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논문 상세정보

Abstract

The chromatographic separation of the hexane soluble fraction of the methanol extract of the aerial parts of Solidago virga-aurea var. gigantea Mo. (Compositae) led to the isolation of a new benzylbenzoate (1) together with four known benzylbenzoates (2-5). Their structures were determined as 2-methoxybenzyl-2-hydroxybenzoate (1), benzyl-2-hydroxy-6-methoxy­benzoate (2), 2-methoxybenzyl-2,6-dimethoxybenzoate (3), 2-methoxybenzyl-2-methoxy-6­hydroxybenzoate (4), and benzyl-2,6-dimethoxybenzoate (5). Their structures were established by spectroscopic methods. Biological effects of compounds, 1 and 2, were investigated in vitro usingherapeutic agents by stimulating macrophage functions, with potential use in the treat­ mouse peritoneal macrophages. The benzylbenzoates (1 and 2) could serve as immunotherapeutic agents by stimulating macrophage functions, with potential use in the treatment of infectious diseases.

참고문헌 (13)

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이 논문을 인용한 문헌 (2)

  1. Park, Hee-Juhn ; Nugroho, Agung ; Lee, Jin-Ha ; Kim, Jong-Dae ; Kim, Won-Bae ; Lee, Kang-Ro ; Choi, Jae-Sue 2009. "HPLC Analysis of Caffeoylquinic Acids in the Extract of Cacalia firma and Peroxynitrite Scavenging Effect" 생약학회지, 40(4): 365~369 
  2. 2009. "" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, 32(10): 1361~1367 

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