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Placental Superoxide Dismutase, Genetic Polymorphism, and Neonatal Birth Weight

Journal of preventive medicine and public health = 예방의학회지, v.37 no.4, 2004년, pp.306 - 311  

Hong, Yun-Chul (Department of Preventive Medicine, Seoul National University College of Medicine and Medical Research Center) ,  Lee, Kwan-Hee (Department of Occupational and Environmental Medicine, Inha University College of Medicine) ,  Im, Moon-Hwan (Department of Obstetrics and Gynecology, Inha University College of Medicine) ,  Kim, Young-Ju (Department of Obstetrics and Gynecology, Ewha Women's University College of Medicine) ,  Ha, Eun-Hee (Department of Preventive Medicine, Ewha Women's University College of Medicine)

Abstract AI-Helper 아이콘AI-Helper

Background : The roles of antioxidants in the placenta and genetic susceptibility to oxidant chemicals in relation to neonatal birth weight have not been elucidated. We determined whether the level of placental manganese superoxide dismutase (MnSOD) and its genetic polymorphism plays any role in oxi...

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  • In this report, we hypothesize that the placenlal level of MnSOD is associated with lipid peroxidation and birth weight. Because the placenta has been reported to be an important source of maternal lipid peroxide levels, maternal urinary MDA level may represent the oxidant-antioxidaiit balance of the placenla [18].
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참고문헌 (30)

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