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Journal of plant biotechnology = 식물생명공학회지, v.37 no.3, 2010년, pp.243 - 249
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Molecular farming is production of pharmaceutically and industrially important proteins in plants. Plants and plant cell culture systems have been used as bio-factory to produce recombinant proteins such as monoclonal antibodies, enzymes, vaccines, hormones, interleukins, commercial enzymes and etc....
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| 핵심어 | 질문 | 논문에서 추출한 답변 |
|---|---|---|
| 분자농업이란? | 분자농업 (Molecular farming)이란 의약용 단백질, 산업용 단백질을 식물을 이용하여 생산하는 분야를 통틀어 말한다. 이 분야에 대한 관심을 반영하듯이 분자농업과 유사하게 쓰이는 용어는 biofarming, molecular pharming, phytomanufacturing, recombinant 또는 plant-made industrials, planta-pharma, plant bioreactors, plant biofactory, 그리고 pharmaceutical gardening 등 많은 용어들이 비슷한 의미로 혼용하여 사용하고 있다 (Basaran and Rodriguez-Cerezo 2008). | |
| 최초로 유전자 재조합기술에 의해 생산된 것은? | 1980년대에 유전자 재조합 기술이 발전하면서 미생물이나 효모를 이용하여 의약용 및 산업용 재조합단백질을 생산하려는 노력이 많이 이루어지기 시작하였다. 최초로 유전자 재조합기술에 의해서 생산된 것은 당뇨병의 치료제인 인간의 인슐린이다 (Walsh 1998). 초기에는 미생물과 효모를 이용하여 생산이 이루어지다가 동물세포, 형질전환 동물을 이용하여 많은 종류의 의약용과 산업용 단백질이 생산되고 있다. | |
| 유전자 재조합기술에 대한 생산은 어떻게 발전하고 있는가? | 최초로 유전자 재조합기술에 의해서 생산된 것은 당뇨병의 치료제인 인간의 인슐린이다 (Walsh 1998). 초기에는 미생물과 효모를 이용하여 생산이 이루어지다가 동물세포, 형질전환 동물을 이용하여 많은 종류의 의약용과 산업용 단백질이 생산되고 있다. 최근에는 식물의 형질전환 기술과 조직배양기술의 발전과 함께 형질전환 식물을 이용하여 의약용, 산업용 단백질을 생산하려는 노력이 이루어지고 있다. 형질전환 식물체를 이용하는 생산 체계는 식물을 이용함으로서 바이오매스를 얻기 위한 생산단가가 저렴하고, 대량생산을 위한 규모를 확대하는데 드는 비용이 저렴하다. |
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박기영 (2010) 농림수산식품 신성장 동력으로서 분자농업의 전망과 과제. 농림수산식품기술기획평가원.
http://www.ipet.re.kr/morgu/data_view.asp?seq13&page1&column&keyword&bo_tpcdL&func
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