Purpose: The purpose of this study was to identify the level of resilience, social support, depression, anxiety and self-efficacy in patients with colon cancer, and to examine factors affecting resilience. Methods: Data were collected from 121 patients who had been diagnosed with colon cancer, at the 'B' hospital in Gyeonggi province and 'J' hospital in Jeju from October 30th to November 20th in the year of 2012. The collected data were analyzed using descriptive statistics, t-test, one-way ANOVA, Scheffe's test, Pearson correlation coefficients and stepwise multiple regression in SPSS WIN 18.0 program. Results: The level of resilience significantly differed by occupation, average monthly household income, education level and existence of stoma. Resilience had significant positive correlation with family members support, friends supports, medical staff support and self-efficacy. Resilience had a significant negative correlation with anxiety and depression. Factors affecting resilience were education level, existence of stoma, friends supports, anxiety and depression with $R^2$ value of 65.9%. Conclusion: Measures to improve the resilience of colon cancer patients are needed as well as nursing intervention that includes social support such as medical staff support. Education level, existence of stoma, anxiety and depression should also be taken into account.
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