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한국에서 분리된 소 바이러스성 설사 바이러스의 병리생물학적 분석

Pathobiological Analysis of Bovine Viral Diarrhea Virus Identified in the Republic of Korea

초록

계통발생 및 염기서열분석시 한우 송아지에서 중증의 급성 소 바이러스성 설사 바이러스 발생은 BVDV-2a에 속한 것으로 나타났고, BVDV-2 균주 890과는 독성 마커가 동일하였으며, 독성이 높은 것으로 분류되었다. 이들 BVDV 발생은 어린 송아지(20-40일령)에 주로 감염되었고, 임상증상으로 출혈성 설사, 침울, 식욕감퇴, 허약을 특징으로 하였다. 한우 송아지에서 고독성 BVDV-2의 발견은 역학조사, 진단 및 예방접종 전략에 중요한 영향을 내포한다.

Abstract

Phylogenetic and nucleotide analysis revealed that severe acute bovine viral diarrhea virus (BVDV) outbreaks from Korean indigenous calves belonged to BVDV-2a, and were identical to those of the highly pathogenic BVDV-2 strain 890, with identical virulence markers and classified as highly virulent. These outbreaks affected young calves (20 and 40 day-old) and were characterized by hemorrhagic diarrhea, depression, anorexia, and weakness. The identification of the highly virulent BVDV-2 isolates among Korean indigenous calves may have important implications for epidemiological studies, diagnostic and immunization strategies.

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참고문헌 (24)

  1. Baker JC. The clinical manifestations of bovine viral diarrhea infection. Vet Clin North Am Food Anim Pract 1995; 11: 425-445. 
  2. Carman S, van Dreumel T, Ridpath J, Hazlett M, Alves D, Dubovi E, Tremblay R, Bolin S, Godkin A, Anderson N. Severe acute bovine viral diarrhea in Ontario, 1993-1995. J Vet Diagn Invest 1998; 10: 27-35. 
  3. Choi KS, Song MC. Epidemiological observations of bovine viral diarrhea virus in Korean indigenous calves. Virus Genes 2011; 42: 64-70. 
  4. Corapi WV, French TW, Dubovi EJ. Severe thrombocytopenia in young calves experimentally infected with noncytopathic bovine viral diarrhea virus. J Virol 1989; 63: 3934-3943. 
  5. Couvreur B, Letellier C, Collard A, Quenon P, Dehan P, Hamers C, Pastoret PP, Kerkhofs P. Genetic and antigenic variability in bovine viral diarrhea virus (BVDV) isolates from Belgium. Virus Res 2002; 85: 17-28. 
  6. David GP, Crawshaw TR, Gunning RF, Hibberd RC, Lloyd GM, Marsh PR. Severe disease in adult dairy cattle in three UK dairy herds associated with BVD virus infection. Vet Rec 1994; 134: 468-472. 
  7. Donis RO. Moleular biology of bovine viral diarrhea virus and its interactions with the host. Vet Clin North Am Food Anim Pract 1998; 11: 393-423. 
  8. Drew TW, Sandvik T, Wakeley P, Jones T, Howard P. BVD virus genotype 2 detected in British cattle. Vet Rec 2002; 151: 551. 
  9. Flores EF, Gil LH, Botton SA, Weiblen R, Ridpath JF, Kreutz LC, Pilati C, Driemeyer D, Moojen V, Wendelstein AC. Clinical, pathological and antigenic aspects of bovine viral diarrhea virus (BVDV) type 2 isolates identified in Brazil. Vet Microbiol 2000; 77: 175-183. 
  10. Hibberd RC, Turkington A, Brownlie J. Fatal bovine viral diarrhoea virus infection of adult cattle. Vet Rec 1993; 132: 227. 
  11. Jones LR, Zandomeni R, Weber EL. Genetic typing of bovine viral diarrhea virus isolates from Argentina. Vet Microbiol 2001; 81: 367-375. 
  12. Nagai M, Sato M, Nagano H, Pang H, Kong X, Murakami T, Ozawa T, Akashi H. Nucleotide sequence homology to bovine viral diarrhea virus 2 (BVDV 2) in the 5' untranslated region of BVDVs from cattle with mucosal disease or persistent infection in Japan. Vet Microbiol 1998; 60: 271-276. 
  13. Odeon AC, Risatti G, Kaiser GG, Leunda MR, Odriozola E, Campero CM, Donis RO. Bovine viral diarrhea virus genomic associations in mucosal disease, enteritis and generalized dermatitis outbreaks in Argentina. Vet Microbiol 2003; 96: 133-144. 
  14. Oem JK, Hyun BH, Cha SH, Lee KK, kim SH, Kim HR, Park CK, Joo YS. Phylogenetic analysis and characterization of Korean bovine viral diarrhea viruses. Vet Microbiol 2009; 139: 356-360. 
  15. Pellerin C, van den Hurk J, Lecomte J, Tussen P. Identification of a new group of bovine viral diarrhea virus strains associated with severe outbreaks and high mortalities. Virology 1994; 203: 260-268. 
  16. Page RD. TreeView: an application to display phylogenetic trees on personal computers. Comput Appl Biosci 1996; 12: 357-358. 
  17. Ridpath JF, Bolin SR, Dubovi EJ. Segregation of bovine viral diarrhea virus into genotypes. Virology 1994; 205: 66-74. 
  18. Ridpath JF, Neill JD, Frey M, Landgraf JG. Phylogenetic, antigenic and clinical characterization of type 2 BVDV from North America. Vet Microbiol 2000; 77: 145-155. 
  19. Song MC, Choi KS. Phylogenetic analysis of bovine viral diarrhea virus from Korean indigenous calves in Gyeongbuk province. J Vet Clin 2010; 27: 635-639. 
  20. Tajima M, Frey HR, Yamato O, Maede Y, Moennig V, Scholz H, Greiser-Wilke I. Prevalence of genotypes 1 and 2 of bovine viral diarrhea virus in Lower Saxony, Germany. Virus Res 2001; 76: 31-42. 
  21. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res 1997; 25: 4876-4882. 
  22. Topliff CL, Kelling CL. Virulence markers in the 5' untranslated region of genotype 2 bovine viral diarrhea virus isolates. Virology 1998; 250: 164-172. 
  23. Vilcek S, Herring AJ, Herring JA, Nettleton PF, Lowings JP, Paton DJ. Pestiviruses isolated from pigs, cattle and sheep can be allocated into at least three genogroups using polymerase chain reaction and restriction endonuclease analysis. Arch Virol 1994; 136: 309-323. 
  24. Vilcek S, Greiser-Wilke I, Durkovic B, Obritzhauser W, Deutz A, Kofer J. Genetic diversity of recent bovine viral diarrhoea viruses from the southeast of Austria (Styria). Vet Microbiol 2003; 91: 285-291. 

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