$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Abstract AI-Helper 아이콘AI-Helper

Free radicals and reactive oxygen species (ROS) caused by UV exposure or other environmental factors are critical players in cellular damage and aging. In order to develop a new antiphotoaging agent, this work focused on the antioxidant effects of the extract of tinged autumnal leaves of Acer palmat...

주제어

AI 본문요약
AI-Helper 아이콘 AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

가설 설정

  • 4. A: The effects of vitexin on the production of intracellular reactive oxygen species (ROS) in human dermal fibroblasts (HDFs). HDFs were incubated with 4 μM CM-H2DCFDA for 20 min, and irradiated by UVB 20 mJ/cm2.
  • In this study, we isolated vitexin from tinged autumnal leaves of A. palmatum and investigated its anti-oxidative properties.
본문요약 정보가 도움이 되었나요?

참고문헌 (38)

  1. Afitlhile, M. M., Dent, R. M., and Cowan, A. K., Changes in carotenoid composition in senescing leaves of Hordeum vulgare L. cv. Dyan. J. Plant Physiol., 142, 4349 (1993) 

  2. Aritomi, M., Chemical constituents in Aceraceous plants. 1. Flavonoid constituents in the leaves of Acer palmatum Thunberg. Yakugaku Zasshi, 83, 737-740 (1963) 

  3. Aritomi, M., Chemical constituents in Aceraceous plants. 3. Flavonoid constituents in leaves of Acer cissifolium K. Koch. Chem. Pharm. Bull., 12, 841-843 (1964) 

  4. Bandoniene, D. and Murkovic, M., On-line HPLC-DPPH screening method for evaluation of radical scavenging phenols extracted from apples (Malus domestica L.). J. Agric. Food Chem., 50, 2482-2487 (2002) 

  5. Bestwick, C. S. and Milne, L., Quercetin modifies reactive oxygen levels but exerts only partial protection against oxidative stress within HL-60 cells. Biochim. Biophys. Acta, 1528, 48-59 (2001) 

  6. Blois, M. S., Antioxidant determinations by the use of a stable free radical. Nature, 181, 1199-1200 (1958) 

  7. Bonina, F., Puglia, C., Ventura, D., Aquino, R., Tortora, S., Sacchi, A., Saija, A., Tomaino, A., Pellegrino, M. L., and de Capariis P., In vitro antioxidant and in vivo photoprotective effects of a lyophilized extract of Capparis spinosa L. buds. J. Cosmet. Sci., 53, 321-335 (2002) 

  8. Bors, W. and Michel, C., Chemistry of the antioxidant effect of polyphenols. Ann. N. Y. Acad. Sci., 957, 57-69 (2002) 

  9. Cathcart, R., Schwiers, E., and Ames, B. N., Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay. Anal. Biochem., 134, 111-116 (1983) 

  10. Dauborn, B. and Brueggemann, W., A spontaneous point mutation in rubisco large subunit gene impairing holoenzyme assemblyrenders the IV beta plastome mutant of Oenothera extremely light and chilling sensitive. Physiol. Plant, 104, 116-124 (1998) 

  11. Feild, T. S., Lee, D. W., and Holbrook, N. M., Why leaves turn red in autumn. The role of anthocyanins in senescing leaves of red-osier dogwood, Plant Physiol., 127, 566-574 (2001) 

  12. Furuno, K., Akasako, T., and Sugihara, N., The contribution of the pyrogallol moiety to the superoxide radical scavenging activity of flavonoids. Biol. Pharm. Bull., 25, 19-23 (2002) 

  13. Gaitan, E., Cooksey, R. C., Legan, J., and Lindsay, R. H., Antithyroid effects in vivo and in vitro of vitexin : a Cglycosylflavone in millet. J. Clin. Endocrinol. Metab., 80, 1144-1147 (1995) 

  14. Greenham, J., Harborne, J. B., and Williams, C. A., Identification of lipophilic flavones and flavonols by comparative HPLC, TLC, and UV spectral analysis. Phytochem. Anal., 14, 100-118 (2003) 

  15. Ham, I. H., Oh, I. S., Whang, W. K., and Kim I. H., Pharmacoconstituents of Korean cultivated Rhubarb leaves-the flavonoids from leaves. Yakhak Hoeji, 38, 469-475 (1994) 

  16. Harborne, J. B., Nature, Distribution and function of plant flavonoids. Prog. Clin. Biol. Res., 213, 15-24 (1986) 

  17. Harman, D., Role of free radical reactions in aging and disease. J. Geriat. Dermatol., 5, 114-127 (1997) 

  18. Katiyar, S. K., Afaq, F., Perex, A., and Mukhtar, H., Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress. Carcinogenesis, 22, 287-294 (2001) 

  19. Khettab, N., Amory, M. C., Brigand, G., Bousquet, B., and Combre, A., Photoprotective effect of vitamins A and E on polyamine and oxygenated free radical metabolism in hairless mouse epidermis. Biochimie, 70, 1709-1713 (1988) 

  20. LeBel, C. P., Ischiropoulos, H., and Bondy, S. C., Evaluation of the probe 2,7-dichlorofluorescein as an indicator of reactive oxygen species formation and oxidative stress. Chem. Res. Toxicol., 5, 227-231 (1992) 

  21. Lee, B. C., Bae, J. T., Pyo, H. B., Choe, T. B., Kim, S. W., Hwang, H. J., and Yun, J. W., Biological activities of the polysaccharides produced from submerged culture of the edible Basidiomycete Grifola Frondosa. Enzyme Microb. Technol., 6274, 1-8 (2003) 

  22. Mathews-Roth, M. M., Carotenoid pigment administration and the delay in development of UVB-induced tumors. Photochem. Photobiol., 42, 35-38 (1983) 

  23. Middleton, E. Jr., Kandaswami, C., and Theoharides, T. C., The effects of plant flavonoids on mammalian cells: Implications for inflammation, heart disease, and cancer. Pharmacol. Rev., 52, 673-751 (2000) 

  24. Nijveldt, R. J., Nood, E., Hoorn, D. EC, Boelens, P. G., Norren, K., and Leeuwen, P.AM, Flavonoids: a review of probable mechanisms of action and potential applications. Am. J. Clin. Nutr., 74, 418-425 (2001) 

  25. Norins, A. L., Free radical formation in the skin following exposure to ultraviolet light. J. Invest. Dermatol., 39, 445-448 (1962) 

  26. Oh, I. S., Whang, W. K., and Kim, I. H., Constituents of Crataegus pinnatifida val. psilosa Leaves (II) Flavonoids from BuOH fraction. Arch. Pharm. Res., 17, 314-317 (1994) 

  27. Prabhakar, M. C., Bano, H., Kumar, I., Shamsi, M. A., and Khan, M. S. Y., Pharmacological investigations on vitexin. Planta medica, 43, 396-403 (1981) 

  28. Riipi, M., Ossipov V., Lempa, K., Haukioja, E., Koricheva, J., Ossipova, S., and Pihlaja, K., Seasonal changes in birch leaf chemistry: are there trade-offs between leaf growth and accumulation of phenolics? Oecologia, 130, 380-390 (2002) 

  29. Ryoo, Y. W., Suh, S. I., Mun, K. C., Kim, B. C., and Lee, K. S., The effects of the melatonin on ultraviolet-B irradiated cultured dermal fibroblasts. J. Dermatol. Sci., 27, 162-169 (2001) 

  30. Savini, I., DAngelo, I., Ranalli, M., Melino, G., and Avigliano, L., Ascorbic acid maintenance in HaCaT cells prevents radical formation and apoptosis by UVB. Free Radic. Biol. Med., 26, 1172-1180 (1999) 

  31. Seo, S. Y., Kim, E. Y., Kim, H., and Gwang, B. J., Neuroprotective effect of high glucose agains NMDA, free radical and oxygen-glucose deprivation through enhanced mitochondrial potentials. J. Neurosci., 19, 8849-8855 (1999) 

  32. Shibamoto, T., Sulfur-containing heterocyclic compounds with antioxidative activity. Am. Chem. Soc., 564, 247-256 (1994) 

  33. Tampo, Y., Kotamraju, S., Chitambar, C. R., Kalivendi, S. V., Keszler, A., Joseph, J., and Kalyanaraman, B., Oxidative stress-induced iron signaling is responsible for peroxidedependent oxidation of dichlorodihydrofluorescein in endothelial cells. Circ. Res., 92, 56-63 (2003) 

  34. Tobi, S. E., Gilbert, M., Paul, N., and McMillan, T. J., The green tea polyphenol, epigallocatechin-3-gallate, protects against the oxidative cellular and genotoxic damage of UVA radiation. Int. J. Cancer, 102, 439-444 (2002) 

  35. Trayner, I. D., Rayner, A. P., Freeamn, G. E., and Farzaneh, F., Quantitative multiwell myeloid differentiation assay using dichlorodihydrofluorescein diacetate ( $H_2DCFDA$ ) or dihydrorhodamine 123 ( $H_2R123$ ). J. Immunol. Methods, 186, 275-284 (1995) 

  36. Yoo, S. W., Kim, J. S., Kang, S. S., Son, K. H., Chang, H. W., Kim, H. P., Bae, K. H., and Lee, C. O., Constituents of the fruits and leaves of Euodia danielli. Arch. Pharm. Res., 25, 824-830 (2002) 

  37. Young, A. J., Wellings R., and Britton G., The fate of chloroplast pigments during senescence of primary leaves of Hordeum vulgare and Avena sativum. J. Plant Physiol., 137, 701-705 (1991) 

  38. Zhang, H., Joseph, J., Felix, C., and Kalyanaraman, B., Bicarbonate enhances the hydroxylation, nitration, and peroxidation reactions catalyzed by copper, zinc superoxide dismutase : intermediacy of carbomate anion radical. J. Biol. Chem., 275, 14038-14045 (2000) 

저자의 다른 논문 :

관련 콘텐츠

오픈액세스(OA) 유형

FREE

Free Access. 출판사/학술단체 등이 허락한 무료 공개 사이트를 통해 자유로운 이용이 가능한 논문

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로