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Phaleria macrocarpa Suppress Nephropathy by Increasing Renal Antioxidant Enzyme Activity in Alloxan-Induced Diabetic Rats

Natural product sciences, v.15 no.3, 2009년, pp.167 - 172  

Triastuti, Asih (Department of Pharmacy, UII University) ,  Park, Hee-Juhn (Department of Industrial Pharmacy, Sangji University) ,  Choi, Jong-Won (College of Pharmacy, Kyungsung University)

Abstract AI-Helper 아이콘AI-Helper

The protective effects of Phaleria macrocarpa (PM) against oxidative stress in diabetic rats were investigated. Diabetes was induced in male Sprague Dawley rats using alloxan (150 mg/kg i.p). After the administration of PM fractions for two weeks the diabetic symptoms, nephropathy and renal antioxid...

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  • Significant differences between the mean values were statistically analyzed using one-way analysis of variance, and further analyzed using Duncan’s multiple range tests.
  • Statistical Analysis – All statistical analyses were carried out using the SPSS version 12 statistical program (SPSS Inc. Chicago, IL, USA), with data represented as the mean ± SD (n = 6).
  • Values within a column with different superscripts are significantly different at from the Duncan’s multiple range test (P < 0.05).
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