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체중 부하 운동이 흰쥐의 골대사에 미치는 영향

The Effects of Erect Bipedal Stance Exercise on Bone Formation and Resorption in Rats

Abstract

The effects of the erect bipedal stance exercise on bone mass and the biomarkers of bone formation and resorption were investigated in rats. Five-week old rats were assigned into control and exercise groups. The rats of exercise group were weight-bearing-trained for 13 weeks in the cage designed to adjust progressively the height from 26.5 cm to 31.5 cm to force the rats rising an erect bipedal stance for feeding and drinking. There was no significant difference in food intakes between two groups. But body weight gain was significantly increased in control group. The lengths of femur, tibia, humerus and radius were significantly longer in control group than exercise group, but the femur and tibia weights per body weight were significantly higher in exercise group than control group. Also the breaking force of femur and tibia in exercise group were higher than control group significantly. The calcium contents of femur and tibia were significantly increased in exercise group than control group. The activity of bone specific alkaline phosphatase (B-ALP) and the osteocalcin contents of serum (the biomarkers of bone formation) in exercise group were higher than control group, but the carboxyterminal propeptide of type I procollagen (P1CP) contents of serum did not show any difference between two groups. However the urinary deoxypridinolin (DPD) excretion, biomarker of bone resorption, was significantly lower in exercise group than control group. From these results, it has been indicated that the erect bipedal stance exercise enhanced the density and the strength of femur and tibia by increasing biomarkers of bone formation and suppressing a biomarker of bone resorption in rats.

참고문헌 (22)

  1. Inoue K, Ohguchi H, Yoshikawa T, Okumura M, Sempuku T, Tamai S, Dohi Y. The effect of aging on bone formation in porous hydroxyapatite: biochemical and histological analysis. J Bone Miner Res 12: 989-994, 1997 
  2. Petra JM, Lips P. Long term effect of calcium supplementationreduces in perimenopausal women. J Bone Miner Res(suppl): 963-970, 1994 
  3. Sandler RB, Slemenda C, Laporte RE. Postmenopausal bonedensityand milk consumption in children and aldolesence. Am J Clin Nutr 42: 270-274 1985 
  4. Karlsson M, Johnell O, Obrant K. Bone mineral density in weight lifter. Calicif Tissue Int 52: 212-215, 1993 
  5. Forst HM. Erect bipedal stance exercise partially prevents orchidectomy- induced bone loss in the lumbar vertebrae of rats. Bone 27(5): 667-675, 2000 
  6. Hong H, Lee JH, Chung DC, So JM, Ryoichi N, Choi EC, Hwang GH, Ahn EH, Maeng WJ. Influence of various types of exercise on bone formation and resorption in rats. Korean J Nutrition 34(4): 541-546, 2001 
  7. Fujimura R, Ashizawa N, Watanabe M, Mukai N, Amagai H, Fukubayashi T, Hayashi K, Tokuyama K, Suzuki M. Effect of resistance exercise training on bone formation and resorption in young male subjects assessed by biomarkers of bone metabolism. J Bone Miner Res 12(4): 656-662, 1997 
  8. Chambers TJ, Evans M, Gardner TN, Turner SA. Chow JW. Induction of bone formation in rat trail vertebrae by mechanical loading. Bone Miner 20: 167-178, 1993 
  9. Hillam RA, Skerry TM. Inhibition of bone resorption and stimulation of formation by mechanical loading of the modeling rat ulna in vivo. J Bone Miner Res 10: 683-689, 1995 
  10. Vergaehge J, Thomsen TS, Bree R, Herck E, Mosekilde LI. Effects of exercise and disuse on bone remodeling, bone mass, and biomechanical competence in spontaneously diabetic female rats. Bone 27(2): 249-256, 2000 
  11. Hannson T, Ross B. Age change in the bone mineral density of lumbar spine in normal women. Calcif Tissue Int 38: 328-332, 1984 
  12. Darby LA, Pohlman RL, Lechner AJ. Increased bone calcium following endurance exercise in the mature female rat. Laboratory Animal Science 35(4): 382-386, 1985 
  13. Yoo HJ. Nutritional problems in the elderly patients. Korean J Nutrition 27(6): 666-674, 1994 
  14. Ducy P, Amling M, Takeda S, Priemel M. Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass. Cell 100: 197-207, 2000 
  15. Jennifer EL, Miriam EN. The effects of progressive resistance training on bone density: a review. Med Sci Sports Exerc 31(1): 25-30, 1999 
  16. Aloia JF, Cohn SH, Ostuni JA, Ellis K. Prevention of evaluational bone loss by exercise. Annals of Internal Medicine 89: 356-358, 1978 
  17. Westerland KC, Fluckey JD, Gordon SE, Kraemer WJ, Farrell PA, Turner RT. Effect of resistance exercise training on cortical and cancellous bone in mature male rats. J Appl Physio, pp. 459-464, 1998 
  18. Liang CT, Barnes J, Seedor JG, Quartuccio HA, Bolander M, Jeffrey JJ, Rodam GA. Impaired bone activity in aged rats: alterations at the cellular and molecular levels. Bone 13: 435-441, 1992 
  19. Consensus Development Conference: Diagnosis, prophylaxis and treatment of osteoporosis: a review. Am J Med Jun 94(6): 646- 650, 1993 
  20. Layne JE, Nelson ME. The effects of progressive resistance training on bone density: a review. Med Sci Sports Exerc 31(1): 25- 30, 1999 
  21. Lee HJ, Kim MJ. The effect of nutrient intake and energy expenditure on bone mineral density of Korean women in Taegu. Korean J Nutrition 29(6): 622-633, 1996 
  22. Wolman R, Faulmann L, Clark P, Hesp R, Harries M. Different training patterns and bone mineral density of the femoral shaft in elite female athletes. Annals of Rheumatic Diseases 50: 487-489, 1991 

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