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논문 상세정보

Abstract

The antioxidative effect of Ecklonia cava, a brown marine alga, was investigated on radical scavenging, including 1,1-diphenyl-2-picrylhydrazyl (DPPH), and hydroxyl and alkyl radicals, using an electron spin resonance (ESR) technique, and on the inhibition of $H_2O_2$-induced DNA damage using comet assay. E. cava was enzymatically hydrolyzed with five food industrial proteases (Alcalase, Flavourzyme, Kojizyme, Neutrase and Protamex) to prepare water-soluble extracts. All the proteolytic hydrolysates exhibited strong dose-dependent radical scavenging activities (above 80%) at a concentration of $2.5\;{\mu}g/mL$. Kojizyme extract (obtained by proteolytic hydrolysation of E. cava with Kojizyme) showed the highest hydroxyl radical scavenging activity of around 98%. In addition, the $H_2O_2$-induced DNA damage was determined using a comet assay, which was quantified by measuring the tail length. Reduction of DNA damage increased with increasing concentrations of Kojizyme extract from E. cava. These results indicated that E. cava has a potential as a valuable natural antioxidative source.

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이 논문을 인용한 문헌 (5)

  1. 2006. "" Food science and biotechnology, 15(2): 312~316 
  2. 2007. "" Food science and biotechnology, 16(5): 765~770 
  3. 2008. "" Food science and biotechnology, 17(4): 745~750 
  4. Seo, Joo-Young ; Kim, Kyoung-Duck ; Son, Maeng-Hyun ; Lee, Sang-Min 2010. "Growth Performance, Hematological Parameter and Fatty Acid Composition of Growing Olive Flounder (Paralichthys olivaceus) to Dietary Inclusion of Kelp Meal, Krill Meal, Garlic Powder or Citrus Meal" 한국수산과학회지 = Korean journal of fisheries and aquatic sciences, 43(5): 557~561 
  5. Kim, Kyoung-Duck ; Seo, Joo-Young ; Hong, Su-Hee ; Kim, Jeong-Ho ; Byun, Hee-Guk ; Kim, Kang-Woong ; Son, Maeng-Hyun ; Lee, Sang-Min 2011. "Effects of Dietary Inclusion of Various Additives on Growth Performance, Hematological Parameters, Fatty Acid Composition, Gene Expression and Histopathological Changes in Juvenile Olive Flounder Paralichthys olivaceus" 한국수산과학회지 = Korean journal of fisheries and aquatic sciences, 44(2): 141~148 

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