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논문 상세정보

초록

DPPH radical 소거 활성은 추출물의 농도가 증가함에 따라 높게 나타났으며, 추출용매별 radical 소거활성은 거의 유사한 경향으로 나타났다. 프로폴리스 추출물의 첨가농도가 증가함에 따라 환원력이 증가하는 경향을 나타내었으며, 특히 50% 에탄을 추출물이 가장 강한 환원력을 나타내었다. 유지에 프로폴리스 추출물을 첨가하여 과산화물가, TBA가 및 산가를 측정한 결과 95% 에탄을 추출물이 가장 높은 산패 억제능을 나타내었다. 프로폴리스 추출물의 농도가 증가함에 따라 아질산염 소거 활성이 증가하였으며, 물추출물 500 $\mu$g을 첨가하였을 때 90%의 가장 높은 활성을 나타내었다. 프로폴리스의 각종 추출물을 이용하여 항균활성을 측정한 결과 50%에탄을 추출물에서 가장 높은 활성을 나타내었으며, 특히 Bacillus subtilis균과 Bacillus cereus균과 같은 그램 양성균에서 높은 활성을 나타내었다. 프로폴리스의 각종 추출물을 이용하여 1, 10 및 100 $\mu$g/mL 농도로 각각 첨가한 후 A549(폐암세포)에 대한 in vitro에서의 세포독성을 조사한 결과 70% 에탄을 추출물 100 $\mu$g/mL를 첨가하였을 때 62.63%의 가장 강한 세포독성을 나타내었으며,95% 에탄올 추출물, 물추출물 및 50% 에탄을 추출물 순으로 나타났다.

Abstract

The scavenging effects of four extracts on the DPPH radical were increased with increasing amount of extract. However, these effects were not statistically significant. The reducing power of the extracts is increased as the amount of extract is increased. To compare reducing powers of various solvent extracts, 50% ethanol extract showed the highest reducing power. The various solvent extracts were also capable of scavenging nitrite in a manner dependent on concentration. They exhibited scavenging effects 90% on nitrite at the dose 500 p.g of water extract from propolis. The propolis extract significantly inhibited all the microorganisms tested, showing the largest inhibitory zone for Bacillus subtilis and Bacillus cereus. The 70% ethanol extract from propolis exhibited the strongest inhibitory effect on A549. The inhibitory effect of four extracts showed in that order 70% ethanol extract>95% ethanol extract>water extract>50% ethanol extract.

저자의 다른 논문

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이 논문을 인용한 문헌 (12)

  1. 2006. "" Food science and biotechnology, 15(3): 482~484 
  2. Park, Eun-Ryong ; Lee, Sun-Kyu ; Hwang, Hye-Shin ; Mun, Chun-Sun ; Gwak, In-Shin ; Kim, Ok-Hee ; Lee, Kwang-Ho 2008. "Monitoring of Natural Preservative Levels in Food Products" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 37(12): 1640~1646 
  3. Kim, Gwang-Woo ; Kim, Ga-Hyeon ; Kim, Jeong-Sik ; An, Hyo-Yeong ; Hu, Gil-Won ; Park, In-Suk ; Kim, Ok-Seon ; Cho, Soon-Yeong 2008. "Quality Characteristics of Fried Fish Paste of Alaska Pollack Meat Paste Added with Propolis" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 37(4): 485~489 
  4. Park, Heon-Kuk ; Kim, Sang-Bum ; Shim, Chang-Hwan 2008. "Antimicrobial Activity of Water Soluble Propolis" 한국식품영양학회지 = The Korean journal of food and nutrition, 21(1): 15~21 
  5. Lee, Soo-Jung ; Cha, Ji-Young ; Shin, Jung-Hye ; Chung, Mi-Ja ; Sung, Nak-Ju 2008. "Antioxidant Effect of Wa-song (Orostachys japonicus A. Berger) Extracts on Edible Oil and Fat" 생명과학회지 = Journal of life science, 18(8): 1106~1114 
  6. Kim, Seong-Ho ; Kim, In-Ho ; Kang, Bok-Hee ; Lee, Kyung-Hee ; Lee, Sang-Han ; Lee, Dong-Sun ; Cho, So-Mi K. ; Hur, Sang-Sun ; Kwon, Taeg-Kyu ; Lee, Jin-Man 2009. "Optimization of Ethanol Extraction Conditions from Propolis (a Bee Product) Using Response Surface Methodology" 한국식품저장유통학회지 = Korean journal of food preservation, 16(6): 908~914 
  7. Lee, Soo-Jung ; Shin, Jung-Hye ; Seo, Jong-Kwon ; Sung, Nak-Ju 2009. "Effect of Wa-song(Orostachys japonicus A. Berger) Extract on the Oxidative Stability of Edible Oil During its Heating" 한국식품위생안전성학회지 = Journal of food hygiene and safety, 24(1): 12~18 
  8. Jang, Il-Woong ; Park, Jeong-Seob ; Kwon, Hyoung-Cheol ; Jung, Mun-Yhung ; Choi, Dong-Seong 2009. "Antimutagenic and Antibacterial Activities of Korean and American Propolis" 한국식품과학회지 = Korean journal of food science and technology, 41(6): 694~699 
  9. 2009. "" Food science and biotechnology, 18(4): 1042~1045 
  10. Jeong, Chang-Ho ; Shin, Chang-Sik ; Bae, Young-Il ; Shim, Ki-Hwan 2010. "Antioxidant Activities of Ethanol and Water Extracts from Propolis" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 39(12): 1725~1730 
  11. Chang, Min-Sun ; Park, Mi-Ji ; Jeong, Moon-Cheol ; Kim, Dong-Man ; Kim, Gun-Hee 2012. "Antioxidative Activities and Antibrowning Effects of Green Tea Extracts and Propolis" 한국식품조리과학회지 = Korean Journal of Food & Cookery Science, 28(3): 319~326 
  12. Kim, Sang-A ; Chung, Hyun-Jung 2013. "Antimicrobial Effects of Propolis against Oral Microorganisms" 한국식품과학회지 = Korean journal of food science and technology, 45(3): 370~375 

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