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Determination of Flavonoids, Tannins and Ellagic Acid in Leaves from Rubus L. Species

Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.27 no.11, 2004년, pp.1114 - 1119  

Gudej, Jan (Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Bialystok, ul., Department of Pharmacognosy, Faculty of Pharmacy, Medical University of dz, ul.) ,  Tomczyk, Michal (Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Bialystok, ul.)

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This paper describes the quantitative determination of flavonoids, tannins and ellagic acid in the leaves from wild and cultivated variations of Rubus L. species (Rosaceae): raspberry (2 wild and 13 cultivars) and blackberry (3 wild and 3 cultivars). The content of flavonoids was analyzed using spec...

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  • Samples were analyzed on the Waters HPLC system (Milford, MA, USA) equipped with Waters 600E pump, a 600 Controller and a 996 PDA detector scanning between 190 and 400 nm. The data were collected and analyzed with the Millenium32 Chromatography Manager V4.

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  • The content of flavonoids according to the Christ-Müllers method was calculated as quercetin and as hyperoside. Flavonoid content, based on the Christ-Mullers method was higher for the blackberry leaves than for the raspberry leaves and varied between 0.
  • et al, 2001). The tannins content was established by using DAB 10 (1998) and 기lagic acid by the HPLC method after acid hydrolysis. These polyphenolics are widely distributed in the plant kingdom and it is claimed that they have beneficial effects on health as antioxidant, antimicrobial, anti-inflammatory, antiviral and as anticarcinogen agents (Havsteen, 2002; Thiem and Gooelinska, 2004; Priyadarsini et al.
  • Total flavonoid content was measured according to the Christ-Müller's method (Christ and MuI아; 1960; Polish Pharmacopoeia, 2002) using a SPECORD 40 Spectrophotometer (Analytik Jena, Germany). Content of flavonoids in all sources was calculated as quercetin and hyperoside and samples for the analysis were prepared according to the Polish Pharmacopoeia VI.
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참고문헌 (36)

  1. Alice, L. A. and Campbell, Ch. S., Phylogeny of Rubus (Rosaceae) based on nuclear ribosomal DNA internal transcribed spacer region sequences. Am. J. Bot., 86, 81-97 (1999) 

  2. Amakura, Y., Okada, M., Tsuji, S., and Tonogai, Y., High-performance liquid chromatographic determination with photodiode array detection of ellagic acid in fresh and processed fruits. J. Chromatogr. A, 896, 87-93 (2000) 

  3. Barch, D. H., Rundhaugen, L. M., Stoner, G. D., Pillay, N. S., and Rosche, W. A., Structure-function relationships of the dietary anticarcinogen ellagic acid. Carcinogenesis, 17, 265-269 (1996) 

  4. Borkowski, B., Lutomski, J., Skrzydlewska, E., and Zygmunt, B., Rosliny lecznicze w fitoterapii, IRiPZ, Poznan pp. 470-471(1994) 

  5. Burn, J. H. and Withell, E. R., A principle in raspberry leaves which relaxes uterine muscle. Lancet, 5, 1-3 (1941) 

  6. Christ, B. and Muller, K. H., Determination of the amount of flavonol derivatives in drugs. Arch. Pharm., 293, 1033-1042 (1960) 

  7. Czygan, F. Ch., Die Himbeere-Rubus idaeus L. Portrait einer Arzneipflanze. Z. Phytother., 16, 366-374 (1995) 

  8. DAB 10 Deutsches Arzeneibuch, Amtliche Ausgabe, Deutcher Apotheker Verlag, Stuttgart p. 197 (1998) 

  9. Gudej, J., Kaempferol and quercetin glycosides from Rubus idaeus L. leaves. Acta Polon. Pharm., 60, 313-316 (2003) 

  10. Gudej, J. and Rychlinska, I., Flavonoid compounds from the leaves of Rubus idaeus L. Herba Pol., 42, 257-261 (1996) 

  11. Gudej, J., Tomczyk, M., Urban, E., and Tomczykowa, M., Analysis of chemical composition of Rubus saxatilis L. leaves. Herba Pol., 44, 340-344 (1998) 

  12. Gwozdecki, J., Zeszyty pomologiczne, and Malina i Jezyna. Instytutu Sadownictwa i Kwiaciarstwa, Skierniewice pp. 5-53 (1996) 

  13. Hakkinen, S., Heinonen, M., Karenlampi, S., Mykkanen, H., Ruuskanen, J., and Torronen, R., Screening of selected flavonoids and phenolic acids in 19 berries. Food Res. Int., 32, 345-353 (1999) 

  14. Hakkinen, S. H., Karenlarnpi, S. O., Mykkanen, H. M., Heinonen, I. M., and Torronen, A. R., Ellagic acid content in berries: influence of domestic processing and storage. Eur. Food Res. Technol., 212, 75-80 (2000) 

  15. Havsteen, B., The biochemistry and medical significance of flavonoids. Pharmacol. Therap., 96, 67-202 (2002) 

  16. Heslop-Harrison, Y., Rubus L. In: Tutin TG et al. (eds.) Flora Europaea. Vol. II, Cambridge University Press p. 7-25 (1968) 

  17. Krawczyk, A., Thiem, B., and Szkudlarek, M., High-performance liquid chromatography of ellagic acid from the leaves of Rubus chamaemorus L. Chem. Anal. (Warsaw), 48, 891-899 (2003) 

  18. Krzaczek, T., Phenolic acids in some tannin drugs of the Rosaceae family. Farm. Pol., 40, 475-477 (1984) 

  19. Marczal, G., Qualitative studies of the tannin content of Rubus idaeus leaf. Herb. Hung., 2, 347-357 (1963) 

  20. Mullen, W., McGinn, J., Lean, M. E. J., MacLean, M. R., Gardner, P., Duthie, G. G., Yokota, T., and Crozier, A., Ellagitannins, flavonoids, and other phenolics in red raspberries and their contribution to antioxidant capacity and vasorelaxation properties. J. Agric. Food Chem., 50, 5191-5196 (2002) 

  21. Okuda, T., Yoshida, T., Hatano, T., Iwasaki, M., Kubo, M., Orime, T., Yoshizaki, M., and Naruhashi, N., Hydrolysable tannins as chemotaxonomic markers in the Rosaceae. Phytochemistry, 31, 3091-3096 (1992) 

  22. Olszewska, M., Glowacki, R., Wolbioe, M., and Bald, E., Quantitative determination of flavonoids in the flowers and leaves of Prunus spinosa L. Acta Polan. Pharm., 58, 199-203 (2001) 

  23. Ozarowski, A., and Jaroniewski, W., Rooeliny lecznicze i ich praktyczne zastosowanie, IWZZ, Warszawa pp. 184, 243 (1989) 

  24. Patel, A. V., Rojas-Vera, J., and Dacke, C. G., Therapeutic constituents and actions of Rubus species. Curr. Med. Chem., 11, 1501-1512 (2004) 

  25. Polish Pharmacopoeia VI, Polish Pharmaceutical Society(eds.), Warszawa p. 150 (2002) 

  26. Priyadarsini, K. I., Khopde, S. M., Kumar, S. S., and Mohan, H., Free radical studies of ellagic acid, a natural phenolic antioxidant. J. Agric. Food Chem., 50, 2200-2206 (2002) 

  27. Robbers, J. E., and Tyler, V. E., In: Tyler's Herbs of choice: the therapeutic use of phytomedicinals, The Haworth Herbal Press, New York-London pp. 63-64, 194-195 (1999) 

  28. Rojas-Vera, J., Patel, A. V., and Dacke, C. G., Relaxant activity of raspberry (Rubus idaeus) leaf extract in guinea-pig ileum in vitro. Phytother. Res., 16, 665-668 (2002) 

  29. Rommel, A. and Wrolstad, R. E., Ellagic acid content of red raspberry juice as influenced by cultivar, processing and environmental factors. J. Agric. Food Chem., 41, 1951-1960 (1993) 

  30. Shepherd, T., Robertson, G. W., Griffiths, D. W., and Birch, A. N. E., Epicuticular wax ester and triacylglycerol composition in relation to aphid infestation and resistance in red raspberry (Rubus idaeus L.). Phytochemistry, 50, 1255-1267 (1999) 

  31. Simpson, M., Parsons, M., Greenwood, J., and Wade, K., Raspberry leaf in pregnancy: its safety and efficacy in labor. J. Midwifery Womens Health, 46, 51-59 (2001) 

  32. Sticher, O., Quality of Ginkgo preparations. Planta Med., 59, 2-11(1993) 

  33. Thiem, B. and Gooslinska, O., Antimicrobial activity of Rubus chamaemorus leaves. Fitoterapia, 75, 93-95 (2004) 

  34. Tomczyk, M. and Gudej, J., Quantitative analysis of flavonoids in the flowers and leaves of Ficaria verna Huds. Z. Naturforsch., 58c, 762-764 (2003) 

  35. Wojcik, E., Phytochemical investigation of Rubus plicatus blackberry. Acta Polon. Pharm., 46, 386-390 (1989) 

  36. Daniel, E. M., Krupnick, A. S., Heur, Y. H., Blinzler, J. A., Nims, R. W., and Stoner, G. D., Extraction, stability and quantitation of ellagic acid in various fruits and nuts. J. Food Comp. Anal., 2, 338-349 (1989) 

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