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[해외논문] Detection of Antigen-Specific T Cells with Multivalent Soluble Class II MHC Covalent Peptide Complexes 원문보기

Immunity, v.8 no.6, 1998년, pp.675 - 682  

Crawford, Frances (Howard Hughes Medical Institute, Division of Basic Immunology, National Jewish Medical and Research Center, Denver, Colorado 80206, USA) ,  Kozono, Haruo (Howard Hughes Medical Institute, Division of Basic Immunology, National Jewish Medical and Research Center, Denver, Colorado 80206, USA) ,  White, Janice (Howard Hughes Medical Institute, Division of Basic Immunology, National Jewish Medical and Research Center, Denver, Colorado 80206, USA) ,  Marrack, Philippa (Departments of Immunology and Medicine, Biophysics, and Genetics, University of Colorado Health Science Center, Denver, Colorado 80262, USA) ,  Kappler, John (Departments of Immunology and Medicine, Biophysics, and Genetics, University of Colorado Health Science Center, Denver, Colorado 80262, USA)

Abstract AI-Helper 아이콘AI-Helper

AbstractMultimeric soluble MHC class II molecules stably occupied with covalently attached peptides bind with appropriate specificity to T cell hybridomas and T cells from T cell receptor transgenic mice. There is a direct correlation between soluble T cell receptor affinity for monomeric MHC/peptid...

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