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Preparation of Electrospun Oxidized Cellulose Mats and Their in vitro Degradation Behavior

Macromolecular research v.13 no.1 , 2005년, pp.62 - 67  
Khil Myung Seob (Department of Textile Engineering, Chonbuk National University ) ;  Kim Hak Yong ( Department of Textile Engineering, Chonbuk National University ) ;  Kang Young Sic ( Department of Textile Engineering, Chonbuk National University ) ;  Bang Ho Ju ( Department of Textile Engineering, Chonbuk National University ) ;  Lee Douk Rae ( Department of Textile Engineering, Chonbuk National University ) ;  Doo Jae Kyun ( Department of General Gynecology and Obstetrics med. School, Chonbuk National University)
Abstract

This paper investigated the effect of biodegradation behavior on the oxidation of cellulose nanofiber mats. The cellulose mats were produced through electro spinning. The diameter of an electrospun fiber varied from 90 to 240 nm depending on the electrospinning parameters, such as the solution concentration, needle diameter, and rotation speed of a grounded collector. Oxidized cellulose (OC).mats containing different carboxyl contents were prepared using $NO_2$ as an oxidant. The total carboxyl content of the cellulose nanofiber mats obtained after oxidation for 20 h was $20.6\%$. The corresponding carboxyl content was important from a commercial point of view because OC containing $16-24\%$ carboxyl content are used widely in the medical field as a form of powder or knitted fabric. Degradation tests of the OC mats were performed at $37^{\circ}C$ in phosphate-buffered saline (pH 7.4). Microscopy techniques were introduced to study the morphological properties and the degradation behavior of the OC mats. Morphological changes of the mats were visualized using optical microscopy. Within 4 days of exposure to PBS, the weight loss of the OC mats was $>90\%$.

주제어

#electrospun oxidized cellulose mats   #electrospinning, carboxyl content   #swelling   #degradation behavior  

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길명섭(19) Kim, Hak-Yong(111) 방호주(2) 이덕래(105)

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이 논문을 인용한 문헌 (1)

  1. 2008. "" Macromolecular research, 16(5): 396~398 

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