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NTIS 바로가기한국균학회지 = The Korean journal of mycology, v.48 no.1, 2020년, pp.15 - 27
황혜진 (국립낙동강생물자원관 균류연구팀) , 문혜연 (국립낙동강생물자원관 균류연구팀) , 황병수 (국립낙동강생물자원관 동식물활용연구팀) , 남영호 (국립낙동강생물자원관 환경미생물연구팀) , 정유진 (국립낙동강생물자원관 환경미생물연구팀)
In screening for antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) KCCM 40510 and Bacillus cereus KCTC 3624, NNIBRFG5039 was isolated from the air in Sangju-si, Gyeongsangbuk-do. Based on a high sequence similarity of the internal transcribed spacer (ITS) region, NNIB...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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다제내성균의 예는 무엇이 있는가? | Fleming이 Penicillium notatum으로부터 처음 발견되어 널리 사용되었으나, 1950년대 초 penicillin에 의하여 사멸되지 않는 Staphylococcus 균주가 출현하기 시작하였다[1]. 특히 methicillin-resistant Staphylococcus aureus (MRSA)는 그람양성균으로 원내 감염의 원인균이며, penicillin 뿐만 아니라, cephalosporin, carbapenem, monobactam 등 대다수의 항생제에 치료가 되지 않는 다제내성을 나타내는 것으로 보고되었다[2]. 최근 항생제 내성 및 다제 내성 세균의 증가로 인해 다제내성균에 대하여 항균효과를 가지는 새로운 항생물질의 개발이 절실히 요구되고있다. | |
항생제는 무엇에 사용되는가? | 항생물질은 "미생물에 의해 생산되고, 다른 미생물의 발육을 억제하는 물질"로 정의되며, 이러한 물질로 만든 병원성 박테리아 감염의 치료 및 예방에 사용되는 약을 항생제라고 한다. 인류 최초의 항생제 penicillin은 1928년 영국의 A. |
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