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[해외논문] Generation of Gene-Modified T Cells Reactive against the Angiogenic Kinase Insert Domain-Containing Receptor (KDR) Found on Tumor Vasculature

Human gene therapy, v.11 no.18, 2000년, pp.2445 - 2452  

Kershaw, Michael H. (Tumor Immunology Section, Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892) ,  Westwood, Jennifer A. (Tumor Immunology Section, Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892) ,  Zhu, Zhenping (Department of Molecular and Cell Biology, ImClone Systems, New York, NY 10014) ,  Witte, Larry (Department of Molecular and Cell Biology, ImClone Systems, New York, NY 10014) ,  Libutti, Steven K. (Tumor Immunology Section, Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892) ,  Hwu, Patrick (Tumor Immunology Section, Surgery Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892)

Abstract AI-Helper 아이콘AI-Helper

The destruction of newly forming tumor vasculature is a promising approach to inhibit tumor growth. The goal of the present study was to investigate whether human lymphocytes gene modified to express a chimeric receptor specific for the angiogenic endothelial cell receptor, KDR, could react against ...

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