$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Terrein, a Melanin Biosynthesis Inhibitor, from Penicillium sp. 20135 원문보기

Journal of microbiology and biotechnology, v.15 no.4, 2005년, pp.891 - 894  

KIM WON-GON (Korea Research Institute of Bioscience and Biotechnology) ,  RYOO IN-JA (Korea Research Institute of Bioscience and Biotechnology) ,  PARK SEO-HYOUNG (Department of Dermatology, Seoul National University College of Medicine) ,  KIM DONG-SEOK (Department of Dermatology, Seoul National University College of Medicine) ,  LEE SANGKU (Korea Research Institute of Bioscience and Biotechnology) ,  PARK KYOUNG-CHAN (Department of Dermatology, Seoul National University College of Medicine) ,  YOO ICK-DONG (Korea Research Institute of Bioscience and Biotechnology)

Abstract AI-Helper 아이콘AI-Helper

In the course of screening a melanin biosynthesis inhibitor, terrein, 4,5-dihydroxy-3-propenyl-2-cyclopenten-l-one, was isolated from Penicillium sp. Terrein was found to have a strong inhibitory activity on melanin formation in B 16 melanoma and melanocyte Mel-Ab cells....

주제어

참고문헌 (21)

  1. Cabanes, J., S. Chazarra, and F. Garcia-Carmona. 1994. Kojic acid, a cosmetic skin whitening agent, is a slow binding inhibitor of catecholase activity of tyrosinase. J. Pharm. Pharmacol. 46: 982-985 

  2. Dooley, T. P., R. C. Gadwood, K. Kilgore, and L. M. Thomasco. 1994. Development of an in vitro primary screen for skin depigmentation and antimelanoma agents. Skin Pharmacol. 7: 188-200 

  3. Fujimoto, N., H. Watanabe, T. Nakatani, G Roy, and A. Ito. 1998. Induction of thyroid tumors in (C57BL/6N x C3H/ N)FI mice by oral administration of kqjic acid. Food Chem. Toxicol. 36: 697 - 703 

  4. Harper, J. K., A. E. Mulgrew, J. Y. Li, D. H. Barich, G. A. Strobel, and D. M. Grant. 2001. Characterization of stereochemistry and molecular conformation using solid-state NMR tensors. J. Am. Chem. Soc. 123: 98379842 

  5. Hearing, V. J. and M. Jimenez. 1989. Analysis of mammalian pigmentation at the molecular level. Pigment Cell Res. 2: 75-85 

  6. Hyeon, J. D., K. D. Park, S. H. Kim, K. R. Kim, S. W. Choi, J. T. Kim, K. H. Choi, and J. H. Kim. 2004. Identification of Streptomyces sp. producing antibiotics against phytopathogenic fungi, and its structure. J. Microbiol. Biotechnol. 14: 212-215 

  7. Hwang, S. E., H. M. Im, D. H. Kim, H. J. Shin, D. H. Shin, J. E. Park, I. H. Jo, C. J. Kim, J. S. Yoo, J. M. Kang, D. Y. Lim, S. M. Ahn Jo, and H. J. Kwon. 2003. Isolation of Streptomyces sp. KKS65 as a producer of ${\beta}$ -amyloid aggregation inhibitor. J. Microbiol. Biotechnol. 13: 809-814 

  8. Kawakubo, J., H. Nishira, K. Aoki, and R. Shinke. 1994. Production of phenolic compounds by Aspergillus S-4 in sake cake medium and identification of terrein. Biosci. Biotech. Biochem. 57: 1208-1209 

  9. Kim, J.-P., B.-K. Kim, B.-S. Yun, J.-J. Ryoo, C.-H. Lee, I.-K. Lee, W.-G. Kim, S. Lee, Y.-R. Pyun, and I.-D. Yoo. 2003. Melanocins A, Band C, new melanin synthesis inhibitors produced by Eupenicillium shearii. I. Taxonomy, fermentation, isolation and biological properties. J. Antibiot. 56: 993-999 

  10. Kim, J.-P., B.-K. Kim, B.-S. Yun, J.-J. Ryoo, I.-K. Lee, W.-G Kim, S. Lee, Y.-R. Pyun, and I.-D. Yoo. 2003. Melanocins A, Band C, new melanin synthesis inhibitors produced by Eupenicillium shearii. I. Physico-chemical properties and structure elucidation. J. Antibiot. 56: 1000-1003 

  11. Kolb, H. C., H. Hoffinann, and R. Martin. 1990. A total synthesis of racemic and optically active terrein (trans-4,5dihydroxy-3-[( ${\beta}$ )-1-propenyl]-2-cyclopenten-I-one). Tetrahedron: Asymmetry 1: 237-250 

  12. Lim, H. Y., M. K. Kim, Y. H. Cho, J. M. Kim, Y. H. Lim, and C. H. Lee. 2004. Inhibition of cell cycle progression and induction of apoptosis in HeLa cells by HY558-1, a novel CDK inhibitor isolated from Penicilliulll. minioluteum F558. J. Microbiol. Biotechnol. 14: 978-984 

  13. Malstrom, J., C. Christophersen, A. F. Barrero, J. E. Oltra, J. Justicia, and A. Rosales. 2002. Bioactive metabolites from a marine-derived strain of the fungus Emericella variecolor. J. Nat. Prod. 65: 364-367 

  14. Mitscher, L. A., G. W. Clark III, and G. H. Bokelman. 1978. Method for the preparation of prostaglandin intermediates from a mold metabolite. U. S. Patent 4103091 (Jul. 25, 1978) 

  15. Ohguchi, K., Y. Banno, Y. Akao, and Y. Nozawa. 2004. Involvement of phospholipase D1 in melanogenesis of mouse B 16 melanoma cells. J. Biol. Chem. 279: 3408-3412 

  16. Raistrick, H. and G Smith. 1935. Biochemistry of micro.ovrddot.okirganisms. XLII. The metabolic products of Aspergillus terreus Thorn. A new mold metabolic product terrein. Biochem. J. 29: 606-611 

  17. Rhee, K. H. 2003. Purification and identification of an antifungal agent from Streptomyces sp. KH-614 antagonistic to rice blast fungus, Pyricularia oryzae. J. Microbiol. Biotechnol. 13: 984-988 

  18. Schroder, J. M. 1995. Cytokine networks in the skin. J. Invest. Dermatol. 105: 20S-24S 

  19. Spritz, R. A. and V. J. Hearing. 1994. Genetic disorders of pigmentation. Adv. Hum. Genet. 22: 1-45 

  20. Takizawa, T., K. Mitsumori, T. Tamura, M. Nasu, M. Ueda, T. Imai, and M. Hirose. 2003. Hepatocellular tumor induction in heterozygous p53-deficient CBA mice by a 26-week dietary administration of kojic acid. Toxicol. Sci. 73: 287-293 

  21. Vi, Y. S., S. H. Kim, M. W. Kim, G J. Choi, K. Y. Cho, J. K. Song, and Y. H. Lim. 2004. Antifungal activity of Streptomyces sp. against Puccinia recondite causing wheat leaf rust. J. Microbiol. Biotechnol. 14: 422-425 

저자의 다른 논문 :

관련 콘텐츠

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로