Yoon, S.S.
(National Veterinary Research and Quarantine Service)
,
Bae, Y.C.
(National Veterinary Research and Quarantine Service)
,
Lee, K.H.
(National Veterinary Research and Quarantine Service)
,
Han, B.
(College of Veterinary Medicine, Seoul National University)
,
Han, H.R.
(College of Veterinary Medicine, Seoul National University)
The frequency and distribution of lymphoma caused by bovine leukemia virus (BLV) infection in various organs were investigated. Lymphoma samples were obtained from slaughtered cattle or from cattle submitted to the National Veterinary Research and Quarantine Service, Korea. Thirty female Holstein-Fr...
The frequency and distribution of lymphoma caused by bovine leukemia virus (BLV) infection in various organs were investigated. Lymphoma samples were obtained from slaughtered cattle or from cattle submitted to the National Veterinary Research and Quarantine Service, Korea. Thirty female Holstein-Friesian dairy cattle aged over three years with the BLV-associated lymphoma were studied. None of the Korean native cattle (Hanwoo) had lymphoma in this study however. Lymphoma tissues were gray to pink in color, soft in consistency, and bulged from the cut surface. In advanced lymphoma tissues, there was great variety in the appearance of involved structures due to hemorrhage, necrosis, and/or calcification. Neoplastic tissues were observed in lymph nodes in all lymphoma cases. Intestine (96.4%), heart (88.9%), stomach (73.1%), and diaphragm (62.5%) were frequently involved with lymphoma. However, there was no lymphoma detected in liver. Large neoplastic masses, sometimes reaching the size of over 20 cm, were found in the abdominal cavities. It is suggested that metastasis of lymphomas occurs mainly via lymph based on gross observations; neoplasia may have been initiated in the serosal surface of the lung, heart, peritoneum, and numerous hollow organs in the abdominal cavity. Also many organs in the abdominal and thoracic cavity were affected by neoplastic tissues simultaneously. Characteristics observed in this study could be used as criteria to differentiate BLV-associated lymphoma from other nodular lesions in the slaughterhouse and as fundamental data to make clear the mechanism of metastasis or pathogenesis of EBL.
The frequency and distribution of lymphoma caused by bovine leukemia virus (BLV) infection in various organs were investigated. Lymphoma samples were obtained from slaughtered cattle or from cattle submitted to the National Veterinary Research and Quarantine Service, Korea. Thirty female Holstein-Friesian dairy cattle aged over three years with the BLV-associated lymphoma were studied. None of the Korean native cattle (Hanwoo) had lymphoma in this study however. Lymphoma tissues were gray to pink in color, soft in consistency, and bulged from the cut surface. In advanced lymphoma tissues, there was great variety in the appearance of involved structures due to hemorrhage, necrosis, and/or calcification. Neoplastic tissues were observed in lymph nodes in all lymphoma cases. Intestine (96.4%), heart (88.9%), stomach (73.1%), and diaphragm (62.5%) were frequently involved with lymphoma. However, there was no lymphoma detected in liver. Large neoplastic masses, sometimes reaching the size of over 20 cm, were found in the abdominal cavities. It is suggested that metastasis of lymphomas occurs mainly via lymph based on gross observations; neoplasia may have been initiated in the serosal surface of the lung, heart, peritoneum, and numerous hollow organs in the abdominal cavity. Also many organs in the abdominal and thoracic cavity were affected by neoplastic tissues simultaneously. Characteristics observed in this study could be used as criteria to differentiate BLV-associated lymphoma from other nodular lesions in the slaughterhouse and as fundamental data to make clear the mechanism of metastasis or pathogenesis of EBL.
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문제 정의
, 1982), and the reports on characteristics oflymphoma in the naturally BLV-infected cattle are limited in Korea. It is the purpose of this study to assess the frequency and distribution oflymphoma in the BLV- infected cattle.
, 1982), and the reports on characteristics oflymphoma in the naturally BLV-infected cattle are limited in Korea. It is the purpose of this study to assess the frequency and distribution oflymphoma in the BLV- infected cattle.
대상 데이터
Samples were obtained from slaughtered cattle, and from cattle submitted for disease diagnosis to the Pathology division, National Veterinary Research Quarantine Service (NVRQS), Korea. Four lymphoma-suspected samples were collected at NVRQS diagnostic laboratory from January 1993 to June 2004 and 43 samples at abattoir from January 2002 to June 2004.
후속연구
Gross appearances and frequency of organ involvement observed in various organs could be used as criteria to detect BLV-associated lymphoma in the slaughter house and to differentiate grossly EBL from SBL. It is likely for future research to clarify the properties of genetic resistance ofthe Korean native cattle (HanWoo) to BLV infection.
Gross appearances and frequency of organ involvement observed in various organs could be used as criteria to detect BLV-associated lymphoma in the slaughter house and to differentiate grossly EBL from SBL. It is likely for future research to clarify the properties of genetic resistance ofthe Korean native cattle (HanWoo) to BLV infection.
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