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NTIS 바로가기Molecules and cells, v.41 no.6, 2018년, pp.591 - 602
Akter, Hafeza (Molecular Recognition Research Center, Korea Institute of Science and Technology) , Yoon, Jung Hwan (Department of Pathology, College of Medicine, The Catholic University of Korea) , Yoo, Young Sook (Molecular Recognition Research Center, Korea Institute of Science and Technology) , Kang, Min-Jung (Molecular Recognition Research Center, Korea Institute of Science and Technology)
Gastric cancer is the fifth most common type of malignancy worldwide, and the survival rate of patients with advanced-stage gastric cancer is low, even after receiving chemotherapy. Here, we validated neurotensin receptor 1 (NTSR1) as a potential therapeutic target in gastric cancer. We compared NTS...
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Aalinkeel R. Nair B.B. Reynolds J.L. Sykes D.E. Mahajan S.D. Chadha K.C. Schwartz S.A. 2011 Overexpression of MMP-9 contributes to invasiveness of prostate cancer cell line LNCaP Immunol Invest 40 447 464 21391788
Abrahao-Machado L.F. Scapulatempo-Neto C. 2016 HER2 testing in gastric cancer: An update World J Gastroenterol 22 4619 4625 27217694
Akter H. Park M. Kwon O.S. Song E.J. Park W.S. Kang M.J. 2015 Activation of matrix metalloproteinase-9 (MMP-9) by neurotensin promotes cell invasion and migration through ERK pathway in gastric cancer Tumour Biol 36 6053 6062 25724188
Al-Batran S.E. Pauligk C. Wirtz R. Werner D. Steinmetz K. Homann N. Schmalenberg H. Hofheinz R.D. Hartmann J.T. Atmaca A. 2012 The validation of matrix metalloproteinase-9 mRNA gene expression as a predictor of outcome in patients with metastatic gastric cancer Ann Oncol 23 1699 1705 22112973
Alifano M. Souaze F. Dupouy S. Camilleri-Broet S. Younes M. Ahmed-Zaid S.M. Takahashi T. Cancellieri A. Damiani S. Boaron M. 2010 Neurotensin receptor 1 determines the outcome of non-small cell lung cancer Clin Cancer Res 16 4401 4410 20810387
Bakirtzi K. Hatziapostolou M. Karagiannides I. Polytarchou C. Jaeger S. Iliopoulos D. Pothoulakis C. 2011 Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors Gastroenterology 141 1749 1761.e1741 21806946
Bang Y.J. Van Cutsem E. Feyereislova A. Chung H.C. Shen L. Sawaki A. Lordick F. Ohtsu A. Omuro Y. Satoh T. 2010 Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA).: a phase 3, open-label, randomised controlled trial Lancet 376 687 697 20728210
Barretina J. Caponigro G. Stransky N. Venkatesan K. Margolin A.A. Kim S. Wilson C.J. Lehar J. Kryukov G.V. Sonkin D. 2012 The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity Nature 483 603 607 22460905
Carraway R.E. Plona A.M. 2006 Involvement of neurotensin in cancer growth: evidence, mechanisms and development of diagnostic tools Peptides 27 2445 2460 16887236
Correa P. 1996 Helicobacter pylori and gastric cancer: state of the art Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 5 477 481
Dupouy S. Doan V.K. Wu Z. Mourra N. Liu J. De Wever O. Llorca F.P. Cayre A. Kouchkar A. Gompel A. 2014 Activation of EGFR, HER2 and HER3 by neurotensin/neurotensin receptor 1 renders breast tumors aggressive yet highly responsive to lapatinib and metformin in mice Oncotarget 5 8235 8251 25249538
Dupouy S. Viardot-Foucault V. Alifano M. Souaze F. Plu-Bureau G. Chaouat M. Lavaur A. Hugol D. Gespach C. Gompel A. 2009 The neurotensin receptor-1 pathway contributes to human ductal breast cancer progression PloS one 4 e4223 19156213
Elek J. Pinzon W. Park K.H. Narayanan R. 2000 Relevant genomics of neurotensin receptor in cancer Anticancer Res 20 53 58 10769634
Evers B.M. 2006 Neurotensin and growth of normal and neoplastic tissues Peptides 27 2424 2433 16904238
Ferlay J. Soerjomataram I. Dikshit R. Eser S. Mathers C. Rebelo M. Parkin D.M. Forman D. Bray F. 2015 Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012 Int J Cancer 136 E359 386 25220842
Groblewska M. Siewko M. Mroczko B. Szmitkowski M. 2012 The role of matrix metalloproteinases (MMPs)., and their inhibitors (TIMPs). in the development of esophageal cancer Folia Histochemica et Cytobiologica 50 12 19 22532131
Guha S. Rey O. Rozengurt E. 2002 Neurotensin induces protein kinase C-dependent protein kinase D activation and DNA synthesis in human pancreatic carcinoma cell line PANC-1 Cancer Res 62 1632 1640 11912133
Hasan M. Seo J.E. Rahaman K.A. Kang M.J. Jung B.H. Kwon O.S. 2016 Increased levels of brain serotonin correlated with MMP-9 activity and IL-4 levels resulted in severe experimental autoimmune encephalomyelitis (EAE). in obese mice Neuroscience 319 168 182 26820599
Hwang T.L. Changchien T.T. Wang C.C. Wu C.M. 2014 Claudin-4 expression in gastric cancer cells enhances the invasion and is associated with the increased level of matrix metalloproteinase-2 and -9 expression Oncol Lett 8 1367 1371 25120725
Kang M.H. Kim J.S. Seo J.E. Oh S.C. Yoo Y.A. 2010 BMP2 accelerates the motility and invasiveness of gastric cancer cells via activation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway Exp Cell Res 316 24 37 19835871
Kim Y.M. Ku M.J. Son Y.J. Yun J.M. Kim S.H. Lee S.Y. 2013 Anti-metastatic effect of cantharidin in A549 human lung cancer cells Arch Pharm Res 36 479 484 23435912
Knall C. Young S. Nick J.A. Buhl A.M. Worthen G.S. Johnson G.L. 1996 Interleukin-8 regulation of the Ras/Raf/mitogen-activated protein kinase pathway in human neutrophils J Biol Chem 271 2832 2838 8576262
Leifler K.S. Svensson S. Abrahamsson A. Bendrik C. Robertson J. Gauldie J. Olsson A.K. Dabrosin C. 2013 Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer J Immunol 190 4420 4430 23509357
Li H. Zhang K. Liu L.H. Ouyang Y. Bu J. Guo H.B. Xiao T. 2014 A systematic review of matrix metalloproteinase 9 as a biomarker of survival in patients with osteosarcoma Tumour Biol 35 5487 5491 24577891
Maatta M. Soini Y. Liakka A. Autio-Harmainen H. 2000 Differential expression of matrix metalloproteinase (MMP).-2, MMP-9, and membrane type 1-MMP in hepatocellular and pancreatic adenocarcinoma: implications for tumor progression and clinical prognosis Clin Cancer Res 6 2726 2734 10914717
Muller K.M. Tveteraas I.H. Aasrum M. Odegard J. Dawood M. Dajani O. Christoffersen T. Sandnes D.L. 2011 Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells BMC Cancer 11 421 21961726
Nagarajan D. Melo T. Deng Z. Almeida C. Zhao W. 2012 ERK/GSK3beta/Snail signaling mediates radiation-induced alveolar epithelial-to-mesenchymal transition Free Radic Biol Med 52 983 992 22198183
Ocejo-Garcia M. Ahmed S.I. Coulson J.M. Woll P.J. 2001 Use of RT-PCR to detect co-expression of neuropeptides and their receptors in lung cancer Lung Cancer (Amsterdam, Netherlands) 33 1 9
Pfaffl M.W. 2001 A new mathematical model for relative quantification in real-time RT-PCR Nucleic Acids Res 29 e45 11328886
Pryczynicz A. Guzinska-Ustymowicz K. Dymicka-Piekarska V. Czyzewska J. Kemona A. 2007 Expression of matrix metalloproteinase 9 in pancreatic ductal carcinoma is associated with tumor metastasis formation Folia histochemica et cytobiologica 45 37 40 17378244
Rovere C. Barbero P. Maoret J.J. Laburthe M. Kitabgi P. 1998 Pro-neurotensin/neuromedin N expression and processing in human colon cancer cell lines Biochem Biophys Res Commun 246 155 159 9600085
Seethalakshmi L. Mitra S.P. Dobner P.R. Menon M. Carraway R.E. 1997 Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations Prostate 31 183 192 9167771
Shimizu S. Tsukada J. Sugimoto T. Kikkawa N. Sasaki K. Chazono H. Hanazawa T. Okamoto Y. Seki N. 2008 Identification of a novel therapeutic target for head and neck squamous cell carcinomas: a role for the neurotensin-neurotensin receptor 1 oncogenic signaling pathway Int J Cancer 123 1816 1823 18661521
Sier C.F. Kubben F.J. Ganesh S. Heerding M.M. Griffioen G. Hanemaaijer R. van Krieken J.H. Lamers C.B. Verspaget H.W. 1996 Tissue levels of matrix metalloproteinases MMP-2 and MMP-9 are related to the overall survival of patients with gastric carcinoma Brit J Cancer 74 413 417 8695357
Sillem M. Prifti S. Koumouridis A. Runnebaum B. 1999 Invasiveness corresponds to differentiation rather than to proteinase secretion in endometrial cancer cell lines Eur J Gynaecol Oncol 20 367 370 10609496
Souaze F. Dupouy S. Viardot-Foucault V. Bruyneel E. Attoub S. Gespach C. Gompel A. Forgez P. 2006 Expression of neurotensin and NT1 receptor in human breast cancer: a potential role in tumor progression Cancer Res 66 6243 6249 16778199
Valerie N.C. Casarez E.V. Dasilva J.O. Dunlap-Brown M.E. Parsons S.J. Amorino G.P. Dziegielewski J. 2011 Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation Cancer Res 71 6817 6826 21903767
Venkatakrishnan G. Salgia R. Groopman J.E. 2000 Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells J Biol Chem 275 6868 6875 10702246
Vincent J.P. Mazella J. Kitabgi P. 1999 Neurotensin and neurotensin receptors Trends Pharmacol Sci 20 302 309 10390649
Wagner A.D. Grothe W. Haerting J. Kleber G. Grothey A. Fleig W.E. 2006 Chemotherapy in advanced gastric cancer: a systematic review and meta-analysis based on aggregate data J Clin Oncol 24 2903 2909 16782930
Wang A.X. Qi X.Y. 2013 Targeting RAS/RAF/MEK/ERK signaling in metastatic melanoma IUBMB life 65 748 758 23893853
Wang J.G. Li N.N. Li H.N. Cui L. Wang P. 2011 Pancreatic cancer bears overexpression of neurotensin and neurotensin receptor subtype-1 and SR 48692 counteracts neurotensin induced cell proliferation in human pancreatic ductal carcinoma cell line PANC-1 Neuropeptides 45 151 156 21272935
Weiss M.B. Abel E.V. Mayberry M.M. Basile K.J. Berger A.C. Aplin A.E. 2012 TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cells Cancer Res 72 6382 6392 23222305
Yu J. Ren X. Chen Y. Liu P. Wei X. Li H. Ying G. Chen K. Winkler H. Hao X. 2013 Dysfunctional activation of neurotensin/IL-8 pathway in hepatocellular carcinoma is associated with increased inflammatory response in microenvironment, more epithelial mesenchymal transition in cancer and worse prognosis in patients PloS one 8 e56069 23418512
Zhao D. Pothoulakis C. 2006 Effects of NT on gastrointestinal motility and secretion, and role in intestinal inflammation Peptides 27 2434 2444 16872719
Zheng S. Chang Y. Hodges K.B. Sun Y. Ma X. Xue Y. Williamson S.R. Lopez-Beltran A. Montironi R. Cheng L. 2010 Expression of KISS1 and MMP-9 in non-small cell lung cancer and their relations to metastasis and survival Anticancer Res 30 713 718 20392988
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