yoon, J. (1999). Pathogenesis of non-insulindependent (type II) diabetes mellitus (NIDDM) - genetic predisposition and metabolic abnormalities. Adv. Drug Deliv. Rev. 35,157-177 

  29. Kahn, B.B. (1992). Facilitative glucose transporters: regulatory mechanisms and dysregulations in diabetes. J. Clin. Invest. 89, 1367-1374 

  30. Khil, L.Y., Cheon, A.J., Chang, T.S. and Moon, C.K (1997). Effects of calcium on brazilin-induced glucose transport in isolated rat epididymal adipocytes. Biochem. Phannacol. 54, 97-101 

  31. Khil, L.Y, Han, S.S., Kim, S.G., Chang, T.S., Jeon, S.D., So, D.S. and Moon, C.K (1999). Effects of brazilin on GLUT4 recruitment in isolated rat epididymal adipocytes. Biochem. Phannacol. 58, 1705-1712 

  32. Kotani, K., Carozzi, A.J., Sakaue, H., Hara, K, Robinson, L.J., Clark, S.F., Yonezawa, K, James, D.E. and Kasuga, M. (1995). Requirement for phosphoinositide 3-kinase in insulin-stimulated GLUT4 translocation in 3T3-Ll adipocytes. Biochem. Biophys. Res. Commun. 209, 343-348 

  33. Kruszynska, Y.T. and Olefsky, J.M. (1996). Cellular and molecular mechanisms of non-insulin dependent diabetes mellitus. J. Investig. Med. 44,413-428 

  34. Lane, M.D., Flores-Riveros, J.R., Hresko, Re., Kaestner, K.H., Liao, K, Janicot, M., Hoffman, R.D., McLenithan, J.C., Kastelic, T. and Christy, R.J. (1990). Insulin-receptor tyrosine kinase and glucose transport. Diabetes Care. 13, 565-575 

  35. Liu, M.-L., Gibbs, E.M., McCoid, S.C., Milici, A.J., Stukenbrok, H.A., McPherson, R.K., Treadway, J.L. and Pessin, J.E. (1993). Transgenic mice expressing the human GLUT4/muscle-fat facilitative glucose transporter protein exhibit efficient glycemic control. Proc. Natl. Acad. Sci. USA. 90, 11346-11350 

  36. Maier, V.H., Melvin, D.R., Lister, C.A., Chapman, H., Gould, G.W. and Murphy, G.J. (2000). v- and t-SNARE protein expression in models of insulin resistance: normalization of glycemia by rosiglitazone treatment corrects overexpression of cellubrevin, vesicle- associated membrane protein-2, and syntaxin 4 in skeletal muscle of Zucker diabetic fatty rats. Diabetes. 49, 618-625 

  37. Martin, S., Rarnm, G., Lyttle, C.T., Meerloo, T., Stoorvogel, W. and James, D.E. (2000). Biogenesis of insulin-responsive GLUT4 vesicles is independent of brefeldin A-sensitive trafficking. Traffic. I, 652-660 

  38. Mastick, C.C., Brady, M.J. and Saltiel, A.R. (1995). Insulin stimulates the tyrosine phosphorylation of caveolin. J. Cell Biol. 129,1523-1531 

  39. Meyer, C., Dostou, J.M., Welle, S.L. and Gerich, J.E. (2002). Role of human liver, kidney, and skeletal muscle in postprandial glucose homeostasis. Am. J. Physiol. Endocrinol. Metab. 282, E419-427 

  40. Millar, C.A, Shewan, A, Hickson, G.R., James, D.E. and Gould, G.W. (1999). Differential regulation of secretory compartments containing the insulin-responsive glucose transporter 4 in 3T3Ll adipocytes. Mol. Biol. Cell. 10, 3675-3688 

  41. Moller, D.E. (2001). New drug targets for type 2 diabetes and the metabolic syndrome. Nature. 414:821-827 

  42. Moore, M.C., Cherrington, A.D. and Wasserman, D.H. (2003). Regulation of hepatic· and peripheral glucose disposal. Best Pract. Res. Clin. Endocrinol. Metab. 17, 343-364 

  43. MUdaliar, S. and Henry, R.R. (2001). New oral therapies for type 2 diabetes mellitus: the glitazones or insulin sensitizers. Annu. Rev. Med. 52, 239-257 

  44. Pagliassotti, M.J. and Horton, T.J. (1994). Hormonal and neural regulation of hepatic glucose uptake. In The Role of the Liver in Maintaining Glucose Homeostasis (M.J. Pagliassotti, S. Davis and A.D. Cherrington Eds.), pp. 45-70. R.G. Landis, Austin, TX 

  45. Pirart, J. (1978). Diabetes mellitus and its degenerative complications: a prospective study of 4400 patients observed between 1947 and 1973. Diabetes Care. 1, 168-188 

  46. Randhawa, V.K., Bilan, P.J., Khayat, Z.A., Daneman, N., Liu, Z., Rarnlal, T., Volchuk, A., Peng, X..R., Coppola, T., Regazzi, R.,Trimble, W.S. and Klip, A (2000). VAMP2, but not VAMP3/cellubrevin, mediates insulin-dependent incorporation of GLUT4 into the plasma membrane of L6 myoblasts. Mol. Biol. Cell. 11, 2403-2417 

  47. Rea, S. and James, D.E. (1997). Moving GLUT4: the biogenesis and trafficking of GLUT4 storage vesicles. Diabetes. 46, 1667-1677 

  48. Rea, S., Martin, L.B., McIntosh, S., Macaulay, S.L., Ramsdale, T., Baldini, G. and James, D.E. (1998). Syndet, an adipocyte target SNARE involved in the insulin-induced translocation of GLUT4 to the cell surface. J. Biol. Chem. 273, 18784-18792 

  49. Reaven, G.M. (1983). Insulin resistance in noninsulin-dependent diabetes mellitus. Does it exist and can it be measured? Am. J. Med. 74, 3-17 

  50. Ribon, V. and Saltiel, A R (1997). Insulin stimulates tyrosine phosphorylation of the proto-oncogene product of c-Cbl in 3T3-Ll adipocytes. Biochem. J. 324, 839-845 

  51. Ribon, V., Printen, J.A., Hoffman, N.G., Kay, B.K. and Saltiel, A.R. (1998). A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-Ll adipocytes. Mol. Cell Biol. 18, 872-879 

  52. Rifkin, H. and Porte, D. (1997). Diabetes Mellitus, Theory and Practice. Elsevier Science 

  53. Sarges, R, Hank, R.F., Blake, J.F., Bordner, J., Bussolotti, D.L., Hargrove, D.M., Treadway, J.L. and Gibbs, E.M. (1996). Glucose transport-enhancing and hypoglycemic activity of 2-methyl-2-phenoxy-3-phenylpropanoic acids. J. Med. Chem. 39, 4783-4803 

  54. Shepherd, P.R., Withers, D.J. and Siddle, K. (1998). Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. Biochem. J. 333,471-490 

  55. Shintani, M., Nishimura, H., Yonemitsu, S., Ogawa, Y, Hayashi, T., Hosoda, K., Inoue, G. and Nakao, K. (2001). Troglitazone not only increases GLUT4 but also induces its translocation in rat adipocytes. Diabetes. 50, 2296-2300 

  56. Simpson, F, Whitehead, J.P. and James, D.E. (2001). GLUT4--at the cross roads between membrane trafficking and signal transduction. Traffic. 2, 2-11 

  57. Standaert, M,L., Bandyopadhyay, G., Kanoh, Y., Sajan, M.P. and Farese, R.V. (2001). Insulin and PIP3 activate PKC-zeta by mechanisms that are both dependent and independent of phosphorylation of activation loop (T41O) and autophosphorylation (T560) sites. Biochemistry. 40, 249-255 

  58. Strowski, M.Z., Li, Z., Szalkowski, D., Shen, X., Guan, X.M., Juttner, S., Moller, D.E. and Zhang, B.B. (2004). Small-molecule insulin mimetic reduces hyperglycemia and obesity in a nongenetic mouse model of type 2 diabetes. Endocrinology. 145, 5259-5268 

  59. Tanner, L.I. and Lienhard, G.E. (1987). Insulin elicits a redistribution of transferrin receptors in 3T3-L1 adipocytes through an increase in the rate constant for receptor externalization. J. Biol. Chem. .262, 8975-8980 

  60. Tozzo, E., Shepherd, P.R., Gnudi, L. and Kahn, B.B. (1993). Increased basal and insulin-stimulated glucose transport and metabolism in isolated adipocytes from transgenic mice overexpressing GLUT4 selectively in fat. Diabetes. 42 (Suppl. 1), 13A 

  61. Tsuneki, H., Ishizuka, M., Terasawa, M., Wu, J.B., Sasaoka, T. and Kimura, I. (2004). Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans. BMC Pharmacol. 4, 18 

  62. UK Prospective Diabetes Study (UKPDS) Group. (1998). Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 352, 837-853 

  63. Wallberg-Henriksson, H. and Zierath, J.R. (2001). GLUT4: a key player regulating glucose homeostasis? Insights from transgenic and knockout mice (review). Mol. Membr. Biol. 18,205-211 

  64. Watson, R.T., Shigematsu, S., Chiang, S.H., Mora, S., Kanzaki, M., Macara, I.G., Saltiel, A.R and Pessin, J.E. (2001). Lipid raft microdomain compartmentalization of TCIO is required for insulin signaling and GLUT4 translocation. Cell. BioI. 154, 829-840 

  65. World Heath Organization Study Group (1985). Diabetes mellitus. WHO Tech. Rep. Ser. 727, 1-113 

  66. Wu, L.Y, Juan, C.C., Hwang, L.S., Hsu, Y.P., Ho, P.H. and Ho, L.T. (2004). Green tea supplementation ameliorates insulin resistance and increases glucose transporter IN content in a fructose-fed rat model. Eur. J. Nutr. 43, 116-124 

  67. Yoon, J.W. and Jun, H.S. (1998). Insulin-dependent diabetes mellitus. In Encyclopedia ofImmunology (M.M. Roitt and PJ. Delves, Eds.), pp. 1390-1398. Academic Press, London 

  68. Yoon, J.W. and Jun, H.S. (2001). Cellular and molecular pathogenic mechanisms of insulin-dependent diabetes. Ann. N. Y. Acad. Sci. 928, 200-211 

  69. Zhang, B., Salituro, G., Szalkowski, D., Li, Z., Zhang, Y, Royo, I., Vilella, D., Diez, M.T., Pelaez, F., Ruby, C., Kendall, R.L., Mao, X., Griffm, P., Calaycay, J., Zierath, J.R, Heck, J.V., Smith, R.G. and Moller, D.E. (1999). Discovery of a small molecule insulin mimetic with antidiabetic activity in mice. Science. 284,974-977 

  70. Zimmerman, B.R. (1997). Sulfonylureas. Endocrinol. Metab. Clin. NorthAm. 26, 511-521 

관련 콘텐츠

이 논문과 함께 이용한 콘텐츠

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로