• 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보


The antibacterial actions of two amino acid oxidases, a D-amino acid oxidase from hog kidney and a L-amino acid oxidase from the venom of Agkistrodon halys, were investigated, demonstrating that both enzymes were able to inhibit the growth of both Gram-positive and Gram-negative bacteria, and that hydrogen peroxide, a product of their enzymatic reactions, was the antibacterial factor. However, hydrogen peroxide generated in the enzymatic reactions was not sufficient to explain the degree to which bacterial growth was inhibited. A fluorescence labeling assay showed that both of these two enzymes could bind to the surfaces of bacteria. To the best of our knowledge, this is the first report regarding the antibacterial activity of the D-amino acid oxidases.

참고문헌 (14)

  1. D'Aniello, A., A. Vetere, and L. Petrucelli. 1993. Further study on the specificity of D-amino acid oxidase and D-aspartate oxidase and time course for complete oxidation of D-amino acids. Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 105, 731-734 
  2. Marcotte, P. and C. Walsh. 1976. Vinylglycine and proparglyglycine: complementary suicide substrates for L-amino acid oxidase and D-amino acid oxidase. Biochemistry 15, 3070-3076 
  3. Stiles, B.G., F.W. Sexton, and S.A. Weinstein. 1991. Antibacterial effects of different snake venoms: purification and characterization of antibacterial proteins from Pseudechis australis (Australian king brown or mulga snake) venom. Toxicon 29, 1129-1141 
  4. Sakurai, Y., H. Takatsuka, A. Yoshioka, T. Matsui, M. Suzuki, K. Titani, and Y. Fujimura. 2001. Inhibition of human platelet aggregation by L-amino acid oxidase purified from Naja naja kaouthia venom. Toxicon 39, 1827-1833 
  5. Li, Z.Y., T.F. Yu, and E.C. Lian. 1994. Purification and characterization of L-amino acid oxidase from king cobra (Ophiophagus hannah) venom and its effects on human platelet aggregation. Toxicon 32, 1349-1358 
  6. Ali, S.A., S. Stoeva, A. Abbasi, J.M. Alam, R. Kayed, M. Faigle, B. Neumeister, and W. Voelter. 2000. Isolation, structural, and functional characterization of an apoptosis-inducing L-amino acid oxidase from leaf-nosed viper (Eristocophis macmahoni) snake venom. Arch. Biochem. Biophys. 384, 216-226 
  7. Suhr, S.M. and D.S. Kim. 1996. Identification of the snake venom substance that induces apoptosis. Biochem. Biophys. Res. Commun. 224, 134-139 
  8. Torii, S., K. Yamane, T. Mashima, N. Haga, K. Yamamoto, J.W. Fox, M. Naito, and T. Tsuruo. 2000. Molecular cloning and functional analysis of apoxin I, a snake venom-derived apoptosis- inducing factor with L-amino acid oxidase activity. Biochemistry 39, 3197-3205 
  9. Geyer, A., T.B. Fitzpatrick, P.D. Pawelek, K. Kitzing, A. Vrielink, S. Ghisla, and P. Macheroux. 2001. Structure and characterization of the glycan moiety of L-amino-acid oxidase from the Malayan pit viper Calloselasma rhodostoma. Eur. J. Biochem. 268, 4044-4053 
  10. Zhang, H., M. Teng, L. Niu, Y. Wang, Y. Wang, Q. Liu, Q. Huang, Q. Hao, Y. Dong, and P. Liu. 2004. Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino acid oxidase with cell apoptosisinducing activity from Agkistrodon halys pallas venom. Acta Cryst. D60, 974-977 
  11. Ehara, T., S. Kitajima, N. Kanzawa, T. Tamiya, and T. Tsuchiya. 2002. Antimicrobial action of achacin is mediated by L-amino acid oxidase activity. FEBS Lett. 531, 509-512 
  12. Souza, D.H., L.M. Eugenio, J.E. Fletcher, M.S. Jiang, R.C. Garratt, G. Oliva, and H.S. Selistre-de-Araujo. 1999. Isolation and structural characterization of a cytotoxic L-amino acid oxidase from Agkistrodon contortrix laticinctus snake venom: preliminary crystallographic data. Arch. Biochem. Biophys. 368, 285- 290 
  13. Tempone, A.G., H.F. Jr. Andrade, P.J. Spencer, C.O. Lourenco, J.R. Rogero, and N. Nascimento. 2001. Bothrops moojeni venom kills Leishmania spp. with hydrogen peroxide generated by its L-amino acid oxidase. Biochem. Biophys. Res. Commun. 280, 620-624 
  14. Skarnes, R.C. 1970. L-amino-acid oxidase, a bactericidal system. Nature 225, 1072-1073 

이 논문을 인용한 문헌 (0)

  1. 이 논문을 인용한 문헌 없음


원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일