[논문]Near-Infrared Light Propagation in an Adult Head Model with Refractive Index Mismatch

Kim, Seung-Hwan; Lee, Jae-Hoon

doi:10.4218/etrij.05.0104.0056

Near-Infrared Light Propagation in an Adult Head Model with Refractive Index Mismatch 원문보기

ETRI journal, v.27 no.4, 2005년, pp.377 - 384

Kim, Seung-Hwan (Basic Research Laboratory, ETRI) , Lee, Jae-Hoon (Basic Research Laboratory, ETRI)

Abstract ▼ AI-Helper

We investigate near-infrared light (NIR) propagation in a model of an adult head using an extensive Monte Carlo (MC) simulation. The adult head model is a four-layered slab which consists of a surface layer, a cerebrospinal fluid layer, a gray-matter layer, and a white-matter layer. We study the effects of a refractive index mismatch on the model, calculating the intensity of detected light, mean flight time, and partial mean flight time of each layer for various refractive indices of the cerebrospinal fluid layer as functions of source-detector spacing. The Monte Carlo simulation shows that the refractive index mismatch presents very rich results including rapidly decaying intensity of detected light and a peak and cross-over in the partial mean flight time with source-detector spacing. We also investigate spatial sensitivity profiles at various source-detector spacings, discussing the index mismatch effect on the model.

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문제 정의

In this paper, we investigate NIR light propagation in a model of the adult head by extensive MC simulation considering the RI mismatch. The adult head model is a four layered slab which consists of a surface layer, a CSF layer, a gray-matter (GM) layer, and a white-matter (WM) layer.

가설 설정

Flowchart of MC simulation for multi-layered tissues. s: the step size of photon movement between sites of photon-tissue interaction.

제안 방법

The MC algorithm describes the local rules of photon propagation, which are expressed as probability distributions describing the step size of photon movement between sites of photon-tissue interaction and the angles of deflection in a photon’s trajectory when a scattering event occurs. In the simulation, we calculated the intensity, MFT, and PMFT in each layer of detected light as functions of SD spacing. In the simulation, the number of photons ranges from a half billion to one billion.
In this study, we performed an extensive Mc simulation of light propagation for an adult head model investigating the effects of an RI mismatch at the boundaries of the csF layer. The Mc simulation shows that the RI mismatch presents a very rich behavior of the detected light intensity, the MFT of photons, and the PMFT of photons as functions of sD spacing.
In this paper, we investigate the effects of an RI mismatch between the tissues on NIR light propagation in an adult head. To focus on the effects of the RI mismatch, we chose a simple adult head model consisting of four different homogeneous media including a surface layer, a CSF layer, a GM layer and a WM layer. The surface layer imitates the scalp and skull.

이론/모형

In this study, we used the MC algorithm for light transport in the multi-layered tissues described in [29] and [30]. The MC algorithm describes the local rules of photon propagation, which are expressed as probability distributions describing the step size of photon movement between sites of photon-tissue interaction and the angles of deflection in a photon’s trajectory when a scattering event occurs.

성능/효과

Okada and others [24] studied NIR light propagation in various models such as a three-layered slab without a CSF layer, four-layered slab with a CSF layer, four layered slab with uneven boundary between the GM and the WM, and four-layered slab with slots imitating the sulci filled with CSF. They concluded that a CSF layer significantly affects light propagation in an adult head, but the geometries of the sulci and the boundary between the GM layer and the WM layer scarcely affect the optical path.

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DOI : 10.4218/etrij.05.0104.0056 [무료]
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