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산모와 영아의 혈청 렙틴 농도와 체중, 체질량지수, 체지방율과의 상관관계에 관한 연구

A Study on Relationship of Serum Leptin Levels with Body Weight, Body Mass Index, and Percent Body Fat in the Mothers and Their Infants

Abstract

To estimate whether serum leptin has any effects on body composition during the lactational and postnatal periods, we investigated the relationship of serum leptin levels and anthropometric parameters at right after delivery and 16 weeks after delivery in mothers and their infants. Subjects who signed the concent form, participated in this study were recruited from K university hospital. Characteristics of the subjects (age; $31.0{\pm}4.2$ yr, gestation period; $39.5{\pm}1.0$ wk) were investigated and anthropometric parameters (weight, height, body mass index and percent body fat for mothers, and weight, height, head circumference, chest circumference, and Kaup index for infants) were measured. Serum leptin levels of mothers and their infants also measured. Mean maternal serum leptin levels were $9.9{\pm}8.2ng/ml$ and $9.1{\pm}7.2ng/ml$ at right after delivery and 16 weeks after delivery, respectively showing no significant differences. Mean infant's serum leptin levels at birth $(1.8{\pm}0.4ng/ml)$ were significantly lower than that of at 16 weeks after birth $(4.2{\pm}0.8ng/ml)$ (p < 0.001). Leptin levels of male infants were not different from those of female infants. There were no correlations between the maternal serum leptin levels with their body weight, percent body fat after delivery. However, significant correlations were found between maternal serum leptin levels with their body weight, BMI, percent body fat at 16 weeks after delivery (r = 0.80, p < 0.01, r = 0.90, p < 0.001; r = 0.83, p < 0.01, respectively). There were no correlations between the infant's serum leptin levels and their weight, height, head circumference, and chest circumference. No significant relations were also found between maternal serum leptin levels with those of their infants. As a conclusion, maternal serum levels of leptin should be used with a caution to estimate their infant's leptin levels as well as their anthropometric parameters. Further researches are needed to examine the relationship among the leptin levels of mother's serum, breast milk, placenta, and infant's serum.

참고문헌 (39)

  1. Oumachigui A. Prepregnancy and pregnancy nutrition and its impact on women's health. Nutr Rev 60(5): 64s-67s, 2002 
  2. Kratzsch J, Schubring C, Stitzel B, Bottner A, Berthold A, Thiery J, Kiess W. Inverse changes in the serum levels of the soluble leptin receptor and leptin in neonates: relations to anthropometric data. J Clin Endocrinol Metab 90(4): 212-2217, 2005 
  3. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 372(6505): 425-432, 1994 
  4. Linnemann K, Malek A, Schneider H, Fusch C. Physiological and pathological regulation of feto/placenta/maternal leptin expression. Biochem Soc 29(2): 86-90, 2001 
  5. Masuzaki H, Ogawa Y, Sagawa N, Hosoda K, Matsumoto T, Mise H, Nishmura H, Yoshimasa Y, Tanaka I, Mori T, Nakao K. Nonadipose tissue production of leptin: leptin as a novel placentaderived hormone in humans. Nat Med 3(9): 1029-1033, 1997 
  6. Holness MJ, Munns MJ, Sugden MC. Current concepts concerning the role of leptin in reproductive function. Mol Cell Endocrinol 157(1-2): 11-20, 1999 
  7. Mounzih K, Qiu J, Ewart-Toland A, Chehab FF. Leptin is not necessary for gestation and parturition but regulates maternal nutrition via a leptin resistance state. Endocrinology 139(12): 5259-5262, 1998 
  8. Tamas P, Sulyok E, Szabo I, Vizer M, Ertl T, Rascher W, Blum WF. Changes of maternal serum leptin levels during pregnancy. Gynecol Obstet Invest 46(3): 169-171, 1998 
  9. Lage M, Garcia-Mayor RV, Tome MA, Cordido F, Valle-Inclan F, Considine RV, Caro JF, Dieguez C, Casanueva FF. Serum leptin levels in women throughout pregnancy and the postpartum period and in women suffering spontaneous abortion. Clin Endocrinol (Oxf) 50(2): 211-216, 1999 
  10. Geary M, Pringle PJ, Persaud M, Wilshin J, Hindmarsh PC, Rodeck CH, Brook CG. Leptin concentrations in maternal serum and cord blood: relationship to maternal anthropometry and fetal growth. Br J Obstet Gynecol 106(10): 1054-1060, 1999 
  11. Highman TJ, Friedman JE, Huston LP, Wong WW, Catalano PM. Longitudinal changes in maternal serum leptin concentrations, body composition, and resting metabolic rate in pregnancy. Am J Obstet Gynecol 178(5): 1010-1015, 1998 
  12. Yang MJ. Interrelationships of maternal serum leptin, body mass index and gestational age. J Chin Med Assoc 68(10): 452-457, 2005 
  13. Butte NF, Hopkinson JM, Nicolson MA. Leptin in human reproduction: serum leptin levels in pregnant and lactating women. J Clin Endocrinol Metab 82(2): 585-589, 1997 
  14. Stein TP, Scholl TO, Schluter MD, Schroeder CM. Plasma leptin influences gestational weight gain and postpartum weight retention. Am J Clin Nutr 68(6): 1236-1240, 1998 
  15. Kirel B, Tekin N, Tekin B, Kilic FS, Dogruel N, Aydogdu SD. Cord blood leptin levels: relationship to body weight, body mass index, sex and insulin and cortisol levels of maternal-newborn pairs at delivery. J Pediatr Endocrinol Metab 13(1): 71-77, 2000 
  16. Schubring C, Kiess W, Englaro P, Rascher W, Dotsch J, Hanitsch S, Attanasio A, Blum WF. Levels of leptin in maternal serum, amniotic fluid, and arterial and venous cord blood: relation to neonatal and placental weight. J Clin Endocrinol Metab 82(5): 1480-1483, 1997 
  17. Matsuda J, Yokota I, Iida M, Murakami T, Naito E, Ito M, Shima K, Kuroda Y. Serum leptin concentrations in cord blood: relationship to birth weight and gender. J Clin Endocrinol Metab 82: 1642-1644, 1997 
  18. Cetin I, Morpurgo PS, Radaelli T, Taricco E, Cortelazzi D, Bellotti M, Pardi G, Beck-Peccoz P. Fetal plasma leptin concentrations: relationship with different intrauterine growth patterns from 19 weeks to term. Pediatr Res 48(5): 646-651, 2000 
  19. Harigaya A, Onigata K, Nako Y, Nagashima K, Morikawa A. Role of serum leptin in the regulation of weight gain in early infancy. Biol Neonate 75(4): 234-238, 1999 
  20. Lee YY, Park GS, Park DJ, Park KS, Kim SY, Cho BY, Lee HK, Jun JK, Yoon BH. Serum leptin in cord blood and its relation with birth weight and metabolic parameters. J Kor Soc Endocrinol 14(2): 365-371, 1999 
  21. Lee HJ, Kim GH, Rhu SW, Park DC, Kim JH, Kwon DJ, Kim SJ, Lew YO, Kim DH. A study on the leptin concentrations in maternal and cord blood. Kor J Obstet Gynecol 47(1): 5-9, 2004 
  22. Park JH, Kim SB, Cho KH, Choue RW. Maternal nutritional status at the end of pregnancy, and correlation among pregnancy weight gain, birth weight and serum leptin levels. Korean J Nutrition 39(5): 467-475, 2006 
  23. Korean pediatric growth standards. The Korean Pediatrics Society, Seoul, 1998 
  24. WHO western pacific region. The asia-pacific perspective: redefining obesity and its treatment, 2000 
  25. Lee JW, Lee MS, Kim JH, Son SM, Lee BS. Nutrition assessment. Kyomunsa, Seoul, pp.109-110, 2001 
  26. Tamura T, Goldenberg RL, Johnston KE, Cliver SP. Serum leptin concentrations during pregnancy and their relationship to fetal growth. Obstet Gynecol 91(3): 389-395, 1998 
  27. Schubring C, Englaro P, Siebler T, Blum WF, Demirakca T, Kratzsch J, Kiess W. Longitudinal analysis of maternal serum leptin levels during pregnancy, at birth and up to six weeks after birth: relation to body mass index, skinfolds, sex steroids and umbilical cord blood leptin levels. Horm Res 50(5): 276-283, 1998 
  28. Matsuda J, Yokota I, Iida M, Murakami T, Yamada M, Saijo T, Naito E, Ito M, Shima K, Kuroda Y. Dynamic changes in serum leptin concentrations during the fetal and neonatal periods. Pediatric Res 45(1): 71-75, 1999 
  29. Andrew C, Sophie M, Maria O, Charles C, Andrew P. Developmental changes in leptin as a measure of energy status in human infants in a natural ecologic setting. Am J Clin Nutr 81(2): 488- 494, 2005 
  30. Ong KKL, Ahmed ML, Sherriff A, Woods KA, Watts A, Golding J, Dunger DB. Cord blood leptin is associated with size at birth and predicts infancy weight gain in humans. J Clin Endocrinol Metab 84(3): 1145-1148, 1999 
  31. Hytinanntt T, Koistinen HA, Koivisto VA, Karonen SK, Andersson S. Changes in leptin concentration during the early postnatal period: adjustment to extrauterine life? Pediatr Res 45(2): 197- 201, 1999 
  32. Akcurin S, Velipasaoglu S, Akcurin G, Guntekin M. Leptin profile in neonatal gonadotropin surge and relationship between leptin and body mass index in early infancy. J Pediatr Endocrinol Metab 18(2): 189-195, 2005 
  33. Roemmich JN, Rogol AD. Role of leptin during childhood growth and development. Endocrinol Metab Clin North Am 28(4): 749-764, 1999 
  34. Considine RV, Sinha MK, Heiman ML, Kriauciunas A, Stephens TW, Nyce MR, Ohannesian JP, Marco CL, McKee LJ, Bauer TL. Serum immunoreactive leptin concentrations in normal weight and obese humans. N Engl J Med 334(5): 292-295, 1996 
  35. Bellone S, Rapa A, Petri A, Zavallone A, Strigini L, Chiorboli E, Ciardi L, Aguzzi A, Bona G. Leptin levels as function of age, gender, auxological and hormonal parameters in 202 healthy neonates at birth and during the first month of life. J Endocrinol Invest 27(1): 18-23, 2004 
  36. Laml T, Hartmann BW, Ruecklinger E, Preyer O, Soeregi G, Wagenbichler P. Maternal serum leptin concentrations do not correlate with cord blood leptin concentrations in normal pregnancy. J Soc Gynecol Invest 8(1): 43-47, 2001 
  37. Schubring C, Siebler T, Kratzsch J, Englaro P, Blum WF, Triep K, Kiess W. Leptin serum concentrations in healthy neonates within the first week of life: relation to insulin and growth hormone levels, skinfold thickness, body mass index and weight. Clin Endocrinol(Oxf) 51(2): 199-204, 1999 
  38. Martinez-Cordero C, Amador-Licona N, Guizar-Mendoza JM, Hernandez-Mendez J, Ruelas-Orozco, G. Body fat at birth and cord blood levels of insulin, adiponectin, leptin, and insulin-like growth factor-I in small-for-gestational-age infants. Arch Med Res 37(4): 490-494, 2006 
  39. Sarandakou A, Protonotariou E, Rizos D, Malamitsi-Puchner A, Giannaki G, Phocas I, Creatsas G. Serum leptin concentrations during the perinatal period. Am J Perinatol 17(6): 325-328, 2000 

이 논문을 인용한 문헌 (1)

  1. Oh, Hyun-Hee ; Shin, Eun-Jung ; Kim, Hyun-Sook ; Lim, Yun-Sook ; Park, Mi-Young ; Kim, Kkoch-Byul ; Kim, Eun-Mee ; Lee, Myoung-Sook 2007. "Apo E4 Genotype as the Alzheimer Indictor in Korean Senior Subjects Aged 50 to 64 Years Old" 韓國營養學會誌 = The Korean journal of nutrition., 40(7): 593~600 

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