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Evaluation of Acoustic, Thermal, and Morphological Properties in the Egg White Phantom 원문보기

Journal of biomedical engineering research : the official journal of the Korean Society of Medical & Biological Engineering, v.36 no.1, 2015년, pp.7 - 15  

Kim, Mi-Seon (Department of Biomedical Engineering, Inje University) ,  Kim, Ju-Young (Department of Biomedical Engineering, Inje University) ,  Moon, Dong-Jun (Department of Biomedical Engineering, Inje University) ,  Noh, Si-Cheol (Department of Radiological Science, International University of Korea) ,  Choi, Heung-Ho (Department of Biomedical Engineering, Inje University)

Abstract AI-Helper 아이콘AI-Helper

The egg white phantom is a thermal lesion visualization phantom able to illustrate a thermal lesion. It is often used to evaluate the performance of HIFU and is less expensive than the BSA phantom. This study determined the optimal phantom composition for evaluated therapeutic ultrasound machines by...

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제안 방법

  • In this study, the acoustic and thermal properties of the egg white phantom were evaluated according to the egg white concentration for use as a thermal visualization phantom. The most appropriate phantom concentration for the therapeutic ultrasound evaluation was determined.
  • Table 2. The acoustic property comparisons between the egg white phantom (10-40% egg white), liver tissue, and breast tissue.
  • This study determined the optimal composition for a therapeutic ultrasound phantom by evaluating the acoustic and thermal properties in the phantoms comprising variable egg white concentrations. In addition, the utility of egg white phantom was confirmed by comparing the thermal lesion morphology to that obtained in tissue by therapeutic ultrasonication.

데이터처리

  • Its image recorded using the same digital camera. The images of the lesions were traced by the same operator in ImageJ, and the lesion areas were calculated using a MATLAB program.
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참고문헌 (20)

  1. J.S. Yang, Radiation effect on characteristics of radiationcopolymerized methacryloyl-L-alanine methyl ester-co-2-hydroxypropyl methacrylate hydrogel and biochemical properties of ovomucoid, Daejeon, Korea: Korea Advanced Institute of Science and Technology, 1996, pp. 22-24. 

  2. A.F. Prokop, S. Vaezy, M.L. Noble, P.J. Kaczkowski, R.W. Martin, and L.A. Crum, "Polyacrylamide gel as an acoustic coupling medium for focused ultrasound therapy," Ultrasound Med. Biol., vol. 29, pp. 1351-1358, 2003. 

  3. L.S. Bouchard, and M.J. Bronskill, "Magnetic resonance imaging of thermal coagulation effects in a phantom for calibrating thermal therapy devices," Med. Phys., vol. 27, pp. 1141-1145, 2000. 

  4. C. Lafon, V. Zderic, M.L. Noble, J.C. Yuen, P.J. Kaczkowski, O.A. Sapozhnikov, F. Chavrier, L.A. Crum, and S. Vaezy, "Gel phantom for use in High-intensity focused ultrasound dosimetry," Ultrasound Med. Biol., vol. 31, pp. 1383-1389, 2005. 

  5. H. Ushijima, N. Senoo, J. Suzuki, M. Ichiyanagi, K. Yoshinaka, J. Deguchi, S. Takagi, T. Miyata, and Y. Matsumoto, "Measurements of HIFU-induced Lesions in BSA Gel Phantoms for HIFU Treatment of Varicose Veins of Lower Extremity," in Proc. AIP Conf., Tokyo, Japan, Jun. 2011, pp. 53-58. 

  6. K. Takegami, Y. Kaneko, T. Watanabe, Y. Matsumoto, and H. Nagawa, "Polyacrylamide gel containing egg white as new model for irradiation experiments using focused ultrasound," Ultrasound Med. Biol., vol. 30, pp. 1419-1422, 2004. 

  7. V.A. Khokhlova, M.R. Baile, J.A. Reed, B.W. Cunitz, P.J. Kaczkowski, and L.A. Crum, "Effects of nonlinear propagation, cavitation, and boiling in lesion formation by high intensity focused ultrasound in a gel phantom," J. Acoust. Soc. Am., vol. 119, pp. 1834-1848, 2006. 

  8. J. Gao, J. You, Z. Huang, S. Cochran, and G. Corner, "Simultaneous measurement of thermophysical properties of tissuemimicking phantoms for High Intensity Focused Ultrasound (HIFU) exposures," Int. J. Thermophys., vol. 33, pp. 480- 489, 2012. 

  9. Y. Liu, S. Maruvada, B.A. Herman, and G.R. Harris, "Egg white as a blood coagulation surrogate," J. Acoust. Soc. Am., vol. 128, pp. 480-489, 2010. 

  10. G.W. Divkovic, and J.W. Jenne, "Egg white phantom for HIFU", in Proc. AIP Conf., Kyoto, Japan, Sep. 2004, pp. 143-146. 

  11. G.W. Divkovic, M. Liebler, K. Braun, T. Dreyer, P.E. Huber, and J.W. Jenne, "Thermal properties and changes of acoustic parameters in an egg white phantom during heating and coagulation by High Intensity Focused Ultrasound," Ultrasound Med. Biol., vol. 33, pp. 981-986, 2007. 

  12. C.P. Labuda, and C.C. Church, "Augmentation of HIFUinduced heating with fibers embedded in a phantom," Ultrasound Med. Biol., vol. 3, pp. 442-449, 2011. 

  13. S.R. Davidson, and M.D. Sherar, "Measurement of the thermal conductivity of polyacrylamide tissue equivalent material," Int. J. Hyperthermia, vol. 19, pp. 551-562, 2003. 

  14. M.G. Bini, A. Ignesti, L. Millanta, R. Olmi, N. Rubino, and R. Vanni, "The polyacrylamide as a phantom material for electromagnetic hyperthermia studies," IEEE Trans. Biomed. Eng., vol. BME-31, pp. 317-322, 1984. 

  15. IEC 60601-2-5, Medical electrical equipment-Particular requirements for the basic safety and essential performance of ultrasonic physiotherapy equipment, Geneva, Switzerland: International Electrotechnical Commission, 2009, pp. 21. 

  16. ICRU report 61- Tissue substitutes, phantoms and computational modelling in medical ultrasound, Bethesda, USA: International Commission on Radiation Units and Measurements, 1998, pp. 1-132. 

  17. T.D. Mast, "Empirical relationships between acoustic parameters in human soft tissues," J. Acoust. Soc. Am., vol. 1, pp. 37-42, 2000. 

  18. J.Y. Kim, H.D. Jung, J.H. Min, M.S. Kim, D.J. Moon, J.Y. Kim, S.C. Noh, and H.H. Choi, "A study for the Analysis of thermal denature characteristic on tissue by using Egg-white TMM phantom" in Proc. 48th Biomedical Engineering, Incheon, Korea, Nov. 2013, pp. 57-58. 

  19. C.R. Hill, and G.R. ter Haar, "Review article: High intensity focused ultrasound-potential for cancer treatment," The British J. Radiology, vol. 68, pp. 1296 -1303, 1995. 

  20. D. Haemmerich, I.D. Santos, D.J. Schuttc, J.G. Websterc, and D.M. Mahvid, "In vitro measurements of temperature-dependent specific heat of liver tissue," Medical Engineering & Physics, vol. 28, pp. 194-197, 2006. 

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