• 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보


The chromatographic separation of the hexane soluble fraction of the methanol extract of the aerial parts of Solidago virga-aurea var. gigantea Mo. (Compositae) led to the isolation of a new benzylbenzoate (1) together with four known benzylbenzoates (2-5). Their structures were determined as 2-methoxybenzyl-2-hydroxybenzoate (1), benzyl-2-hydroxy-6-methoxy­benzoate (2), 2-methoxybenzyl-2,6-dimethoxybenzoate (3), 2-methoxybenzyl-2-methoxy-6­hydroxybenzoate (4), and benzyl-2,6-dimethoxybenzoate (5). Their structures were established by spectroscopic methods. Biological effects of compounds, 1 and 2, were investigated in vitro usingherapeutic agents by stimulating macrophage functions, with potential use in the treat­ mouse peritoneal macrophages. The benzylbenzoates (1 and 2) could serve as immunotherapeutic agents by stimulating macrophage functions, with potential use in the treatment of infectious diseases.

참고문헌 (13)

  1. Lu, T., Vargas, D., and Fisher, N. H., Sesquiterpenes from Brintonia discoidea. Phytochemistry, 34, 737-742 (1993) 
  2. Singh, P., Jain, R., and Krishna, V., Benzyl-2,6-dimethoxy and benzyl-2,3,5,6-tetramethoxybenzoates from Blainvillea latifolia Linn. Nat. Prod. Sci., 4, 42-44 (1997) 
  3. Flick, D. A. and Gifford, G. E., Comparison of in vitro cell cytotoxicity assays for tumor necrosis factor. J. Immunol. Methods, 68, 167-175 (1984) 
  4. Anthonsen, T. and Gudrun, B., The diterpenoids of some Solidago species. Acta. Chem. Scan., 25, 1924-1925 (1971) 
  5. Moon, E. Y. and Pyo, S., Aflatoxin B(1) inhibits CD14-mediated nitric oxide production in murine peritoneal macrophages. Int. J . Immunopharmacol., 22, 237-246 (2000) 
  6. Lee, C. B., Illustrated Flora of Korea. Hyangmoonsa, Seoul, pp. 735 (1979) 
  7. Keller, R., Keist, R., and Frei, K., Lymphokines and bacteria that induce tumoricidal activity, trigger a different secretory response in macrophages. Eur. J. Immunol., 20, 695-698 (1990) 
  8. Sung, J. H., Lee, J. O., Son, J. K., Park, N. S., Kim, J. G., and Moon, D. C., Cytotoxic constituents from Solidago virgaaurea var. gigantea MIQ. Arch. Pharm. Res., 22, 633-637 (1999) 
  9. Kodpinid, M., Sadavongvivad, C., Thebtaranonth, C., and Thebtaranonth, Y., Benzyl benzoates from the root of Uvaria purpurea. Phytochemistry, 23, 199-200 (1984) 
  10. Son, E. W., Cho, C. K., Rhee, D. K., and Pyo, S., Inhibition of gamma-irradiation induced adhesion molecules and NO production by alginate in human endothelial cells. Arch. Pharm. Res., 24(5), 466-471 (2001) 
  11. Moon, E. Y., Rhee, D. K., and Pyo, S., Inhibition of various functions in murine peritoneal macrophages by aflatoxin B1 exposure in vivo. Int. J. Immunopharmacol., 21, 47-58 (1999) 
  12. Hibbs, J. B., Taintor, R. R., and Vavrin, Z., Macrophage cytotoxicity: role for L-arginine deiminase and imino nitrogen oxidation to nitrite. Science, 235, 473-476 (1987) 
  13. Sone, S. and Key, M. E., Antitumor and phagocytic activities of rat alveolar macrophage subpopulations separated on a discontinuous gradient of bovine serum albumin. J. Biol. Resonse. Mod., 5, 595-603 (1986) 

이 논문을 인용한 문헌 (2)

  1. Park, Hee-Juhn ; Nugroho, Agung ; Lee, Jin-Ha ; Kim, Jong-Dae ; Kim, Won-Bae ; Lee, Kang-Ro ; Choi, Jae-Sue 2009. "HPLC Analysis of Caffeoylquinic Acids in the Extract of Cacalia firma and Peroxynitrite Scavenging Effect" 생약학회지, 40(4): 365~369 
  2. 2009. "" Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, 32(10): 1361~1367 


원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일