다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기
Biomolecules & therapeutics, v.26 no.4, 2018년, pp.399 - 408
Nagashima, Fumiaki (Department of Anesthesiology, Tokyo Medical University) , Nishiyama, Ryohta (Department of Anesthesiology, Tokyo Medical University) , Iwao, Beniko (Department of Psychiatry, Tokyo Medical University) , Kawai, Yuiko (Institute of Medical Science, Tokyo Medical University) , Ishii, Chikanao (Institute of Medical Science, Tokyo Medical University) , Yamanaka, Tsuyoshi (Department of Molecular Preventive Medicine, Tokyo Medical University) , Uchino, Hiroyuki (Department of Anesthesiology, Tokyo Medical University) , Inazu, Masato (Institute of Medical Science, Tokyo Medical University)
AI-Helper
In this study, we examined the molecular and functional characterization of choline uptake in the human esophageal cancer cells. In addition, we examined the influence of various drugs on the transport of [
Ackerstaff E Glunde K Bhujwalla ZM 2003 Choline phospholipid metabolism: a target in cancer cells? J Cell Biochem 90 525 533 10.1002/jcb.10659 14523987
Albright CD Liu R Bethea TC Da Costa KA Salganik RI Zeisel SH 1996 Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture FASEB J 10 510 516 10.1096/fasebj.10.4.8647350 8647350
Balassiano K Lima S Jenab M Overvad K Tjonneland A Boutron-Ruault MC Clavel-Chapelon F Canzian F Kaaks R Boeing H Meidtner K Trichopoulou A Laglou P Vineis P Panico S Palli D Grioni S Tumino R Lund E Buenode-Mesquita HB Numans ME Peeters PH Ramon Quirós J Sánchez MJ Navarro C Ardanaz E Dorronsoro M Hallmans G Stenling R Ehrnström R Regner S Allen NE Travis RC Khaw KT Offerhaus GJ Sala N Riboli E Hainaut P Scoazec JY Sylla BS Gonzalez CA Herceg Z 2011 Aberrant DNA methylation of cancer-associated genes in gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST) Cancer Lett 311 85 95 10.1016/j.canlet.2011.06.038 21831520
Bertagna F Bertoli M Treglia G Manenti S Salemme M Giubbini R 2014 Incidental 11 C-Choline PET/CT uptake due to Esophageal carcinoma in a patient studied for prostate cancer Clin Nucl Med 39 e442 e444 10.1097/RLU.0000000000000334 24561683
Eliyahu G Kreizman T Degani H 2007 Phosphocholine as a biomarker of breast cancer: molecular and biochemical studies Int. J. Cancer 120 1721 1730 10.1002/ijc.22293 17236204
Fujita T Shimada A Okada N Yamamoto A 2006 Functional characterization of Na + -independent choline transport in primary cultures of neurons from mouse cerebral cortex Neurosci Lett 393 216 221 10.1016/j.neulet.2005.09.069 16239069
García JR Ponce A Canales M Ayuso J Moragas M Soler M 2014 Detection of second tumors in 11 C-choline PET/CT studies performed due to biochemical recurrence of prostate cancer Rev Esp Med Nucl Imagen Mol 33 28 31 23499124
Gllies RJ Morse DL 2005 In vivo magnetic resonance spectroscopy in cancer Annu Rev Biomed Eng 7 287 326 10.1146/annurev.bioeng.7.060804.100411 16004573
Glunde K Jiang L Moestue SA Gribbestad IS 2011 MRS and MRSI guidance in molecular medicine: targeting and monitoring of choline and glucose metabolism in cancer NMR Biomed 24 673 690 10.1002/nbm.1751 3146026 --> 21793073
Glunde K Jacobs MA Bhujwalla ZM 2006 Choline metabolism in cancer: implications for diagnosis and therapy Expert Rev Mol Diagn 6 821 829 10.1586/14737159.6.6.821 17140369
Inazu M 2014 Choline transporter-like proteins CTLs/SLC44 family as a novel molecular target for cancer therapy Biopharm Drug Dispos 35 431 449 10.1002/bdd.1892 24532461
Inazu M Takeda H Matsumiya T 2005 Molecular and functional characterization of an Na + -independent choline transporter in rat astrocytes J Neurochem 94 1427 1437 10.1111/j.1471-4159.2005.03299.x 16000150
Inazu M Yamada T Kubota N Yamanaka T 2013 Functional expression of choline transporter-like protein 1 (CTL1) in small cell lung carcinoma cells: a target molecule for lung cancer therapy Pharmacol Res 76 119 131 10.1016/j.phrs.2013.07.011 23948665
Iwao B Yara M Hara N Kawai Y Yamanaka T Nishihara H Inoue T Inazu M 2016 Functional expression of choline transporter like-protein 1 (CTL1) and CTL2 in human brain microvascular endothelial cells Neurochem Int 93 40 50 10.1016/j.neuint.2015.12.011 26746385
Kaelin WG Jr McKnight SL 2013 Influence of metabolism on epigenetics and disease Cell 153 56 69 10.1016/j.cell.2013.03.004 3775362 --> 23540690
Kaplan CP Porter RK Brand MD 1993 The choline transporter is the major site of control of choline oxidation in isolated rat liver mitochondria FEBS Lett 321 24 26 10.1016/0014-5793(93)80613-Y 8467907
Kommareddi PK Nair TS Thang LV Galano MN Babu E Ganapathy V Kanazawa T McHugh JB Carey TE 2010 Isoforms, expression, glycosylation, and tissue distribution of CTL2/SLC44A2 Protein J 29 417 426 10.1007/s10930-010-9268-y 2975550 --> 20665236
Kouji H Inazu M Yamada T Tajima H Aoki T Matsumiya T 2009 Molecular and functional characterization of choline transporter in human colon carcinoma HT-29 cells Arch Biochem Biophys 483 90 98 10.1016/j.abb.2008.12.008 19135976
Liu D Hutchinson OC Osman S Price P Workman P Aboagye EO 2002 Use of radiolabelled choline as a pharmacodynamic marker for the signal transduction inhibitor geldanamycin. Br. J. Cancer 87 783 789 10.1038/sj.bjc.6600558 2364261 --> 12232764
Michel V Bakovic M 2012 The ubiquitous choline transporter SLC44A1 Cent Nerv Syst Agents Med Chem 12 70 81 10.2174/187152412800792733 22483272
Nair TS Kozma KE Hoefling NL Kommareddi PK Ueda Y Gong TW Lomax MI Lansford CD Telian SA Satar B Arts HA El-Kashlan HK Berryhill WE Raphael Y Carey TE 2004 Identification and characterization of choline transporter-like protein 2, an inner ear glycoprotein of 68 and 72 kDa that is the target of antibody-induced hearing loss J Neurosci 24 1772 1779 10.1523/JNEUROSCI.5063-03.2004 14973250
Nishiyama R Nagashima F Iwao B Kawai Y Inoue K Midori A Yamanaka T Uchino H Inazu M 2016 Identification and functional analysis of choline transporter in tongue cancer: A novel molecular target for tongue cancer therapy J Pharmacol Sci 131 101 109 10.1016/j.jphs.2016.04.022 27262903
O’Donoghue N Sweeney T Donagh R Clarke KJ Porter RK 2009 Control of choline oxidation in rat kidney mitochondria. Biochim Biophys. Acta 1787 1135 1139
Ossani G Dalghi M Repetto M 2007 Oxidative damage lipid peroxidation in the kidney of choline-deficient rats Front Biosci 12 1174 1183 10.2741/2135 17127370
Porter RK Scott JM Brand MD 1992 Choline transport into rat liver mitochondria. Characterization and kinetics of a specific transporter J Biol Chem 267 14637 14646 1634511
Shimada Y Imamura M Wagata T Yamaguchi N Tobe T 1992 Characterization of 21 newly established esophageal cancer cell lines Cancer 69 277 284 10.1002/1097-0142(19920115)69:2 3.0.CO;2-C 1728357
Tachimori Y Ozawa S Numasaki H Fujishiro M Matsubara H Oyama T Shinoda M Toh Y Udagawa H Uno T 2016 Comprehensive registry of esophageal cancer in Japan, 2009 Esophagus 13 110 137 10.1007/s10388-016-0531-y 4824839 --> 27110229
Taguchi C Inazu M Saiki I Yara M Hara N Yamanaka T Uchino H 2014 Functional analysis of [methyl- 3 H]choline uptake in glioblastoma cells: influence of anti-cancer and central nervous system drugs Biochemical Pharmacol 88 303 312 10.1016/j.bcp.2014.01.033
Tian M Zhang H Oriuchi T Higuchi T Endo K 2004 Comparison of 11 C-choline PET and FDG PET for the differential diagnosis of malignant tumors Eur. J. Nucl. Med. Mol. Imaging 31 1064 1072 15014903
Uchida Y Inazu M Takeda H Yamada T Tajima H Matsumiya T 2009 Expression and functional characterization of choline transporter in human keratinocytes J Pharmacol Sci 109 102 109 10.1254/jphs.08291FP 19122366
Wang T Li J Chen F Zhao Y He X Wan D Gu J 2007 Choline transporters in human lung adenocarcinoma: expression and functional implications Acta Biochim Biophys Sin (Shanghai) 39 668 674 10.1111/j.1745-7270.2007.00323.x 17805461
Xu XC 2009 Risk factors and gene expression in esophageal cancer Methods Mol Biol 471 335 360 10.1007/978-1-59745-416-2_17 19109788
Yabuki M Inazu M Yamada T Tajima H Matsumiya T 2009 Molecular and functional characterization of choline transporter in rat renal tubule epithelial NRK-52E cells Arch Biochem Biophys 485 88 96 10.1016/j.abb.2009.02.007 19236841
Yamada T Inazu M Tajima H Matsumiya T 2011 Functional expression of choline transporter-like protein 1 (CTL1) in human neuroblastoma cells and its link to acetylcholine synthesis Neurochem Int 58 354 365 10.1016/j.neuint.2010.12.011 21185344
Yara M Iwao B Hara N Yamanaka T Uchino H Inazu M 2015 Molecular and functional characterization of choline transporter in the human trophoblastic cell line JEG-3 cells Placenta 36 631 637 10.1016/j.placenta.2015.03.010 25896522
Yen CL Mar MH Zeisel SH 1999 Choline deficiency-induced apoptosis in PC12 cells is associated with diminished membrane phosphatidylcholine and sphingomyelin, accumulation of ceramide and diacylglycerol, and activation of a caspase FASEB J 13 135 142 10.1096/fasebj.13.1.135 9872938
Zhang Y 2013 Epidemiology of esophageal cancer World J Gastroenterol 19 5598 5606 10.3748/wjg.v19.i34.5598 3769895 --> 24039351
Copyright KISTI. All Rights Reserved.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.