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논문 상세정보

맥문동(Liriope platyphylla) 잎과 뿌리 추출물의 생리활성

Physiological Activities of Leaf and Root Extracts from Liriope platyphylla

초록

국내에서 한약 재료로 생산, 유통, 사용되고 있는 맥문동(L. platyphylla) 잎과 뿌리 추출물의 생리활성 물질 탐색을 위한 연구로 폴리페놀과 플라보노이드 화합물 함량, 전자공여능 및 xanthine oxidase 저해활성 등 생리활성 효과를 측정하였다. 물과 메탄올을 용매로 추출한 맥문동 잎과 뿌리 추출물에 대한 수율을 측정한 결과 뿌리 물 추출물이 53.96%로 가장 높은 수율을 나타내었으며, 잎의 물 추출물은 27.5%으로 나타났다. 폴리페놀 화합물 함량은 잎의 메탄올 추출물에서 186.88 mg/g를 함유하며 플라보노이드는 잎의 물 추출물에서 159.29 mg/g을 함유하였다. 맥문동 잎의 메탄올 추출물은 0.5 mg/mL의 농도에서 97.42%의 전자공여능을 나타내었다. 잎의 물 추출물에서 9.75%의 SOD 유사활성능을 나타내었으며, pH 1.2 조건에서 잎의 메탄올 추출물은 40.52%의 아질산염 소거율을 보였으나 뿌리 추출물은 농도와 pH에 관계없이 아질산염 소거능이 없었다. Xanthine oxidase 저해율은 1.0 mg/mL의 농도에서 잎 추출물 모두 99% 이상의 저해 활성을 나타내었으며, 뿌리는 물 추출물 93.75%, 메탄올 추출물 68.47%로 뿌리보다 잎 추출물의 xanthine oxidase 저해효과가 높았다. Tyrosinase 저해 활성을 측정한 결과에서는 맥문동 잎의 물 추출물에서 22.80%의 저해효과가 나타났으나 메탄올 추출물과 뿌리 추출물은 저해효과가 없었다. 이상의 결과 추출물에 대한 수율은 맥문동 잎보다 뿌리가 더 높았으나 폴리페놀과 플라보노이드 함량, 전자공여능, SOD 유사활성, 아질산염 소거 및 xanthine oxidase와 tyrosinase에 대한 저해 활성이 한방생약재로 사용되는 맥문동 뿌리보다 비약용부위인 잎 추출물이 더 우수한 것으로 분석되었다.

Abstract

We compared physiological activities in reflux extracts from Liriope platyphylla leaves and roots. The water extract of roots had the highest solid extraction yield of 53.96%. The greatest level of total polyphenols was 186.88 mg/g in methanol extracts from leaves, whereas water extract from leaves showed the highest concentration of flavonoid compounds, at 159.29 mg/g. The leaf extract had 97.42% of the electron-donating ability (EDA) of the positive control, at 0.5 mg/mL. The superoxide dismutase (SOD)-like activity of water extract of leaves was 9.75% of the positive control value, at 1.0 mg/mL. The nitrite scavenging ability of methanolic extract from leaves was highest, at 40.56% of the positive control level at pH 1.2 and a concentration of 1.0 mg/mL, whereas root extracts were ineffective in this regard. Inhibition of xanthine oxidase by leaf extracts was more than 99% of the positive control value at 1.0 mg/mL, whereas water and methanolic root extracts had activities of 93.75% and 68.47%, respectively. When tyrosinase inhibition was examined, the water extract of leaves had 22.80% of positive control activity but methanolic extracts were inactive. These results indicate that leaves of L. platyphylla will be more useful for development of functional products than the roots, which are used to make medicinal preparations.

저자의 다른 논문

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이 논문을 인용한 문헌 (6)

  1. Song, Jung-Hwa ; Kang, Min-Gu ; Kim, Na-Mi ; Lee, Jong-Soo 2011. "Nutritional and Physiological Functionalities of Liriope Tuber (Cheongsim and Liriope Tuber No. 1)" 韓國藥用作物學會誌 = Korean journal of medicinal crop science, 19(6): 478~483 
  2. Lee, Hye-Jin ; Do, Jeong-Ryong ; Kwon, Joong-Ho ; Kim, Hyun-Ku 2011. "Physiological Properties of Oak Mistletoe (Loranthus yadoriki) Extracts by Microwave Extraction Condition" 한국식품저장유통학회지 = Korean journal of food preservation, 18(1): 72~78 
  3. Lee, Hye-Jin ; Do, Jeong-Ryong ; Kwon, Joong-Ho ; Kim, Hyun-Ku 2011. "Physiological Activities of Extracts from Different Parts of Cudrania tricuspidata" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 40(7): 942~948 
  4. Lee, Hye-Jin ; Do, Jeong-Ryong ; Kwon, Joong-Ho ; Kim, Hyun-Ku 2012. "Physiological Properties of $Corni$ $fructus$ Extracts Based on Their Extraction Condition" 한국식품저장유통학회지 = Korean journal of food preservation, 19(2): 271~277 
  5. Shin, Yu-Jin ; Hwang, Jeong-Man ; Lee, Seung-Cheol 2013. "Antioxidant and Xanthine Oxidase Inhibitory Activities of Hot Water Extracts of Medicinal Herbs" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 42(10): 1712~1716 
  6. Seo, Soo Jung ; Kim, Nam Woo 2014. "Antioxidant Activities of Extracts from Leaves and Stems of Achyranthes japonica" 한국식품영양과학회지 = Journal of the Korean Society of Food Science and Nutrition, 43(7): 972~979 

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