[논문]Solitary mastocytoma presenting at birth

Ha, Non Hyeon; Lee, Yoo Jung; Park, Myong Chul; Lee, Il Jae; Kim, Sue Min; Park, Dong Ha

doi:10.7181/acfs.2018.01508

Solitary mastocytoma presenting at birth 원문보기

Archives of craniofacial surgery : ACFS, v.19 no.2, 2018년, pp.127 - 130

Ha, Non Hyeon (Department of Plastic and Reconstructive Surgery, Ajou University Hospital) , Lee, Yoo Jung (Department of Plastic and Reconstructive Surgery, Ajou University Hospital) , Park, Myong Chul (Department of Plastic and Reconstructive Surgery, Ajou University Hospital) , Lee, Il Jae (Department of Plastic and Reconstructive Surgery, Ajou University Hospital) , Kim, Sue Min (Department of Plastic and Reconstructive Surgery, Ajou University Hospital) , Park, Dong Ha (Department of Plastic and Reconstructive Surgery, Ajou University Hospital)

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Mastocytosis is a rare disease which occurs in both children and adults, and it can manifest as a solitary or multiple skin lesions. Both can cause cutaneous or systemic symptoms. Because of the heterogeneity of clinical presentation of mastocytosis and its rare prevalence, it can be hard to suspect the mastocytosis at the first time. Most solitary mastocytomas are about 1-5 cm in diameter and have features of brownish-yellow, minimally elevated plaques with a smooth shiny surface. This article presents a case of solitary mastocytoma which occurred in neonate and that we treated through surgical excision. In histopathological examination, it consisted of c-kit-positive mast cells. Although pediatric cutaneous mastocytosis might regress spontaneously, clinicians should keep in mind that it could be associated with systemic mastocytosis which involves hematopoietic system.

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A 13-day-old neonate came to Ajou University Hospital with oval-shaped brownish skin lesion on her dorsum of nose (Fig. 1). At first, it was considered as a benign lesion, so we suggested her parents wait until she becomes tolerable to the general anesthesia for removal.
Thus, we performed excisional biopsy instead of topical corticosteroid therapy. The patient was extremely young, even she was a 13-day-old neonate. And usually, in cutaneous mastocytosis, therapy is conservative care because the prognosis of cutaneous mastocytosis is good.

참고문헌 (8)

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2 Sukesh MS Dandale A Dhurat R Sarkate A Ghate S Case report: solitary mastocytoma treated successfully with topical tacrolimus F1000Res 2014 3 181 25210620

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3 Caplan RM The natural course of urticaria pigmentosa: analysis and follow-up of 112 cases Arch Dermatol 1963 87 146 57 14018418

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4 Chargin L Sachs PM Urticaria pigmentosa appearing as a solitary nodular lesion AMA Arch Derm Syphilol 1954 69 345 55 13137605
5 Heide R Beishuizen A De Groot H Den Hollander JC Van Doormaal JJ De Monchy JG Mastocytosis in children: a protocol for management Pediatr Dermatol 2008 25 493 500 18789103
6 Abid A Malone MA Curci K Mastocytosis Prim Care 2016 43 505 18 27545739

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7 UpToDate Mastocytosis (cutaneous and systemic): evaluation and diagnosis in children [Internet] Waltham, MA UpToDate [cited 2018 Apr 4]. Available from: https://www.uptodate.com/contents/mastocytosis-cutaneous-and-systemic-evaluation-and-diagnosis-in-children
8 Weiler CR Butterfield J Mast cell sarcoma: clinical management Immunol Allergy Clin North Am 2014 34 423 32 24745684

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DOI : 10.7181/acfs.2018.01508 [무료]
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PubMed Central : 저널 > 논문 [무료]
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