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Pycnogenol Supplementation Retards Immune Dysfunction in Murine AIDS (MAIDS) After LP-BM5 Leukemia Virus Infection by Modulating Cytokine Secretion

Journal of food science and nutrition, v.10 no.2, 2005년, pp.161 - 166  

Lee, Jeong-Min (Department of Food and Life Sciences, Nambu University) ,  Park, Kun-Young (Department of Food and Nutrition, Pusan National University) ,  Hwang, Kwon-Tack (Department of Food and Life Sciences, Nambu University) ,  Watson, Ronald R. (Division of Health Promotion Sciences, Mel and Enid Zuckerman, College of Public Health, University of Arizona)

Abstract AI-Helper 아이콘AI-Helper

We investigated the effect of pycnogenol (PYC) supplementation on retarding the immune dysfunction of CS7BL/6 mice after murine AIDS (MAIDS) development. Dysfunction of T and B cell mitogenesis from primary cultured splenocytes has been observed with retrovirus infection and PYC supplementation part...

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  • In our study, PYC supplementation started feeding mice at 2 weeks after murine retrovirus infection when symptoms of MAIDS already developed. This study would inform of how PYC supplementation affects immune system in MAIDS. The function of T and B cell was more active than that of unsupplemented group.
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