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9종의 허브류로부터 ACE 저해활성, HMG-CoA reductase 저해활성 및 혈전용해활성에 대한 검색

Screening of Nine Herbs with Biological Activities on ACE Inhibition, HMG-CoA Reductase Inhibition, and Fibrinolysis

한국식품과학회지 = Korean journal of food science and technology, v.38 no.5 = no.189, 2006년, pp.691 - 698  

권은경 (한국식품연구원) ,  김영언 (한국식품연구원) ,  이창호 (한국식품연구원) ,  김해영 (경희대학교 식품생명공학과)

초록
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본 연구는 혈액순환 개선 효능을 알아보기 위해 민간에서 빈번하게 사용하는 허브류인 마조람, 라벤더, 딜, 로즈마리, 히솝, 장미, 레몬밤, 파인애플 세이지 및 에키네시아 등 총 9종 을 실험 시료로 선정하였다. 이들을 부위별 및 용매별로 추출하여 angiotensin I converting enzyme(ACE) 저해 활성, hydroxy-methylglutalyl coenzyme A reductase 저해활성 및 혈전용해활성을 측정하였다. 추출 수율은 장미꽃이 가장 높았으며 열수 추출의 경우 43.3%였고 70% 에탄올 추출의 경우 45%였다. ACE 저해활성은 열수 추출의 경우 장미꽃이 133.8% 로 가장 높았고 70% 에탄올 추출의 경우에는 파인애플 세이지 잎이 91.2%로 가장 높았다. HMG-CoA reductase 저해활성의 경우에는 장미꽃이 열수 추출물 48.9%, 70% 에탄올 추출물 80.5%로 모두 높았다. 혈전용해활성도 장미꽃에서 열수 추출이나 에탄올 추출물 모두 가장 높은 활성을 보였다. 이상의 결과로 볼 때 장미꽃 추출물의 혈액순환 개선 효과가 뛰어난 것으로 나타나 기능성 식품으로의 개발 가능성이 기대된다.

Abstract AI-Helper 아이콘AI-Helper

The purpose of this study was to investigate how herb extracts may improve blood circulation. Twenty-six extracts from nine different herbs (marjoram, lavender, dill, rosemary, hyssop, rose, lemon balm, pineapple sage, and echinacea) were evaluated for their anti-hypertensive effects via angiotensin...

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가설 설정

  • Sample solution was 10 mg/mL. The abbreviation of each sample see the Table 2 or 3. Bars represent means ± SD. Bars without a common letter differ significantly at p < 0.
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