$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
안녕하세요!
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보

Porcine circovirus 2 국내 분리주의 유전적 특성

Genetic characterization of porcine circovirus 2 Korean isolates

Abstract

In order to obtain the genetic informations of the Korean isolates of porcine circovirus 2 (PCV2), nucleotide sequences of total genome of three isolates and open reading frame 2 (ORF2) of four isolates were determined and compared with those of other reference PCV2 isolates. Nucleotide sequences of 3 isolates showed over 99% homology with those of reference strain (GenBank accession no. AF027217). Point mutations were mainly determined on ORF2 regions but little on ORF1 regions. The patterns of pointmutated sites and nucleotide substitution on ORF2 regions were generally consistent between Korean isolates, and these mutated sites observed in Korean isolates were also relatively similar to those of foreign isolates. Phylogenetic analysis of nucleotide or amino acid sequences showed that there were minor branches consisting of three clusters; cluster of Korea, Canada and America, cluster of Spain and Taiwan, and the last cluster of French and China isolates. These results suggested that Korean PCV2s were probably originated from North America such as Canada or USA. The genetic informations obtained from this study could be useful for the research of diagnosis and pathogenecity of PCV2.

참고문헌 (33)

  1. Allan, G., Meehan, B., Todd, D., Kennedy, S., McNeilly, F., Ellis, J., Clark, E. G., Harding, J., Espuna, E., Botner, A. and Charreyre, C. Novel porcine circoviruses from pigs with wasting disease syndromes. Vet. Rec. 1998, 142, 467-468 
  2. Allan, G. M., McNeilly, F., Kennedy, S., Daft, B., Clark, E. G., Ellis, J. A., Haines, D. M., Meehan, B. M. and Adair, B. M. Isolation of porcine circoviruslike viruses from pigs with a wasting disease in the USA and Europe. J. Vet. Diagn. Invest. 1998, 10, 3-10 
  3. Boevink, P., Chu. P. W. and Keese, P. Sequence of subterranean clover stunt virus DNA: affinities with the geminiviruses. Virology. 1995, 207, 354-361 
  4. Harding, R. M., Burns, T. M. and Dale, J. L. Viruslike particles associated with banana bunchy top disease contain small single-stranded DNA. J. Gen. Virol. 1991, 72, 225-230 
  5. Lukert, P., de Boer, G. F. and Dale, J. L. The Circoviridae. In: Murphy, F.A., Fauquet, C.M., Bishop, D.H.L., eds. Virus Toxonomy. 6th Rep. Int. Committee Taxon. Viruses. pp. 166-168, Vienna: Springer-Verlag, 1995 
  6. Lyoo, K. S., Park, Y. H. and Park, B. K. Prevalence of porcine reproductive and respiratory syndrome virus, porcine circovirus type 2 and porcine parvovirus from aborted fetuses and pigs with respiratory problems in Korea. J. Vet. Sci. 2001, 2, 201-207 
  7. Tischer, I., Mields, W., Wolff, D., Vagt, M. and Griem, W. Studies on epidemiology and pathogenicity of porcine circovirus. Arch. Virol. 1986, 91, 271-276 
  8. Meehan, B. M., McNeilly, F., Todd, D., Kennedy, S., Jewhurst, V. A., Ellis, J. A., Hassard, L. E., Clark, E. G., Haines, D. M. and Allan, G. M. Characterization of novel circovirus DNAs associated with wasting syndromes in pigs. J. Gen. Virol. 1998, 79, 2171-2179 
  9. 박최규, 김현수. 이유자돈 전신소모성증후군 이환 자돈에서의 바이러스성 원인체 검색 및 porcine circovirus 2 분리동정. 대한수의학회지. 2004, 44, 561-569 
  10. Mankertz, A., Persson, F., Mankertz, J., Blaess, G. and Buhk, H. J. Mapping and characterization of the origin of DNA replication of porcine circovirus. J. Virol. 1997, 71, 2562-2566 
  11. Meehan, B. M., Creelan, J. L., McNulty, M. S. and Todd, D. Sequence of porcine circovirus DNA: affinities with plant circoviruses. J. Gen. Virol. 1997, 78, 221-227 
  12. Hamel, A. L., Lin, L. L. and Nayar, G. P. Nucleotide sequence of porcine circovirus associated with postweaning multi-systemic wasting syndrome in pigs. J. Virol. 1998, 72, 5262-5267 
  13. Mahe, D., Blanchard, P., Truong, C., Arnauld, C., Le Cann, P., Cariolet, R., Madec, F., Albina, E. and Jestin, A. Differential recognition of ORF2 protein from type 1 and type 2 porcine circoviruses and identification of immunorelevant epitopes. J. Gen. Virol. 2000, 81, 1815-1824 
  14. Choi, C. and Chae, C. In-situ hybridization for the detection of porcine circovirus in pigs with postweaning multisystemic wasting syndrome. J. Comp. Pathol. 1999, 121, 265-270 
  15. Lyoo, Y. S., Kim, J. H. and Park, C. K. Identification of porcine circoviruses with genetic variation from lymph nodes collected in pigs with PMWS. Kor. J. Vet. Sci. 1999, 39, 353-358 
  16. Morozov, I., Sirinarumitr, T., Sorden, S. D., Halbur, P. G., Morgan, M. K., Yoon, K. J. and Paul, P. S. Detection of a novel strain of porcine circovirus in pigs with postweaning multisystemic wasting syndrome. J. Clin. Microbiol. 1998, 36, 2535-2541 
  17. Miyata, H., Tsunoda, H., Kazi, A., Yamada, A., Khan, M. A., Murakami, J., Kamahora, T., Shiraki, K. and Hino, S. Identification of a novel GC-rich 113-nucleotide region to complete the circular, singlestranded DNA genome of TT virus, the first human circovirus. J. Virol. 1999, 73, 3582-3586 
  18. Ellis, J., Hassard, L., Clark, W., Harding, J., Allan, G., Willson, P., Strokappe, J., Martin, K., McNeilly, F., Meehan, B., Todd, D. and Haines, D. Isolation of circovirus from lesions of pigs with postweaning multisystemic wasting syndrome. Can. Vet. J. 1998, 39, 41-51 
  19. Ritchie, B. W., Niagro, F. D., Latimer, K. S., Lukert, P. D., Steffens, W. L. 3rd, Rakich, P. M. and Pritchard, N. Ultrastructural, protein composition, and antigenic comparison of psittacine beak and feather disease virus purified from four genera of psittacine birds. J. Wildl. Dis. 1990, 26, 196-203 
  20. Tischer, I., Geldblom, H., Vettermann, W. and Koch, M. A. A very small porcine virus with circular singlestranded DNA. Nature. 1982, 295, 64-66 
  21. Chang, S. F., Sgro, J. Y. and Parrish, C. R. Multiple amino acids in the capsid structure of canine parvovirus coordinately determine the canine host range and specific antigenic and hemagglutination properties. J. Virol. 1992, 66, 6858-6867 
  22. Allan, G. M. and Ellis, J. A. Porcine circoviruses: a review. J. Vet. Diagn. Invest. 2000, 12, 3-14 
  23. Nawagitgul, P., Morozov, I., Bolin, S. R., Harms, P. A., Sorden, S. D. and Paul, P. S. Open reading frame 2 of porcine circovirus type 2 encodes a major capsid protein. J. Gen. Virol. 2000, 81, 2281-2287 
  24. Todd, D., Niagro, F. D., Ritchie, B. W., Curran, W., Allan, G. M., Lukert, P. D., Latimer, K. S., Steffens, W. L. and NcNulty, M. S. Comparison of three animal viruses with circular single-stranded DNA genomes. Arch. Virol. 1991, 117, 129-135 
  25. Sambrook, J. F., Russell, D. W. and Irwin, N. Molecular Cloning: A laboratory manual. 3rd ed, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 2000 
  26. Fenaux, M., Halbur, P. G., Gill, M., Toth, T. E. and Meng, X. J. Genetic characterization of type 2 porcine circovirus (PCV-2) from pigs with postweaning multisystemic wasting syndrome in different geographic regions of North America and development of a differential PCR-restriction fragment length polymorphism assay to detect and differentiate between infections with PCV-1 and PCV-2. J. Clin. Microbiol. 2000, 38, 2494-2503 
  27. Meehan, B. M., McNeilly, F., McNair, I., Walker, I., Ellis, J. A., Krakowka, S. and Allan, G. M. Isolation and characterization of porcine circovirus 2 from cases of sow abortion and porcine dermatitis and nephropathy syndrome. Arch. Virol. 2001, 146, 835-842 
  28. Rohde, W., Randles, J. W., Langridge, P. and Hanold, D. Nucleotide sequence of a circular singlestranded DNA associated with coconut foliar decay virus. Virology. 1990, 176, 648-651 
  29. Allan, G. M., McNeilly, F., Cassidy, J. P., Reilly, G. A., Adair, B., Ellis, W. A. and McNulty, M. S. Pathogenesis of porcine circovirus; experimental infections of colostrum deprived piglets and examination of pig foetal material. Vet. Microbiol. 1995, 44, 49-64 
  30. Bassami, M. R., Berryman, D., Wilcox, G. E. and Raidal, S. R. Psittacine beak and feather disease virus nucleotide sequence analysis and its relationship to porcine circovirus, plant circoviruses, and chicken anaemia virus. Virology. 1998, 249, 453-459 
  31. Mankertz, A., Domingo, M., Folch, J. M., LeCann, P., Jestin, A., Segales, J., Chmielewicz, B., Plana-Duran, J. and Soike, D. Characterisation of PCV-2 isolates from Spain, Germany and France. Virus Res. 2000, 66, 65-77 
  32. Nishizawa, T., Okamoto, H., Konoshi, K., Yoshizawa, H., Miyazawa, Y. and Mayumi, M. A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology. Biochem. Biophys. Res. Commun. 1997, 241, 92-97 
  33. Mankertz, A., Mankertz, J., Wolf, K. and Buhk, H. J. Identification of a protein essential for replication of porcine circovirus. J. Gen. Virol. 1998, 79, 381-384 

이 논문을 인용한 문헌 (4)

  1. Kim, Eun-Gyeong ; Hwang, Bo-Won ; Lee, Jong-Min ; Son, Byeong-Guk ; Park, Ho-Jung ; Kim, Tho-Kyoung 2009. "Rapid detection and quantification of porcine circovirus type 2 (PCV 2) DNA in Real-time PCR" 韓國家畜衛生學會誌 = Korean journal of veterinary service, 32(4): 299~306 
  2. Jin, Wen ; Han, Jeong-Hee 2009. "Genetic characterization and phylogenetic analysis of porcine circovirus type 2 field strains isolated from Korean pocine circovirus disease (PCVD) pigs" 韓國家畜衛生學會誌 = Korean journal of veterinary service, 32(1): 1~10 
  3. Chu, Keum-Suk 2011. "Application of a nested-polymerase chain reaction assay to differentiate the genotypes of porcine circovirus 2" 韓國家畜衛生學會誌 = Korean journal of veterinary service, 34(1): 13~18 
  4. Kim, Min-Hee ; Park, Jong-Sik ; Lee, Min-Kweon ; Kim, Chul-Ho ; Shin, Jung-Sup ; Kim, Hyun-Joon 2011. "Characterization of the infection pattern of porcine respiratory disease complex (PRDC) in the northern area of Gyeongsangnam-do, Korea" 韓國家畜衛生學會誌 = Korean journal of veterinary service, 34(2): 133~138 

원문보기

원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일