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논문 상세정보


This study was performed to improve antioxidant activities and skin-whitening effects of Rubus coreanus Miquel extracts by nano-encapsulation. R. coreanus was extracted at $60^{\circ}C$ and encapsulated by lecithin and gelagine. Nano-encapsulated extracts showed highest free radical scavengering effect as 97.62% in adding sample ($500\;{\mu}g/m{\ell}$), compared to the extracts from conventional processes. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 55.23%. High inhibitory potency on tyrosinase was also measured as 155.8% by adding nano-sample of 1 $mg/m{\ell}$. The improvement of biological activity was demonstrated by real time confocal microscope. We could consider that the water soluble extracts of R. coreanus could be definitely enhanced by nano-encapsulated as a potent natural resources for antioxidant and skin-whitening agent.

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이 논문을 인용한 문헌 (15)

  1. Ha, Sang-Keun ; Moon, Eun-Jung ; Lee, Min-Jae ; Park, Hye-Min ; Yoo, Eun-Sook ; Oh, Myung-Sook ; Kim, Sun-Yeou 2009. "Effect of the BuOH Soluble Fraction of Cinnamomum camphora on Melanin Biosynthesis" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 17(4): 293~300 
  2. Seo, Yong-Chang ; Choi, Woon-Yong ; Kim, Ji-Seon ; Zou, Yun-Yun ; Lee, Choon-Geun ; Ahn, Ju-Hee ; Shin, Il-Shik ; Lee, Hyeon-Yong 2010. "Enhancement of Antimicrobial Activity of Nano-Encapsulated Horseradish Aqueous Extracts Against Food-Borne Pathogens" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 18(6): 389~397 
  3. Jeong, Hyang-Suk ; Kim, Seoung-Seop ; Oh, Sung-Ho ; Jeong, Myoung-Hoon ; Choi, Woon-Yong ; Seo, Yong-Chang ; Na, Chun-Soo ; Kwak, Hyeong-Geun ; Lee, Hyeon-Yong 2010. "Enhancement of Anticancer Activities of Ephedra sinica Stapf Extracts by Nano-encapsulation" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 18(3): 143~150 
  4. Kim, Myeong-Ok ; Kim, Ju-Sung ; Sa, Yeo-Jin ; Jeong, Hyun-Ju ; Chun, Wan-Joo ; Kwon, Yong-Soo ; Kim, Tae-Young ; Choi, Han-Seok ; Yu, Chang-Yeon ; Kim, Myong-Jo 2010. "Screening of Extraction Solvent Condition of Fermented Rhus verniciflua Stem Bark by Antioxidant Activities" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 18(4): 217~223 
  5. Kwon, Ji-Wung ; Lee, Hee-Kwon ; Park, Hee-Jeon ; Kwon, Tae-Oh ; Choi, Heh-Ran ; Song, Ji-Young 2011. "Screening of Biological Activities to Different Ethanol Extracts of Rubus coreanus Miq." 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 19(5): 325~333 
  6. Lee, Kyoung-In ; Kim, Su-Min ; Kim, Sun-Min ; Pyo, Byoung-Sik 2011. "Comparison of Fatty Acids and Antibacterial Activity against Pathogen of Acne in Different Parts of Ripened Black Raspberry (Rubus coreanus Miquel)" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 40(3): 466~469 
  7. Cha, Bae-Cheon 2011. "Tyrosinase, Hyaluronidase Inhibitory Effect and Antioxidant Activity of Medicinal Plants" 생약학회지, 42(1): 89~97 
  8. Kim, Geum-Soog ; Park, Chun-Geun ; Lee, Kyeong-Hee ; Choi, Jehun ; Lee, Seung-Eun ; Noh, Hyung-Jun ; Lee, Jeong-Hoon ; Kim, Seung-Yu 2011. "Investigation of Shikonin Pigments and Antioxidant activity of the Roots from Lithospermum erythrorhizon according to the Different Growth Stages and Areas of Cultivation" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 19(6): 435~440 
  9. Gwak, Mi-Kyung ; Choi, Hee-Sun ; Manochai, Benya ; Hong, Jeong-Hwa 2011. "Extraction Procedures for Free Radical Scavenging Activity from Noni Fruit (Morinda citrifolia)" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 19(1): 38~46 
  10. Cho, Eun-Ah ; Cho, Eun-Hye ; Choi, Sun-Ju ; Park, Keun-Hyoung ; Kim, So-Young ; Jeong, Yoon-Joo ; Ku, Chang-Sub ; Ha, Byung-Jhip ; Jang, Dong-Il ; Chae, Hee-Jeong 2011. "Screening of Anti-wrinkle Resource from Herbal Medicinal Extracts and Stability Test of Its Cosmetic Products" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 19(2): 126~135 
  11. Kwon, Ji-Wung ; Lee, Hee-Kwon ; Park, Hee-Jeon ; Song, Ji-Young 2012. "Physiological Activities of Rubus coreanus Miq. Extracts Using Different Extraction Methods" 한국식품조리과학회지 = Korean Journal of Food & Cookery Science, 28(1): 25~32 
  12. Lee, Jai-Sung ; Choi, Hee-Young ; Bae, Inhyu 2013. "Quality Properties of Yoghurt Added with Bokbunja (Rubus coreanus Miquel) Wine" Korean journal for food science of animal resources = 한국축산식품학회지, 33(6): 806~816 
  13. Jun, Hyun-Il ; Kim, Young-Ae ; Kim, Young-Soo 2014. "Antioxidant Activities of Rubus coreanus Miquel and Morus alba L. Fruits" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 43(3): 381~388 
  14. Chae, Kyu Seo ; Jung, Ji Hye ; Yoon, Hae Hoon ; Son, Rak Ho 2014. "Antioxidant Activity and Main Volatile Flavor Components of Mulberry Wine Fermented with Saccharomyces cerevisiae B-8" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 43(7): 1017~1024 
  15. Seo, Eun Young ; Kim, Myung Hwan ; Kim, Woo-Kyoung ; Chang, Moon-Jeong 2015. "Comparing the anti-inflammatory effect of nanoencapsulated lycopene and lycopene on RAW 264.7 macrophage cell line" Journal of nutrition and health, 48(6): 459~467 

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