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Incidentally Discovered Solitary Gastrointestinal Polyp with Pathological Significance in Children: Four Case Reports 원문보기

Pediatric gastroenterology, hepatology & nutrition, v.21 no.3, 2018년, pp.209 - 213  

Han, Sang-eun (Department of Pediatrics, Hanyang University College of Medicine) ,  Chang, Jiyeon (Department of Pediatrics, Hanyang University College of Medicine) ,  Paik, Seung Sam (Department of Pathology, Hanyang University College of Medicine) ,  Kim, Yong Joo (Department of Pediatrics, Hanyang University College of Medicine)

Abstract AI-Helper 아이콘AI-Helper

Most solitary gastrointestinal (GI) polyps in children are either inflammatory or hamartomatous. Solitary hyperplastic polyp, sentinel polyp and solitary adenomatous polyp have been occasionally diagnosed in adults, but very rarely reported in Korean children. We recently came across a case with ade...

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제안 방법

  • Following the diagnosis, tumor marker tests (CA-125, αFP, β-HCG) were performed, and they were normal.
  • Additionally, multiple cystic lesions were found on pelvic ultrasonography, but these were not considered the direct cause of her chronic abdominal pain. Medical treatment was administered for her UGI mucosal lesions. The rectal polyp was removed using cold snare.

대상 데이터

  • A 13-year-old boy presented with abdominal pain and diarrhea. Laboratory examination revealed mild leukocytosis of 10,800/mm3 with polymorphonuclear cell 81%, hemoglobin level of 14.
  • A 15-year-old girl presented with recurrent abdominal pain for 6 years. Initial laboratory workup revealed a white blood cell count (WBC) of 5,000/mm3 with 66% neutrophils, hemoglobin level of 12.
  • An 18-year-old girl presented with fatigue, anorexia, indigestion, constipation, and postprandial abdominal pain. She was diagnosed with cecal diverticulosis 5 years earlier, and Helicobacter pylori (HP)- positive gastric ulcer 1 year earlier.
  • She was negative to HP at the time of polypectomy. The pathological finding was HPP (Fig. 1C). She was treated with medicines for her UGI mucosal lesions and the previous GI symptoms were resolved.
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참고문헌 (17)

  1. 1 Horrilleno EG Eckert C Ackerman LV Polyps of the rectum and colon in children Cancer 1957 10 1210 1220 13489673 

  2. 2 Friedman CJ Fechner RE A solitary juvenile polyp with hyperplastic and adenomatous glands Dig Dis Sci 1982 27 946 948 7117079 

  3. 3 Goddard AF Badreldin R Pritchard DM Walker MM Warren B on behalf of the British Society of Gastroenterology The management of gastric polyp Gut 2010 59 1270 1276 20675692 

  4. 4 Dirschmid K Platz-Baudin C Stolte M Why is the hyperplastic polyp a marker for the precancerous condition of the gastric mucosa? Virchows Arch 2006 448 80 84 16189701 

  5. 5 Lim MS Seo JK Ko JS Yang HR Kang GH Kim WS Clinical, endoscopic and pathologic findings of colonic polyposis in Korean children Korean J Pediatr Gastroenterol Nutr 2010 13 154 163 

  6. 6 Kim JW Song JY Lee HK Yun HS Yang I Shim JW A case of isolated adenomatous polyp of rectum in a child: tubulovillous adenoma Korean J Pediatr Gastroenterol Nutr 1999 2 250 255 

  7. 7 Lee KS Lee SH Myong NH Peutz-Jeghers syndrome with adenomatous change in a fifteen-month-old boy Korean J Gastroenterol 2015 66 106 110 26289244 

  8. 8 Hongo M Fujimoto K Gastric Polyps Study Group Incidence and risk factor of fundic gland polyp and hyperplastic polyp in long-term proton pump inhibitor therapy: a prospective study in Japan J Gastroenterol 2010 45 618 624 20177714 

  9. 9 Pashankar DS Israel DM Gastric polyps and nodules in children receiving long-term omeprazole therapy J Pediatr Gastroenterol Nutr 2002 35 658 662 12454582 

  10. 10 Ohkusa T Takashimizu I Fujiki K Suzuki S Shimoi K Horiuchi T Disappearance of hyperplastic polyps in the stomach after eradication of Helicobacter pylori. A randomized, clinical trial Ann Intern Med 1998 129 712 715 9841603 

  11. 11 Nakamura T Nakano G Histopathological classification and malignant change in gastric polyps J Clin Pathol 1985 38 754 764 4019798 

  12. 12 Park SJ Kim HG Yang JH Song HJ Jin SY Ryu CB A case of adenocarcinoma arising in hyperplastic polyp in the stomach Korean J Gastrointest Endosc 2003 27 153 157 

  13. 13 Fry LC Lazenby AJ Lee DH Mönkemüller K Signet-ring-cell adenocarcinoma arising from a hyperplastic polyp in the stomach Gastrointest Endosc 2005 61 493 495 15758936 

  14. 14 Ryu HS Shin SR Kim KH Seo GS Choi SC A case of a gastric hyperplastic polyp with a signet ring cell carcinoma Korean J Gastrointest Endosc 2008 36 376 379 

  15. 15 Han AR Sung CO Kim KM Park CK Min BH Lee JH The clinicopathological features of gastric hyperplastic polyps with neoplastic transformations: a suggestion of indication for endoscopic polypectomy Gut Liver 2009 3 271 275 20431760 

  16. 16 Abraham SC Singh VK Yardley JH Wu TT Hyperplastic polyps of the esophagus and esophagogastric junction: histologic and clinicopathologic findings Am J Surg Pathol 2001 25 1180 1187 11688578 

  17. 17 Bishop PR Nowicki MJ Subramony C Parker PH The inflammatory polyp-fold complex in children J Clin Gastroenterol 2002 34 229 232 11873101 

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