$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Fungicidal Effect of Resveratrol on Human Infectious Fungi 원문보기

Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.28 no.5, 2005년, pp.557 - 560  

Jung, Hyun-Jun (Department of Microbiology, College of Natural Sciences, Kyungpook National University) ,  Hwang, In-Ah (Department of Microbiology, College of Natural Sciences, Kyungpook National University) ,  Sung, Woo-Sang (Department of Microbiology, College of Natural Sciences, Kyungpook National University) ,  Kang, Hyun-Gu (Department of Microbiology, College of Natural Sciences, Kyungpook National University) ,  Kang, Beom-Sik (School of Life Science, College of Natural Sciences, Kyungpook National University) ,  Seu, Young-Bae (Department of Microbiology, College of Natural Sciences, Kyungpook National University) ,  Lee, Dong-Gun (Department of Microbiology, College of Natural Sciences, Kyungpook National University)

Abstract ▼ AI-Helper 아이콘AI-Helper

Resveratrol, a phenolic antioxidant found in grapes, has been known to mediate various biological activities on the human body. In the present study, we tested the antifungal a ctivity of resveratrol against human pathogenic fungi before carrying out further studies to elucidate the antifungal mecha...

주제어

#Resveratrol   #trans-3,5,4'-Trihydroxystilbene   #Phenolic antioxidant   #Fungicidal activity   #Hemolytic effect  

AI 본문요약
AI-Helper 아이콘 AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

제안 방법

  • In order to confirm that fungicidal effect of resveratrol does brings abo녀t morphological changes in fungal cells, we examined the morphology of C. albicans cells in the presence of resveratrol by scanning electron microscopy (SEM). As shown in Fig.

대상 데이터

  • Stock solutions of resveratrol and amphotericin B were prepared in dimethyl sulfoxide (DMSO) and stored at -20℃. Aspergillus flavus (KCTC 1375), Saccharomyces cerevisiae (KCTC 7296) and Trichosporon beigelii (KCTC 7707) were obtained from the Korean Collection for Type Cultures (KCTC), at the Korea Research Institute of Bioscience Biotechnology (KRIBB), Taejon, Korea. Candida a/bicans (TIMM 1768) was obtained from the Center for Academic Societies, Osaka, Japan.
  • 2). The samples were dehydrated with a graded ethanol series (50%, 70%, 90%, 95%, and 100% ethanol). After lyophilization and gold coating, the samples were examined on a HIIACHl S-2400 (Tokyo, Japan) (Lee et al.
본문요약 정보가 도움이 되었나요?

참고문헌 (17)

  1. Adams, M. L. and Kwon, G. S., Relative aggregation state and hemolytic activity of amphotericin B encapsulated by poly(ethylene oxide)-block-poly(N-hexyl-L-aspartamide)-acyl conjugate micelles: effects of acyl chain length. J. Controlled Release, 87, 23-32 (2003) 

    상세보기 crossref

  2. Clement, M. V., Hirpara, J. L., Chawdhury, S. H., and Pervaiz, S., Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumor cells. Blood, 92, 996-1002 (1998) 

    상세보기

  3. Daroch, F., Hoeneisen, M., Gonzalez, C. L., Kawaguchi, F., Salgado, F., Solar, H., and Garcia, A., In vitro antibacterial activity of Chilean red wines against Helicobacter pylori. Microbios, 104, 79-85 (2001) 

    상세보기

  4. ElAttar, T. M. and Virji, A. S., Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation. Anticancer Drugs, 10, 187-193 (1999) 

    상세보기 crossref

  5. Filip, V., Plockova, M., Smidrkal, J., Spickova, Z., Melzoch, K., and Schmidt, S., Resveratrol and its antioxidant and antimicrobial effectiveness. Food Chem., 83, 585-593 (2003) 

    상세보기 crossref

  6. Gronbaek, M., Deis, A., Sorensen, T. I., Becker, U., Schnohr, P., and Jensen, G., Mortalilty associated with moderate intakes of wine, beer, or spirits. Br. Med. J., 310, 1165-1169 (1995) 

    상세보기 crossref

  7. Hoos, G. and Blaich, R., Influence of resveratrol on germination of conidia and mycelial growth of Botrytis cinerea and Phomopsis riticola. J. Phytopathol., 129, 102-110 (1990) 

    상세보기 crossref

  8. Hsieh, T. and Wu, J. M., Differential effects on growth, cell cycle arrest, and induction of apoptosis by resveratrol in human prostate cancer cell lines. Exp. Cell Res., 249, 109-115 (1999) 

    상세보기 crossref

  9. Jahn, B., Martin, E., Stueben, A., and Bhakdi, S., Susceptibility testing of Candida albicans and Aspergillus species by a simple microtiter menadione-augmented 3-(4,5-dimethyl-2- thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay. J. Clin. Microbial., 33, 661-667 (1995) 

  10. Jang, M., Cai, L., Udeani, G. O., Slowing, K. V., Thomas, C. F., Beecher, C. W. W., Fong, H. H. S., Farnsworth, N. R., Kinghorn, A. D., Mehta, R. G., Moon, R. C., and Pezzuto. J. M., Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science, 275, 218-220 (1997) 

    상세보기 crossref

  11. Klepser, M. E., Ernst, E. J., Lewis, R. E., Ernst, M. E., and Pfaller, M. A., Influence of Test Conditions on Antifungal Time-Kill Curve Results: Proposal for Standardized Methods. Antimicrob. Agents Chemother., 42, 1207-1212 (1998) 

    상세보기

  12. Lee, D. G., Kim, D. ？H., Park, Y., Kim, H. K., Kim, H. N., Shin, Y. K., Choi, C. H., and Hahm, K. ？S., Fungicidal effect of antimicrobial peptide, PMAP-23, isolated from porcine myeloid against Candida albicans. Biochem. Biophys. Res. Commun., 282, 570-574 (2001) 

    상세보기 crossref

  13. Lee, D. G., Park, Y., Kim, H. N., Kim, H. K., Kim, P. I., Choi, B. H., and Hahm, K. -S., Antifungal Mechanism of an Antimicrobial Peptide, HP(2-20), Derived from N-Terminus of Helicobacter pylori Ribosomal Protein L1 against Candida albicans. Biochem. Biophys. Res. Commun., 293, 231-238 (2002) 

    상세보기 crossref

  14. Pace-Asciak, C. R., Hahn, S., Diamandis, E. P., Soleas, G., and Goldberg, D. M., The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: Implications for protection against coronary heart disease. Clin. Chim. Acta, 235, 207-219 (1995) 

    상세보기 crossref

  15. Rotondo, S., Rajtar, G., Manarini, S., Celardo, A., Rotillo, D., de Gaetano, Evangelista, V., and Cerletti, C., Effect of transresveratrol, a natural polyphenolic component on human polymorphonuclear leukocyte function. Br. J. Pharmacol., 123(8), 1691-1699 (1998) 

    상세보기 crossref

  16. Tegos, G., Stermitz, F. R., Lomovskaya, O., and Lewis, K., Multidrug Pump Inhibitors Uncover Remarkable Activity of Plant Antimicrobials. Antimicrob. Agents Chemother. 46, 3133-3141 (2002) 

    상세보기 crossref

  17. Yoon, S. -H., Kim, Y. -S., Ghim, S. -Y., Song, B. -H., and Bae, Y. -S., Inhibition of protein kinase CK activity by resveratrol, a natural compound in red wine and grapes. Life Sci., 71, 2145-2152 (2002) 

    상세보기 crossref

저자의 다른 논문 :

관련 콘텐츠

오픈액세스(OA) 유형

FREE

Free Access. 출판사/학술단체 등이 허락한 무료 공개 사이트를 통해 자유로운 이용이 가능한 논문

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로