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식품과학과 산업 = Food science and industry, v.48 no.1, 2015년, pp.56 - 61
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| 핵심어 | 질문 | 논문에서 추출한 답변 |
|---|---|---|
| 위생가설을 뒷받침하는 보고들은 무엇입니까? | 경제 수준이 높아지고 사회가 선진화될수록 알레르기 질환의 유병률은 높아진다고 알려져 있으며, 이를 설명하는 것이 소위 “위생가설”이다. 즉, 감염성 질환의 발생률과 알레르기 질환의 유병률 간에는 역비례 관계가 있고(2) 가족 중 형제의 수가 많을수록 알레르기 질환의 발생이 감소한다는 보고들이 이러한 가설을 뒷받침하고 있다(3). 이 위생가설의 이론적 배경에는 Th1/Th2 면역상태의 균형이 위생 상태가 좋아짐에 따라 Th2 위주로 유지됨으로써 알레르기 질환이 발생한다는 면역학적 기전이 있다. | |
| 프로바이오틱스는 최근 어떠한 목적으로 사용되고 있습니까? | 프로바이오틱스는 인체 내에서 다양한 작용을 나타내는데, 최근에는 알레르기질환의 유병률이 높아짐에 따라 질환의 예방이나 치료의 목적으로 사용되고 있다. 그러나 그동안의 많은 연구에도 불구하고 프로바이오틱스의 알레르기질환에서의 효과는 많은 논란을 일으키고 있다. | |
| 프로바이오틱스란 무엇입니까? | 프로바이오틱스는 식품성분으로서 우리 몸에 유익한 효과를 보이는 살아있는 세균을 말한다(1). 일례로 Streptococcus thermophilus와 Lactobacillus bulgaricus와 같은 세균들은 우유를 발효시켜 요구르트를 만드는데에 사용되어 왔다. |
Food and Agriculture Organization of the United Nations, World Health Organization. Probiotics in food: Health and nutritional properties and guidelines for evaluation. FAO/WHO, Rome, Italy (2006)
Gerrard JW, Geddes CA, Reggin PL, Gerrard CD, Horne S. Serum IgE levels in white and metis communities in Saskatchewan. Ann. Allergy 37: 91-100 (1976)
Strachan DP. Hay fever, hygiene, and household size. BMJ 299: 1259-1260 (1989)
Rautava S, Luoto R, Salminen S, Isolauri E. Microbial contact during pregnancy, intestinal colonization and human disease. Nat. Rev. Gastroenterol. Hepatol. 9: 565-576 (2012)
Sudo N, Sawamura S, Tanaka K, Aiba Y, Kubo C, Koga Y. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J. Immunol. 159: 1739-1745 (1997)
Bjorksten B, Naaber P, Sepp E, Mikelsaar M. The intestinal microflora in allergic Estonian and Swedish 2-year-old children. Clin. Exp. Allergy 29: 342-346 (1999)
Bjorksten B, Sepp E, Julge K, Voor T, Mikelsaar M. Allergy development and the intestinal microflora during the first year of life. J. Allergy Clin. Immunol. 108: 516-520 (2001)
Kalliomaki M, Kirjavainen P, Eerola E, Kero P, Salminen S, Isolauri E. Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing. J. Allergy Clin. Immunol. 107: 129-134 (2001)
Ouwehand AC, Isolauri E, He F, Hashimoto H, Benno Y, Salminen S. Differences in Bifidobacterium flora composition in allergic and healthy infants. J. Allergy Clin. Immunol. 108: 144-145 (2001)
Watanabe S, Narisawa Y, Arase S, Okamatsu H, Ikenaga T, Tajiri Y, Kumemura M. Differences in fecal microflora between patients with atopic dermatitis and healthy control subjects. J. Allergy Clin. Immunol. 111: 587-591 (2003)
Kalliomaki M, Salminen S, Arvilommi H, Kero P, Koskinen P, Isolauri E. Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial. Lancet 357: 1076-1079 (2001)
Kalliomaki M, Salminen S, Poussa T, Arvilommi H, Isolauri E. Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial. Lancet 361: 1869-1871 (2003)
Kalliomaki M, Salminen S, Poussa T, Isolauri E. Probiotics during the first 7 years of life: a cumulative risk reduction of eczema in a randomized, placebo-controlled trial. J. Allergy Clin. Immunol. 119: 1019-1021 (2007)
Kim H, Lee SY, Ji GE. Timing of bifidobacterium administration influences the development of allergy to ovalbumin in mice. Biotechnol. Lett. 27: 1361-1367 (2005)
Kim JY, Kwon JH, Ahn SH, Lee SI, Han YS, Choi YO, Lee SY, Ahn KM, Ji GE. Effect of probiotic mix (Bifidobacterium bifidum, Bifidobacterium lactis, Lactobacillus acidophilus) in the primary prevention of eczema: a double-blind, randomized, placebocontrolled trial. Pediatr. Allergy Immunol. 21: e386-393 (2010)
Lee J, Seto D, Bielory L. Meta-analysis of clinical trials of probiotics for prevention and treatment of pediatric atopic dermatitis. J. Allergy Clin. Immunol. 121: 116-121.e11 (2008)
Pelucchi C, Chatenoud L, Turati F, Galeone C, Moja L, Bach JF, La Vecchia C. Probiotics supplementation during pregnancy or infancy for the prevention of atopic dermatitis: a meta-analysis. Epidemiology 23: 402-414 (2012)
Fiocchi A, Pawankar R, Cuello-Garcia C, Ahn K, Al-Hammadi S, Agarwal A, Beyer K, Burks W, Canonica GW, Ebisawa M, Gandhi S, Kamenwa R, Lee BW, Li H, Prescott S, Riva JJ, Rosenwasser L, Sampson H, Spigler M, Terracciano L, Vereda-Ortiz A, Waserman S, Yepes-Nunez JJ, Brozek JL, Schunemann HJ. World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Probiotics. World Allergy Organ J. 8: 4 (2015)
Abrahamsson TR, Jakobsson T, Bottcher MF, Fredrikson M, Jenmalm MC, Bjorksten B, Oldaeus G. Probiotics in prevention of IgE-associated eczema: a double-blind, randomized, placebo-controlled trial. J. Allergy Clin. Immunol. 119: 1174-1180 (2007)
Kukkonen K, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Kuitunen M. Probiotics and prebiotic galacto-oligosaccharides in the prevention of allergic diseases: a randomized, double-blind, placebo-controlled trial. J. Allergy Clin. Immunol. 119: 192-198 (2007)
Majamaa H, Isolauri E. Probiotics: a novel approach in the management of food allergy. J. Allergy Clin. Immunol. 99: 179-185 (1997)
Isolauri E, Arvola T, Sutas Y, Moilanen E, Salminen S. Probiotics in the management of atopic eczema. Clin. Exp. Allergy 30: 1604-1610 (2000)
Rosenfeldt V, Benfeldt E, Nielsen SD, Michaelsen KF, Jeppesen DL, Valerius NH, Paerregaard A. Effect of probiotic Lactobacillus strains in children with atopic dermatitis. J. Allergy Clin. Immunol. 111: 389-395 (2003)
Viljanen M, Savilahti E, Haahtela T, Juntunen-Backman K, Korpela R, Poussa T, Tuure T, Kuitunen M. Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double-blind placebo-controlled trial. Allergy 60: 494-500 (2005)
Weston S, Halbert A, Richmond P, Prescott SL. Effects of probiotics on atopic dermatitis: a randomised controlled trial. Arch. Dis. Child. 90: 892-897 (2005)
Woo SI, Kim JY, Lee YJ, Kim NS, Hahn YS. Effect of Lactobacillus sakei supplementation in children with atopic eczema-dermatitis syndrome. Ann. Allergy. Asthma. Immunol. 104: 343-348 (2010)
Han Y, Kim B, Ban J, Lee J, Kim BJ, Choi BS, Hwang S, Ahn K, Kim J. A randomized trial of Lactobacillus plantarum CJLP133 for the treatment of atopic dermatitis. Pediatr. Allergy Immunol. 23: 667-673 (2012)
Tang ML, Lahtinen SJ, Boyle RJ. Probiotics and prebiotics: clinical effects in allergic disease. Curr. Opin. Pediatr. 22: 626-634 (2010)
Azad MB, Coneys JG, Kozyrskyj AL, Field CJ, Ramsey CD, Becker AB, Friesen C, Abou-Setta AM, Zarychanski R. Probiotic supplementation during pregnancy or infancy for the prevention of asthma and wheeze: systematic review and meta-analysis. BMJ 347: f6471 (2013)
Hol J, van Leer EH, Elink Schuurman BE, de Ruiter LF, Samsom JN, Hop W, Neijens HJ, de Jongste JC, Nieuwenhuis EE. The acquisition of tolerance toward cow's milk through probiotic supplementation: a randomized, controlled trial. J. Allergy Clin. Immunol. 121: 1448-1454 (2008)
Flinterman AE, Knol EF, van Ieperen-van Dijk AG, Timmerman HM, Knulst AC, Bruijnzeel-Koomen CA, Pasmans SG, van Hoffen E. Probiotics have a different immunomodulatory potential in vitro versus ex vivo upon oral administration in children with food allergy. Int. Arch. Allergy Immunol. 143: 237-244 (2007)
Rautava S, Kalliomaki M, Isolauri E. Probiotics during pregnancy and breast-feeding might confer immunomodulatory protection against atopic disease in the infant. J. Allergy Clin. Immunol. 109: 119-121 (2002)
von der Weid T, Bulliard C, Schiffrin EJ. Induction by a lactic acid bacterium of a population of CD4(+) T cells with low proliferative capacity that produce transforming growth factor beta and interleukin-10. Clin. Diagn. Lab. Immunol. 8: 695-701 (2001)
Lammers KM, Brigidi P, Vitali B, Gionchetti P, Rizzello F, Caramelli E, Matteuzzi D, Campieri M. Immunomodulatory effects of probiotic bacteria DNA: IL-1 and IL-10 response in human peripheral blood mononuclear cells. FEMS Immunol. Med. Microbiol. 38: 165-172 (2003)
Pochard P, Gosset P, Grangette C, Andre C, Tonnel AB, Pestel J, Mercenier A. Lactic acid bacteria inhibit TH2 cytokine production by mononuclear cells from allergic patients. J. Allergy Clin. Immunol. 110: 617-623 (2002)
Pohjavuori E, Viljanen M, Korpela R, Kuitunen M, Tiittanen M, Vaarala O, Savilahti E. Lactobacillus GG effect in increasing IFN-gamma production in infants with cow's milk allergy. J. Allergy Clin. Immunol. 114: 131-136 (2004)
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