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[해외논문] Requirement of the Chemokine Receptor CXCR3 for Acute Allograft Rejection

The Journal of experimental medicine, v.192 no.10, 2000년, pp.1515 - 1520  

Hancock, Wayne W. (Millennium Pharmaceuticals, Incorporated, Cambridge, Massachusetts 02139) ,  Lu, Bao (Perlmutter Laboratory, Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115) ,  Gao, Wei (Millennium Pharmaceuticals, Incorporated, Cambridge, Massachusetts 02139) ,  Csizmadia, Vilmos (Millennium Pharmaceuticals, Incorporated, Cambridge, Massachusetts 02139) ,  Faia, Kerrie (Millennium Pharmaceuticals, Incorporated, Cambridge, Massachusetts 02139) ,  King, Jennifer A. (Millennium Pharmaceuticals, Incorporated, Cambridge, Massachusetts 02139) ,  Smiley, Stephen T. (Millennium Pharmaceuticals, Incorporated, Cambridge, Massachusetts 02139) ,  Ling, Mai (Perlmutter Laboratory, Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115) ,  Gerard, Norma P. (Perlmutter Laboratory, Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115) ,  Gerard, Craig (Perlmutter Laboratory, Children's Hospital and Harvard Medical School, Boston, Massachusetts 02115)

Abstract AI-Helper 아이콘AI-Helper

Chemokines provide signals for activation and recruitment of effector cells into sites of inflammation, acting via specific G protein–coupled receptors. However, in vitro data demonstrating the presence of multiple ligands for a given chemokine receptor, and often multiple receptors for a giv...

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참고문헌 (21)

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  6. Zlotnik A. Yoshie O. Chemokinesa new classification system and their role in immunity Immunity. 12 2000 121 127 10714678 

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  9. Cole K.E. Strick C.A. Paradis T.J. Ogborne K.T. Loetscher M. Gladue R.P. Lin W. Boyd J.G. Moser B. Wood D.E. Interferon-inducible T cell alpha chemoattractant (I-TAC)a novel non-ELR CXC chemokine with potent activity on activated T cells through selective high affinity binding to CXCR3 J. Exp. Med. 187 1998 2009 2021 9625760 

  10. Luster A.D. Ravetch J.V. Biochemical characterization of a gamma interferon–inducible cytokine (IP-10) J. Exp. Med. 166 1987 1084 1097 2443596 

  11. Farber J.M. HuMiga new human member of the chemokine family of cytokines Biochem. Biophys. Res. Commun. 192 1993 223 230 8476424 

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  13. Rani M.R.S. Foster G.R. Leung S. Leaman D. Stark G.R. Ransohoff R.M. Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha J. Biol. Chem. 271 1996 22878 22884 8798467 

  14. Lu B. Humbles A. Bota D. Gerard C. Moser B. Soler D. Luster A.D. Gerard N.P. Structure and function of the murine chemokine receptor CXCR3 Eur. J. Immunol. 29 1999 3804 3812 10556837 

  15. Gao W. Topham P.S. King J.A. Smiley S.T. Csizmadia V. Lu B. Gerard C.J. Hancock W.W. Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection J. Clin. Invest. 105 2000 35 44 10619859 

  16. Hancock W.W. Sayegh M.H. Zheng X.G. Peach R. Linsley P.S. Turka L.A. Costimulatory function and expression of CD40 ligand, CD80, and CD86 in vascularized murine cardiac allograft rejection Proc. Natl. Acad. Sci. USA. 93 1996 13967 13972 8943044 

  17. Hancock W.W. Buelow R. Sayegh M.H. Turka L.A. Antibody-induced transplant arteriosclerosis is prevented by graft expression of anti-oxidant and anti-apoptotic genes Nat. Med. 4 1998 1392 1396 9846576 

  18. Topham P.S. Csizmadia V. Soler D. Hines D. Gerard C.J. Salant D.J. Hancock W.W. Lack of chemokine receptor CCR1 enhances Th1 responses and glomerular injury during nephrotoxic nephritis J. Clin. Invest. 104 1999 1549 1557 10587518 

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  20. Soto H. Wang W. Strieter R.M. Copeland N.G. Gilbert D.J. Jenkins N.A. Hedrick J. Zlotnik A. The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3 Proc. Natl. Acad. Sci. USA. 95 1998 8205 8210 9653165 

  21. Mazanet M.M. Neote K. Hughes C.C.W. Expression of IFN-inducible T cell alpha chemoattractant by human endothelial cells is cyclosporin A-resistant and promotes T cell adhesionimplications for cyclosporin A-resistant immune inflammation J. Immunol. 164 2000 5383 5388 10799902 

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