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Purification and Characterization of Recombinant Human Follicle Stimulating Hormone Produced by Chinese Hamster Ovary Cells

Journal of microbiology and biotechnology, v.15 no.2, 2005년, pp.395 - 402  

NA KYU HEUM (Research Laboratories, Dong-A Pharmaceutical Co., Ltd., Drug Targeting Laboratory, College of Pharmacy, SungKyunKwan University) ,  KIM SEUNG CHUL (Research Laboratories, Dong-A Pharmaceutical Co., Ltd.) ,  SEO KWANG SEOK (Research Laboratories, Dong-A Pharmaceutical Co., Ltd.) ,  LEE SUNG HEE (Research Laboratories, Dong-A Pharmaceutical Co., Ltd.) ,  KIM WON BAE (Research Laboratories, Dong-A Pharmaceutical Co., Ltd.) ,  LEE KANG CHOON (Drug Targeting Laboratory, College of Pharmacy, SungKyunKwan University)

Abstract AI-Helper 아이콘AI-Helper

Biologically active recombinant human follicle stimulating hormone (rhFSH) was produced in Chinese hamster ovary cells and purified by a series of chromatographic steps. The chromatographic steps included anion-exchange chromatography (DEAE Sepharose F/F, Q Sepharose F/F), hydrophobic interaction ch...

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