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NTIS 바로가기대한한방내과학회지 = The journal of internal Korean medicine, v.41 no.4, 2020년, pp.612 - 623
김민지 (대전대학교 한의과대학 심계내과학교실) , 원서영 (대전대학교 한의과대학 심계내과학교실) , 김해융 (대전대학교 한의과대학 심계내과학교실) , 유주영 (대전대학교 한의과대학 심계내과학교실) , 정은선 (대전대학교 한의과대학 심계내과학교실) , 유호룡 (대전대학교 한의과대학 심계내과학교실) , 설인찬 (대전대학교 한의과대학 심계내과학교실) , 김윤식 (대전대학교 한의과대학 심계내과학교실)
Objectives: The aim of this research was to investigate and review the trends in recent clinical studies of multiple system atrophy (MSA) in China. Methods: We searched for clinical studies discussing Oriental medicine-based treatments for MSA in the China National Knowledge Infrastructure (CNKI) da...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
다계통 위축증이란 무엇인가? | 다계통 위축증(Multiple system atrophy)는 뇌의 여러 계통에 위축이 발생하는 진행성 퇴행성 뇌질환으로 임상적으로 자율신경계 증상과 파킨슨 증상, 소뇌실조 증상이 복합적으로 나타난다. 다계통위축증은 다양하고 복합적인 증상이 나타나는 특성상 진단이 어려워 파킨슨병, 특발성 소뇌실조증 등으로 오인되기 쉽다1,2. | |
다계통 위축증에 대한 치료는 무엇인가? | 다계통 위축증은 예후가 불량해 신경퇴행이 빠르게 진행하여 증상 발생으로부터 6-10년 정도 생존한다고 보고되고 있으나2, 아직까지 질병의 발생이나 진행을 막을 수 있는 효과적인 치료법은 알려져 있지 않고, 대증치료 위주의 약물요법, 재활치료에 의한 기능유지, 전신관리를 중심으로 치료가 진행되고 있는 실정이다4. | |
다계통 위축증은 임상적으로 어떻게 분류할 수 있는가? | 임상적으로 자율신경계의 증상이 두드러지는 MSA-A type, 파킨슨 증상이 두드러지는 MSA-P type, 그리고 소뇌증상이 두드러지는 MSA-C type으로 분류할 수 있으나 이들 모두에서 공통적으로 비정상적인 알파 시누클레인을 포함한 아교세포질포함체(gli cytoplasmic inclusion)라는 병리소견이 있고, 자율신경계 증상이 초기에 동반된다는 사실이 밝혀진 후 MSA-A type은 잘 사용하지 않고 통합하여 MSA로 부르고 있다1-3. |
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