Nelumbo nucifera root(NNR) is used to clear summerheat(暑熱), bear Yang(陽) upwards and stop bleeding as mentioned in traditional Korean medicine. Also, it has been known that NNR is effective for lowering blood pressure and hyperlipidemia. The rhizome is considered to be nutritive, demulcent, diuretic...
Nelumbo nucifera root(NNR) is used to clear summerheat(暑熱), bear Yang(陽) upwards and stop bleeding as mentioned in traditional Korean medicine. Also, it has been known that NNR is effective for lowering blood pressure and hyperlipidemia. The rhizome is considered to be nutritive, demulcent, diuretic and cholagogue and is used to treat piles, dyspepsia and diarrhea. An increasingly growing market for nutraceuticals and functional foods has triggered the study on natural sources for nutraceuticals, health foods and functional foods. But rhizome was inconvenient to formulate liquid dosage form(extract) by way of hot water because of its limited storage. Also the majority of the consumers have a complaint against the dosage. The purpose of this study was to develop the functional materials from NNR without side effects. We formulated the solid dosage form viz tablet and granule from the lotus root. Sensory evaluation was performed in terms of smell, taste, color and overall of lotus root and all colored forms(brown, dark brown, light green and yellow) of tablet and granule to evaluate the acceptability of the formulated tablets and granules. In sensory evaluation, among the formulated tablets and granules, light green granules obtained best score overall and yellow tablets showed the overall improved acceptability. In conclusion, lotus rhizome could be recommended as functional food. Further studies to clarify bioactive functions of Nelumbo nucifera in experimental animal model on atopic dermatitis are in progress.
Nelumbo nucifera root(NNR) is used to clear summerheat(暑熱), bear Yang(陽) upwards and stop bleeding as mentioned in traditional Korean medicine. Also, it has been known that NNR is effective for lowering blood pressure and hyperlipidemia. The rhizome is considered to be nutritive, demulcent, diuretic and cholagogue and is used to treat piles, dyspepsia and diarrhea. An increasingly growing market for nutraceuticals and functional foods has triggered the study on natural sources for nutraceuticals, health foods and functional foods. But rhizome was inconvenient to formulate liquid dosage form(extract) by way of hot water because of its limited storage. Also the majority of the consumers have a complaint against the dosage. The purpose of this study was to develop the functional materials from NNR without side effects. We formulated the solid dosage form viz tablet and granule from the lotus root. Sensory evaluation was performed in terms of smell, taste, color and overall of lotus root and all colored forms(brown, dark brown, light green and yellow) of tablet and granule to evaluate the acceptability of the formulated tablets and granules. In sensory evaluation, among the formulated tablets and granules, light green granules obtained best score overall and yellow tablets showed the overall improved acceptability. In conclusion, lotus rhizome could be recommended as functional food. Further studies to clarify bioactive functions of Nelumbo nucifera in experimental animal model on atopic dermatitis are in progress.
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문제 정의
Based on this information, we formulated solid dosage form using lotus root as raw material. The purpose of this study was to develop the functional materials from natural resource without side effects.
제안 방법
Condition and state, disintegration, loss on diying and size were the parameters used to evaluate the stability of granule under the room temperature and accelerated condition (4013 and relative humidity of 75%). Similarly, condition and state, hardness, disintegration and mean weight were used to evaluate the stability of tablet under the room temperature and accelerated condition (40 "0 and relative humidity of 75%).
The graphical representation of sensory evaluation of formulated solid dosage forms granules and tablets against lotus root as raw material are shown in figures 2 and 3 respectively.Sensory evaluation was performed in terns of color, smell, taste and overall of lotus root and solid dosage forms granules and tablets. The color of light green and yellow granules were more accepted and scored 7.
대상 데이터
A sensorial evaluation performed by 58 non trained volunteers (age between 20 to 60 years) evaluated color, smell, taste and overall of different color samples. A nine-point hedonic scale was used for the analysis.
이론/모형
of different color samples. A nine-point hedonic scale was used for the analysis.
참고문헌 (9)
Kirtikar K. R. and B. D. Basu. 1975. 116-120p, Indian medicinal plants, Deharadun, India.
Mukherjee P. K., K. Saha, R. Balasubramanian, M. Pal. and B. P. Saha. 1996. Studies on psychopharmacological effects of Nelumbo nucifera Gaertn. rhizome extract. Journal of ethnopharmacology 54: 63-67
Cevallos-Casals B. A. and L. Cisneros-Zevallos. 2003. Stoichiometric and Kinetic Studies of Antioxidants from Andean Purple Corn and Red-Fleshed Sweetpotato. Journal of Agricultural and Food Chemistry 51: 3313-3319
Mukherjee P. K., K. Saha, M. Pal. and B. P. Saha. 1997. Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats. Journal of Ethnopharmacology 58: 207-213
Mukherjee P. K., J. Das, K. Saha, S. N. Giri, M. Pal and B. P. Saha. 1996. Antipyretic activity of Nelumbo nucifera rhizome extract. Indian J. Exp. Biol. 34(3): 275-6
Kim D. W., S. B. Kim. and S. D. Kim. 2005. Inhibitory effect of lotus rhizome on matrix metalloproteinase-2 and 9. Journal of Traditional medicines 22: 162
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