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Isolation of Candida albicans Chitin Synthase 1 Inhibitor from Streptomyces sp. A6705 and Its Characterization

Journal of microbiology and biotechnology, v.15 no.4, 2005년, pp.895 - 898  

KIM NA RAE (Laboratory of Cellular Function Modulator, Korea Research Institute of Bioscience and Biotechnology) ,  HWANG EUI IL (Bio Research Group, KT&G Central Research Institute) ,  YUN BONG SIK (Laboratory of Cellular Function Modulator, Korea Research Institute of Bioscience and Biotechnology) ,  LEE SANG HAN (Laboratory of Cellular Function Modulator, Korea Research Institute of Bioscience and Biotechnology) ,  MOON JAE SUN (Laboratory of Cellular Function Modulator, Korea Research Institute of Bioscience and Biotechnology) ,  LIM CHI HWAN (Department of Agricultural Chemistry, Graduate School, Chungnam National University) ,  LIM SE JIN (College of Pharmacy, Dongduk Women's University) ,  KIM SUNG UK (Laboratory of Cellular Function Modulator, Korea Research Institute of Bioscience and Biotechnology)

Abstract AI-Helper 아이콘AI-Helper

In the course of searching for potent chitin synthase 1 inhibitors from natural resources, Streptomyces sp. A6705 was found to exhibit potent inhibitory activity against the chitin synthase 1 from C. albicans (CaCHS1p). As a result, the inhibitor was isolated and identified using a series of chromat...

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참고문헌 (18)

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